Background and Introduction

BMIN 503

Overview

Large-scale proteomic analysis identified both diagnostic and prognostic plasma biomarkers for Parkinson’s Disease

Introduction

Background: Parkinson’s Disease (PD) is the second most common neurodegenerative disease affecting over 2 million people in the United States. Patients with Parkinson’s Disease demonstrated a series of cognitive, motor and psychotic symptoms. However, up to date, there still weren’t any cliniaclly validated blood based diagnostic test that can quickly help clinicians to confirm the diagnosis of PD. The fact that different Parkinson’s patients displayed highly heterogenous sypmtoms raised further challenges to the development of such tests. Therefore, the goal of this project is to identify any potential biomarkers associated with the diagnosis and prognosis of PD, and based on that trained a classifier that can 1) differente PD patients from non-PD patients 2) different PD patients with a faster progression rate from slowly progressing PD patients with high performance.

Goal: This project aims to conduct a large-scale proteomic analysis to screen potential plasma proteins that can A) differentiate Parkinson’s patients from normal healthy controls B) differentiate fast cognitive progressors from slow cognitive progressors based on change in MoCA (Montreal Cognitive Assessment) score change over time C) differentiate fast motor progressors from slow motor progressors based on change in UPDRS-III (Unified Parkinson’s Disease Rating Scale) score over time

Faculty and Staff Mentor:

Alice Chen-Plotkin Professor of Neurology

Marijan Posavi Senior Research Scientist

Methods

Data Source: Datasets used for this project were downloaded from NIH Parkinson’s Disease Biomarker Program database. A total of 319 PD + Normal Control Subjects were enrolled in this study through two different cohorts - University of Texas Southwestern School of Medicine and Penn State Hershey School of Medicine. A total of ~1100 plasma proteins were measured in all 319 subjects through a high through-put proteomic platform known as SomaScan. Clinical and demographic information for these patients were also collected at each cohort.

Analysis Plan:

A. Cross Section Analysis

Data Cleaning and Outlier Detection Since those samples were collected from two different cohorts, it would be helpful to start with a principle component analysis (PCA) to detect any potential batch effect. Besides, PCA analysis can help us quickly identify if there’s any significant outliers so that we can remove outliers before formal analysis

Differential Expression Analysis Compare the proteins expression level between normal control and subjects diagnosed with Parkinson’s Disease. Benjamini-Hochberg method was used to adjust for multiple comparison. Proteins that pass the adjusted p-value of 0.05 were considered as proteins that were significantly associated with the phenotype of Parkinson’s Disease. Fold change was calculated using log2(Control-PD). Vocalno plot was used to visualize the difference in protein expression between PD and control group.

3). Gene Set Enrichment Analysis (GSEA)

After identifying plasma proteins that differentiate PD from control, we created a dictionary to map protein names into their corresponding gene symbols. Using KEGG pathway files, GESA analysis was conducted to identify any potential underlying mechanisms associated with the proteins identified in the 2) and their associated genes.

4). Classifcation Analysis

Using the top 3 proteins identified through the differential expression analysis, we next trained a logistic-regression based classification model, validated with 5-fold cross validation over 50 iterations, to understand how well the top 3 proteins we identified - BSP, OMD and ApoM - together with age and sex, can help differentiate PD subjects from control subjects.

Longitudinal Analysis (Cognitive Function)

Linear-mixed effects model was used to evaluate the effect of the top protein biomarkers identified in (A) on change in MoCA score over time, after age and sex were adjusted for.

Model: MoCA ~ time x top proteins + age + sex

Longitudinal Analysis (Motor Function)

Linear-mixed efefcts model was used to evaluate the effect of the top protein biomarekrs indentified in (A) on change in UPDRS-III score over time, after age and sex were adjusted for

Model: UPDRS ~ time x top proteins + age + sex

Results

Differential Expression Analysis ended up identifying a total of 47 proteins that are differentially expressed between PD and normal. With only 8 proteins, the model already start to overfitting as you can see that the model with 8 proteins + age showed an AUC score of 0.78 on training cohort but only less than 0.6 on training cohort. However, it is also possible that there existed a significant batch effect when proteins were measured in samples in two different batches. Clustering analysis clearly showed the presence of co-linearlities between proteins, therefore it might be helpful to use some kind of feature selection algorithms to further reduce the dimensions before training the model. It is very interesting that KEGG pathway enrichment analysis showed that chemokine signaling seemed to be most significantly enriched. However, downstream manupilative experiments are needed to understand the biological meaning of that pathway. It is also very interesting that a lot of proteins showed up in the DE analysis were involved in the inflammatory reaction, like C-reactive protein. This might suggested that PD patients have a higher systemic inflammation level compared to normal control, which is consistent with the wide observation that microglia activation level in higher in the CNS of PD patients than normal control.

Furthermore, generalized linear mixed effect model with random intercept was used to study the effect of top 20 proteins on the long-term clinical outcomes (both on cognitive fucntion and on motor function). Out of the top 20 proteins, FCN1 and BSP seemed to be potential prognostic biomarkers that predict cognitve function. Patients who are in top tertile of BSP measurements developed cognitive function decline much more rapidly compared to patients in the lower two tertiles. Patients who are in the first tertile (the lowest tertile of FCN1 measuremnts) seem to have a faster cognitive function decline than those who are in the first two tertiles. Out of top 20 proteins, IFGBP.2 level seems to be correlated with the incidents of developing dementia according to the Cox Proportional Hazard model. Specifically, patients in the fourth quratile of IGFBP.2 measurements are 7 times more likely to develop dementia compared to those in the lowest quartile.

In addition, longitudinal motor function analysis suggested that NCAM.120 might be a potential biomaker for motor function over time. Patients who have lower NCAM 120 seemed to have a slower motor function progression (not very clear difference though). Also, since it looks like patients with different baseline NCAM 120 measurements have different baseline MoCA score as well, it might be useful for us to include baseline MoCA as a covariant in the LME model as well in the future.

The limit of this study is that this is an entirely analytic project, therefore, no causal relationship can be inferred. A quick screen at the top 20 proteins didn’t identify any significant pQTL effect, which made the Mendelian Randomization (MR) analysis planned in the beginning impossible to conduct. Also, since Somalogic is a new proteomic platform, it remains unknown how reliable the protein measurements are. Therefore, it might be interesting to use ELISA essay to validate some of the proteomic measurements to see how valid they are.

Quick Summary of Replication Cohort

# Read the proteomic dataset
setwd('/Users/junchaoshen/UPenn BMI')
df = read.csv('Protein Demographic.csv',skip = 6)
kable(df[1:5,], "html") %>% kable_styling("striped") %>% scroll_box(width = "100%")

GUID	Group	Site	Age	LDOPADoseTm	MDS_UPDRS.Total.Score	Gender	PlateId	CHIP	CEBPB	NSE	PIAS4	IL.10.Ra	STAT3	IRF1	c.Jun	Mcl.1	OAS1	c.Myc	SMAD3	SMAD2	IL.23	PDGFRA	IL.12	STAT1	STAT6	LRRK2	Osteocalcin	IL.5	GPDA	IgA	LPPL	HEMK2	PDXK	TLR4	REG4	HSP.27	YKL.40	Alpha.enolase	Apo.L1	CD38	CD59	FABPL	GDF.11	BTC	HIF.1a	S100A6	SECTM1	RSPO3	PSP	Apoptosis.regulator.Bcl.W	VEGF.D	SOST	FAM3D	CSH	EFNB1	SNP25	LYPD3	NEGR1	BCL6	FSTL1	Osteopontin	Lumican	CD177	CHKB	SMOC1	protein.Z.inhibitor	FLRT2	FLRT3	ISLR2	Vitronectin	DSC2	LDLR	HXK2	HXK1	SEM5A	LTBP4	PIANP	Adrenomedullin	S100A4	RNF43	TRAIL.R4	ZNRF3	GI24	Ephrin.A2	ApoM	IFN.b	IFN10	IFNA7	EFNB2	HHLA2	IL.1.sRII	AMGO2	RXFP1	C1QR1	NRG4	H2B2E	H2A3	H31	IFN.g	IL.1F8	IL.1F6	UCRP	Ephrin.A3	X14.3.3.protein.beta.alpha	X14.3.3E	Annexin.V	Myostatin	C4b	Coagulation.Factor.XI	CTACK	Endostatin	TIMP.1	tPA	EG.VEGF	TIMP.2	TGF.b1	VEGF.sR3	C5	Apo.E	BDNF	C8	Cathepsin.G	CXCL16..soluble	FGF.10	FGF.8B	GIIE	GV	MIP.3a	SAP	SCF.sR	TIMP.3	Angiopoietin.4	Cadherin.E	GFRa.3	Ephrin.B3	GFRa.2	X6Ckine	HMG.1	OPG	b.Endorphin	Factor.I	IGFBP.3	MCP.1	MMP.9	Myeloperoxidase	PRL	VEGF	X4.1BB	X4.1BB.ligand	Angiopoietin.2	B7	CD30	CLF.1.CLC.Complex	Cystatin.C	Dtk	eIF.5	Ephrin.A4	Ephrin.A5	ERBB2	ERBB3	ERBB4	GA733.1.protein	gp130..soluble	HO.2	HPV.E7.Type.16	HPV.E7.Type18	HSP.90a.b	IL.1.R.AcP	IL.10.Rb	IL.12.Rb1	IL.13.Ra1	IL.2.sRg	Layilin	Lymphotoxin.b.R	Macrophage.mannose.receptor	M.CSF.R	MSP.R	PAFAH.beta.subunit	P.Cadherin	PKC.A	PKC.Z	Rab.GDP.dissociation.inhibitor.beta	sICAM.3	suPAR	TNF.sR.I	TrkC	BCMA	Bone.proteoglycan.II	Calpain.I	CK.MM	ERBB1	HGF	HSP.60	iC3b	IGFBP.5	IGFBP.6	MIA	NPS.PLA2	OSM	PECAM.1	Persephin	PF.4	Protein.S	TACI	TECK	Thyroxine.Binding.Globulin	TNFSF18	CNTFR.alpha	EMAP.2	EPO.R	G.CSF.R	IL.1F7	Laminin	MICA	NADPH.P450.Oxidoreductase	NANOG	NKp44	NovH	Siglec.6	Siglec.7	Sonic.Hedgehog	IgG	TSLP.R	ULBP.3	Activin.A	Apo.A.I	Azurocidin	BMP.14	C1q	C3	C3adesArg	DRR1	FGF.18	FGF.19	FGF.20	FGF9	GDF.11.8	Hemopexin	HIV.2.Rev	I.309	IGFBP.1	IL.10	IL.16	IL.17F	IL.22	Lactoferrin	LAG.1	LD78.beta	MCP.2	MMP.3	MMP.7	NAP.2	SOD	Fibrinogen	Apo.B	ACE2	Activin.RIB	ADAMTS.4	Angiopoietin.1	ART	BCAM	Cadherin.5	CD97	COMMD7	EDA	Fractalkine.CX3CL.1	HAI.1	IL.27	Kallikrein.11	Kallikrein.4	kallikrein.8	Ku70	Lipocalin.2	Met	MMP.17	OX40.Ligand	sFRP.3	SPINT2	sTie.1	Ubiquitin.1	WIF.1	AIF1	C5a	CHK1	ERK.1	Glucocorticoid.receptor	Hat1	HDAC8	Karyopherin.a2	MEK1	MOZ	PKC.D	RAC1	RAD51	TBP	Topoisomerase.I	UBC9	YES	a1.Antichymotrypsin	C7	Cardiotrophin.1	CCL28	CD22	HCC.1	IL.4	Midkine	MPIF.1	PCNA	sRANKL	PAI.1	Apo.E3	Apo.E4	Artemin	Cytochrome.c	Cytochrome.P450.3A4	DAN	ER	Factor.D	Growth.hormone.receptor	GX	IGFBP.4	IGF.I	Luteinizing.hormone	Properdin	Protein.C	PTHrP	SCGF.beta	VCAM.1	TNFSF15	ALK.1	AREG	BMP.7	CD36.ANTIGEN	contactin.1	CTGF	Desmoglein.1	EDAR	ENA.78	ESAM	Galectin.4	Gro.a	Gro.b.g	Histone.H1.2	ICOS	IL.1.sRI	IL.17.sR	IL.18.Rb	IL.1Rrp2	JAM.B	JAM.C	LSAMP	MBL	NKp30	PD.L2	PTP.1B	Siglec.9	TGF.b.R.III	TSLP	CTLA.4	a2.Antiplasmin	bFGF	Calpastatin	Ck.b.8.1	DC.SIGN	DC.SIGNR	FSH	Galectin.2	GFAP	IL.19	IL.1b	I.TAC	MIP.1a	MRC2	Myoglobin	ON	PARC	PTN	resistin	Trypsin	vWF	Fas.ligand..soluble	Flt3.ligand	Haptoglobin..Mixed.Type	IL.4.sR	NKG2D	WISP.1	BAFF	C9	Cathepsin.B	FGF.5	Galectin.3	GDF.9	IgM	IL.2	IL.13	IL.18.BPa	LBP	Coagulation.Factor.Xa	PlGF	TIG2	ULBP.1	ULBP.2	XEDAR	Aurora.kinase.A	MK01	SMAC	VEGF.C	sCD4	IL.2.sRa	TNF.sR.II	Siglec.3	ADAMTS.5	IDUA	AMPM2	amyloid.precursor.protein	ARSB	ASAHL	ATS1	ATS13	Carbonic.Anhydrase.IV	CATC	Cathepsin.A	Cathepsin.S	CD39	Coagulation.Factor.VII	C2	CRIS3	Enterokinase	WFKN1	Glutamate.carboxypeptidase	GPVI	Granulysin	HPLN1	IDE	IDS	kallikrein.12	kallikrein.13	kallikrein.5	KREM2	LKHA4	LYVE1	MATN3	MEPE	METAP1	ASAH2	Nidogen	PIGR	Protease.nexin.I	RET	SARP.2	Semaphorin.3A	TrATPase	URB	WFKN2	Aggrecan	ANGL3	BGH3	BGN	C1r	Carbonic.Anhydrase.X	CD109	CD23	CD48	CD5L	CFC1	CNTN2	Contactin.4	Contactin.5	CYTF	Cystatin.M	DLL4	FCG2A	FCG2B	FCG3B	FCGR1	FCN2	GFRa.1	GPC2	Heparin.cofactor.II	HTRA2	IGFBP.7	IL24	LRIG3	LRP8	LY9	MATN2	Nectin.like.protein.2	NET4	PGRP.S	RGMB	RGM.C	TFPI	TSP2	TSP4	ABL1	Aminoacylase.1	Antithrombin.III	AURKB	BARK1	BMP.1	CAMK2A	CAMK2B	Carbonic.anhydrase.6	Carbonic.anhydrase.VII	CDK2.cyclin.A	CDK5.p35	CDK8.cyclin.C	Chk2	CLC4K	CRDL1	CSK	Cathepsin.V	Dkk.4	ECM1	FETUB	Granzyme.H	HCK	IL.17.RD	Kallikrein.7	KPCI	LYNB	PAK3	PAK7	PCI	PIK3CA.PIK3R1	PK3CG	PKB.a.b.g	PLK.1	Renin	SHP.2	STAB2	TBK1	TCPTP	TPSB2	TPSG1	UFC1	Bcl.2	BFL1	BMX	BSP	BTK	CAMK1D	CAMK2D	Carbonic.anhydrase.XIII	CD30.Ligand	CDK1.cyclin.B	Chymase	CSK21	EphA1	EPHA3	FN1.3	FN1.4	Flt.3	FSTL3	granzyme.A	GSK.3.alpha.beta	HIPK3	IL.15.Ra	IL.18.Ra	IL.8	IR	Kallistatin	Kallikrein.6	LCK	LYN	Periostin	PDGF.Rb	PGCB	PRKACA	RPS6KA3	sE.Selectin	STK16	Survivin	Thrombopoietin.Receptor	Thrombospondin.1	TrkA	TRY3	DUS3	XPNPEP1	Angiotensinogen	b2.Microglobulin	b.ECGF	BLC	Catalase	CNTF	FGF.17	GCP.2	IFN.aA	IL.17B	Integrin.a1b1	LEAP.1	Lymphotoxin.a1.b2	Lymphotoxin.a2.b1	MDC	MIP.5	Proteinase.3	SDF.1	TAFI	TARC	TGF.b3	TSH	Vasoactive.Intestinal.Peptide	CD40.ligand..soluble	DKK1	dopa.decarboxylase	Adiponectin	a1.Antitrypsin	a2.HS.Glycoprotein	Arylsulfatase.A	BASI	BMP10	Cadherin.6	CAMK1	Caspase.3	CATE	Chitotriosidase.1	CHL1	CLC7A	MASP3	Discoidin.domain.receptor.2	DKK3	DPP2	Endothelin.converting.enzyme.1	EphB4	FCN1	GNS	HGFA	IL22RA1	LGMN	LY86	Marapsin	MMEL2	MP2K2	MRCKB	Nectin.like.protein.1	NID2	OBCAM	OCAD1	OLR1	RAP	SLAF5	SLIK1	Soggy.1	TEC	TLR4.MD.2.complex	VEGF.sR2	BMPER	Cadherin.12	Calcineurin.B.a	complement.factor.H.related.5	IGF.II.receptor	kallikrein.14	Macrophage.scavenger.receptor	MFRP	Albumin	a2.Macroglobulin	ALT	Angiostatin	CK.MB	p27Kip1	BNP.32	PYY	Secretin	TNR4	CSF.1	Activated.Protein.C	COX.2	STX1a	sTie.2	ADAM.9	ANGL4	Cadherin.2	Carbonic.anhydrase.9	Carbonic.anhydrase.III	CK.BB	Cystatin.S	CYTD	Endocan	EphA5	FGF23	FGFR.2	FGFR.3	FGR	FYN	IL.12.RB2	KPCT	MAPK2	MAPK5	MAPKAPK3	MATK	MK08	PAK6	PDGF.CC	pTEN	PTK6	TLR2	UFM1	AIP	Cyclophilin.A	DLRB1	ETHE1	GAPDH..liver	HSP.40	MDHC	NACA	Peroxiredoxin.1	PPAC	PSA1	PSA6	RS7	RSK.like.protein.kinase	SBDS	SE6L2	SGTA	TCTP	TMA	UB2L3	ARI3A	CaMKK.alpha	CDC37	DLC8	IMB1	ING1	Lamin.B1	LDH.H.1	MBD4	Mesothelin	NAGK	Phosphoglycerate.mutase.1	PLPP	PSD7	SKP1	Sorting.nexin.4	UBE2N	discoidin.domain.receptor.1	FGF.4	HSP.70	sRAGE	BPI	C6	Eotaxin.2	Factor.B	FGF.6	Fibronectin	FST	Granzyme.B	HB.EGF	IgE	IL.17D	IL.17E	IL.20	IL.6.sRa	IL.7	IP.10	Lymphotactin	MCP.4	Neurotrophin.3	Neurotrophin.5	PAPP.A	PDGF.BB	Plasmin	Plasminogen	Prekallikrein	alpha.1.antichymotrypsin.complex	P.Selectin	Tenascin	TGF.b2	Thrombin	uPA	Factor.H	MMP.2	Transferrin	Histone.H2A.z	Thyroglobulin	X14.3.3	X4EBP2	X6.Phosphogluconate.dehydrogenase	Aflatoxin.B1.aldehyde.reductase	AK1A1	AN32B	Cofilin.1	DRG.1	EP15R	ERAB	FER	HNRPQ	IF4G2	IGF.I.sR	IL.1.R4	LCMT1	LIN7B	M2.PK	MDM2	NCAM.L1	NDP.kinase.B	NSF1C	NUDC3	PA2G4	paraoxonase.1	PESC	PFD5	PHI	prostatic.binding.protein	Protein.disulfide.isomerase	PSA2	RAN	RBM39	SNAA	Sphingosine.kinase.1	Spondin.1	Thymidine.kinase	transcription.factor.MLR1..isoform.CRA_b	Transketolase	Triosephosphate.isomerase	XTP3A	PTP.1C	AMNLS	CYTT	BOC	CLC1B	SAA	CRP	sICAM.1	DAPK2	DYRK3	MIC.1	DHH	FGF.12	FGF.16	FGF.8A	IFN.lambda.1	IFN.lambda.2	MSP	SLPI	SP.D	ADAM12	BCL2.like.1.protein	CHST2	CHST6	Collectin.Kidney.1	ENPP7	ENTP3	ENTP5	FCRL3	GREM1	hnRNP.A.B	LRRT1	LRRT3	MFGM	PCSK7	PDPK1	Sialoadhesin	SPARCL1	SPHK2	ST4S6	TGM3	Tropomyosin.2	Ubiquitin	ZAP70	C1.Esterase.Inhibitor	C3b	C4	C5b..6.Complex	FGF7	IL.3.Ra	IL.5.Ra	IL.11	Kininogen..HMW	MMP.12	NCAM.120	PDGF.AA	SCGF.alpha	ATS15	BSSP4	BST1	CBX5	CDON	Clusterin	CONA1	CTAP.III	DnaJ.homolog	EMR2	FLRT1	Fucosyltransferase.3	FUT5	GP114	HDGR2	IL.34	KIRR3	KYNU	Livin.B	NXPH1	PLCG1	PLXC1	RSPO2	SH21A	SLIK5	SORC2	PH	IL.6	X3HIDH	GM.CSF	TNF.b	X41	X17.beta.HSD.1	Apo.D	IL.3	PPIB	Protein.disulfide.isomerase.A3	TFF3	Afamin	Olfactomedin.4	ASM3A	FAM107B	Gelsolin	CBG	Cytidylate.kinase	C34.gp41.HIV.Fragment	PERL	CO8A1	ITI.heavy.chain.H4	TXD12	STRATIFIN	sL.Selectin	TRAIL.R1	Epithelial.cell.kinase	G.CSF	Glypican.3	IL.1a	BMPR1A	BMP.RII	TrkB	VEGF121	Angiogenin	Coagulation.Factor.IX	Coagulation.Factor.X	GDF2	Insulin	MCP.3	WNT7A	ACTH	Glucagon	C3a	Calcineurin	Caspase.2	Coactosin.like.protein	Coagulation.Factor.V	D.dimer	Endoglin	Galectin.8	GIB	Glutathione.S.transferase.Pi	GOT1	HCC.4	HCG	Hemoglobin	IgD	Integrin.aVb5	Lysozyme	MIP.3b	MIS	MMP.1	MMP.13	SHBG	Stanniocalcin.1	TF	EPI	X40S.ribosomal.protein.SA	AGR2	annexin.I	annexin.II	ARMEL	ARP19	ARTS1	ATP.synthase.beta.chain	C1QBP	CAPG	Carbonic.anhydrase.I	carbonic.anhydrase.II	CATZ	cIAP.2	CRK	DBNL	DERM	DSC3	Elafin	ERP29	Esterase.D	FABPE	FAK1	FCAR	FGFR4	Fibrinogen.g.chain.dimer	GP1BA	GPC5	GRN	GSTA3	hnRNP.K	HPG.	HRG	IF4A3	JAK2	LG3BP	Mammaglobin.2	MMP.14	MK11	MK12	MK13	MAPK14	Mn.SOD	Moesin	PBEF	Myokinase..human	NCC27	NCK1	PAFAH	PARK7	Peroxiredoxin.5	Peroxiredoxin.6	PGP9.5	phosphoglycerate.kinase.1	PPase	PUR8	Rb	RS3	sCD163	SEPR	SIRT2	SPTA2	SSRP1	Tropomyosin.1.alpha.chain	Trypsin.2	TS	TSG.6	B7.H1	B7.H2	CD226	CD244	CD83	CLM6	CRTAM	DAF	DcR3	EPHAA	EPHB2	EphB6	GPNMB	IL.1.sR9	IL.17B.R	IL.20.Ra	IL.22BP	IL.23.R	IL.7.Ra	ILT.2	ILT.4	JAG1	JAG2	JAML1	KI2L4	KI3L2	KI3S1	KLRF1	LAG.3	LIMP.II	MICB	MO2R1	NKp46	Nogo.Receptor	NOTC2	Notch.1	Notch.3	Nr.CAM	NRX1B	NRX3B	OX2G	Prolactin.Receptor	RELT	ROBO2	ROBO3	SEM6B	Semaphorin.6A	sICAM.5	SIG14	SLAF6	SREC.I	SREC.II	TAJ	TCCR	TGF.b.R.II	TIMD3	TWEAKR	UNC5H3	UNC5H4	PDE7A	AMPK.a1b1g1	K.ras	NMT1	PDE9A	PPID	PSME3	GCKR	CK2.A1.B	CK2.A2.B	PDK1	KIF23	IMDH1	HMGR	PCSK9	NR1D1	PPIE	MP2K4	JNK2	AMPK.a2b2g1	cGMP.stimulated.PDE	Cyclophilin.F	DRAK2	IMDH2	PDE11	PDE1A	PDE3A	PDE4D	PDE5A	TAK1.TAB1	TYK2	ABL2	BCAR3	calreticulin	GRB2.related.adapter.protein.2	MMP.16	RAC3	SHC1	VAV	GHC2	Eotaxin	Coagulation.Factor.IXab	Elastase	Apo.E2	Troponin.T	Prothrombin	EGFRvIII	annexin.VI	B7.2	calgranulin.B	Caspase.10	CBPE	CKAP2	CPNE1	Cyclin.B1	DLL1	GPC6	hnRNP.A2.B1	HVEM	IL.1Ra	Keratin.18	LIGHT	MIF	NLGNX	OMD	PIM1	PKB.beta	Semaphorin.3E	SET	BAFF.Receptor	BRF.1	Fas..soluble	sLeptin.R	DR6	CAD15	CD27	RANK	SHPS1	FABP	Troponin.I..skeletal..fast.twitch	Troponin.I	ANP	ALCAM	ASGR1	CNDP1	COLEC12	CYTN	DEAD.box.protein.19B	Ficolin.3	GAS1	GRB2.adapter.protein	H6ST1	HSP.90b	IL.17.RC	MED.1	PKC.B.II	PKC.G	PSMA	RANTES	RASA1	RBP	RGMA	RS3A	sICAM.2	SLAF7	SRCN1	Stress.induced.phosphoprotein.1	Testican.1	Testican.2	WNK3	RUXF	Cathepsin.D	EGF	GITR	bFGF.R	TRAIL.R2	NRP1	AFP	BID	b.NGF	C3d	CD70	Cripto	Epo	GDNF	IFN.g.R1	IL.9	LIF.sR	NG36	Noggin	S100A12	tau	X14.3.3.protein.zeta.delta	X3HAO	aldolase.A	ARGI1	BAD	Dynactin.subunit.2	EF.1.beta	eIF.4H	eIF.5A.1	Gastrin.releasing.peptide	HINT1	HSP70.protein.8	Nucleoside.diphosphate.kinase.A	PEX5	PSME1	S100A7	WISP.3	Ferritin	TNF.a	TWEAK	Tpo	PTH	Somatostatin.28	MP2K3	p53	PolyUbiquitin.K48	PolyUbiquitin.K63	NET1	CD47	ANK2	X14.3.3.protein.theta	CREL1	Lectin..mannose.binding.2	LRP1B	MYPC1	N.terminal.pro.BNP	Tropomyosin.4	PACAP.27	ghrelin	PACAP.38	a.Synuclein	BMP.6	HGH	SOD3	RSPO4	Cathepsin.H	Activin.AB	PSA	IGFBP.2	RNase.H1	ROR1	CgA	MMP.10	FBLN3	Leptin	KEAP1	gpIIbIIIa	Eotaxin.3	SUMO3	IL.17	CSRP3	MMP.8	PGM1	DSCAM	MUC1	FAM3B	NEUREGULIN.1	INGR2	sLRP1	IFN.a.b.R1	TFF1	HMGN1	MIG	CD63	Trefoil.factor.2	Galectin.7	LEG9	UB2G2	Transgelin.2	ATPO	Corticotropin.lipotropin	QORL1	PEDF	CATF	FTCD	UBP25	PLXB2
PDJA900DTV	PD	UTSW	75.4	900	59	Male	Set.2	622.8	777.0	13270.8	758.2	1566.3	535.7	1099.4	3278.6	1213.1	444.0	396.5	5958.3	4141.0	1975.0	1374.4	270.4	3393.6	262.7	1799.5	13617.1	441.9	1928.4	3838.0	674.2	1335.4	263.5	358.8	2881.7	2385.7	9108.6	12010.7	34379.0	720.8	3455.3	9422.4	968.5	854.9	495.3	1049.5	1857.9	1859.7	789.6	530.0	801.4	61475.6	44835.6	1962.8	2262.4	1672.6	996.2	6736.5	1626.5	44037.0	4983.9	1556.7	1158.0	1987.6	5300.6	5374.3	30057.5	3873.9	7025.3	81392.8	5210.4	175.9	463.5	1138.8	6108.5	2070.5	7668.0	1766.8	1866.3	1067.0	1170.6	652.4	507.3	2121.9	17702.8	600.5	351.4	321.4	19299.7	886.9	14621.2	2314.6	435.8	15967.2	1034.0	11992.3	599.2	1559.2	1368.6	482.6	639.1	2733.4	2465.7	6046.2	752.2	812.5	7784.8	517.1	1404.8	3156.4	106204.8	99.4	679.5	541.9	438.4	1366.0	9119.1	7429.0	53512.9	833.9	3623.3	896.0	15844.8	729.2	712.7	302.7	407.7	167.6	43679.1	21319.3	987.2	1287.8	74597.2	956.2	1354.4	6978.2	26884.9	3535.9	14268.0	827.4	40698.9	1807.7	1105.2	6138.8	18582.5	2323.7	19097.5	454.5	884.1	178.9	840.5	1124.7	519.8	4837.1	588.4	908.0	3398.8	5800.2	455.0	341.7	203.2	564.9	7718.2	1030.7	488.5	1992.5	2888.1	22621.2	1263.4	546.0	3640.7	1769.9	2175.9	6109.2	10453.8	198.9	521.9	3298.7	31645.8	10387.3	668.4	7144.0	782.3	12260.0	2646.9	5915.3	11910.0	3367.0	18937.7	1103.4	26720.0	1435.9	3224.9	8723.2	2636.4	1337.2	4698.1	4239.2	1921.5	1004.0	551.6	27153.0	5597.1	1030.3	1526.9	41172.1	600.7	14404.9	3171.4	319.5	913.7	2041.3	2268.9	721.8	2530.0	230.5	356.8	590.3	5072.0	1700.9	762.4	199622.0	1014.0	494.2	4331.5	18790.8	258.1	2493.0	47113.7	60507.9	169741.8	471.6	351.0	29909.2	357.0	614.6	1215.3	1170.8	236.4	3234.0	1282.3	233.9	312.4	1109.0	1094.9	39463.4	414.8	1849.1	265.5	661.7	2196.9	6797.1	701.9	154812.8	13147.8	507.9	285.5	218.9	661.6	3649.0	2107.4	15123.2	1697.2	2934.3	1648.5	5296.0	7533.9	939.4	1114.5	421.3	3544.0	241.3	31238.4	9418.3	1244.3	326.0	4592.5	1310.7	11528.8	1292.8	3959.6	2074.4	13162.7	1709.1	9941.4	88.9	365.6	1600.5	296.3	389.3	2240.9	3241.1	6666.9	2374.5	555.5	517.0	695.6	796.2	295374.4	1719.0	692.3	4530.6	780.1	14135.4	478.2	23670.7	4990.2	193.2	523.4	935.6	284209.3	277764.1	569.1	1822.7	7991.9	2107.2	774.8	1651.0	1549.3	593.3	9317.1	1005.3	1260.7	152005.8	1212.5	1088.0	963.6	24066.5	1138.8	1395.0	881.3	751.1	8354.6	247.2	1032.7	2261.7	829.4	487.2	6345.6	615.9	48551.4	655.4	1044.3	587.6	13999.1	596.5	287.6	754.3	13076.9	3494.2	1973.4	11596.3	1492.0	6089.3	1644.9	19919.6	42259.3	311.8	173.0	1806.5	1470.3	6515.4	110702.1	3007.8	39277.7	1685.0	464.9	545.8	6584.3	2429.0	2065.1	836.6	4510.8	3926.3	19742.7	7333.8	2142.9	1785.6	8072.7	13378.5	423.2	463.2	37044.5	248.4	614.8	3797.0	1326.7	68333.0	2136.3	651.7	25748.7	639.8	3855.1	1529.5	635.2	19239.3	119542.6	4788.4	302.6	3283.6	360.4	297.9	1086.6	981.3	2416.9	5842.5	1041.2	410.2	816.8	21778.4	7536.1	280.9	1559.3	11643.4	20397.0	982.1	6177.7	339.6	3592.2	2108.3	710.4	7568.5	876.9	1440.0	614.7	2558.3	247.8	395.9	1749.9	6093.6	7412.4	1820.8	1024.6	1178.8	3170.3	4488.2	1180.9	262.1	1474.0	1147.4	345.5	578.0	277.4	1000.5	3380.3	5454.0	2674.6	8687.9	1400.0	4334.2	1623.3	8687.5	2790.4	6912.4	563.2	393.5	49283.7	1318.7	2680.8	702.4	3098.8	7734.3	893.6	2721.0	1657.7	1012.8	4173.7	611.5	453.9	21971.9	416.2	3094.9	6276.5	1808.7	297.8	1871.3	1668.1	164.1	3583.3	4639.0	77624.2	223.0	7131.1	2562.3	1789.3	14551.2	2833.9	945.9	525.8	3391.3	1420.1	82138.9	20533.3	647.1	370.0	3313.5	128498.5	1028.4	1859.2	2643.9	507.9	912.4	2460.9	439.8	452.2	1358.6	1529.5	197.8	216.3	3535.2	1531.9	3010.9	7114.4	21635.6	5132.5	601.1	326.2	583.9	1489.3	1165.9	8359.6	1259.3	2336.3	120041.1	5555.5	3495.9	1722.3	277.0	1738.5	2364.0	1440.9	618.2	1175.7	1775.8	382.3	8438.2	968.6	850.1	334.8	5341.0	1965.3	2770.5	2523.5	496.0	1827.6	618.1	490.5	378.8	13654.5	170.7	2260.8	66654.5	1778.2	13251.6	3195.8	3995.9	853.8	937.5	13703.8	934.9	8634.6	47638.0	2496.9	316.4	1453.7	5971.2	3447.3	1344.5	391.0	312.9	19612.2	2080.7	760.7	212.1	2824.0	3070.5	508.1	631.0	1809.4	7096.2	3472.5	222.2	6354.5	8560.4	427.6	216.9	2569.6	170.5	171.3	650.6	19438.0	115.5	2434.7	1152.5	6711.6	5256.3	5958.9	13944.4	1315.6	554.5	783.4	244.6	215.7	29464.8	249.1	4147.5	932.4	2019.2	1379.2	416.1	1505.2	538.1	6240.9	2374.4	575.2	2792.3	12638.3	713.2	5960.1	1607.6	8409.9	1488.1	21027.1	2619.2	1619.7	9999.1	4103.8	957.2	2314.2	4388.1	5902.9	967.4	3474.4	1166.5	1593.1	2533.7	2630.1	827.0	1288.0	593.0	7006.9	1222.7	2298.6	1253.2	5232.9	7464.5	444.4	556.7	6138.3	996.9	45455.5	7191.4	784.3	1508.0	12059.3	15792.1	2570.7	18922.6	630.0	670.9	797.2	2235.8	195.0	830.4	1227.8	717.2	606.0	490.8	2354.7	1222.7	6604.9	2013.7	1771.3	6719.2	824.3	157.9	8780.1	1280.8	975.7	535.6	325.4	867.5	260.3	2054.0	803.8	1608.0	3156.8	528.9	604.2	476.4	474.2	3225.9	390.0	489.9	270.6	569.6	1330.1	3493.0	53315.7	901.7	3717.4	25547.8	222.4	10843.1	3654.7	1547.5	2857.5	564.4	471.0	719.6	158.2	3416.6	750.7	744.3	3850.8	1585.9	830.5	347.2	224.2	533.8	537.5	2128.9	5597.4	750.3	818.2	452.2	322.7	736.5	8193.1	1282.2	303.5	3258.7	3423.2	1491.7	313.9	696.1	9259.0	1280.5	576.7	81719.2	776.4	24883.0	325.6	10087.0	648.8	537.7	290.7	2632.4	219.6	322.2	822.1	13611.0	168.7	2030.9	511.6	432.0	287.1	349.8	23621.7	20782.4	820.1	3879.1	21329.6	7105.7	18729.1	28325.2	344.9	823.9	1953.5	63840.3	8518.8	247609.2	1586.4	472.7	1366.5	370.0	2497.0	881.4	2826.2	214.7	3146.0	6729.7	4044.2	1074.1	641.2	1977.7	835.2	8546.0	4405.2	1782.7	635.4	9146.1	218.1	505.5	3583.4	229.3	279.1	412.0	181.3	233.6	380.5	8002.5	3605.6	271.5	574.1	1056.5	374.5	1578.9	2388.3	2844.8	508.1	269.5	12537.6	2025.5	8646.1	1222.3	238.7	24206.9	1154.2	10311.9	548.1	20745.4	1861.2	1885.9	2061.4	2277.1	305.2	250.3	658.7	213.5	245.4	355.4	3495.1	48707.5	2347.1	585.5	1024.3	2421.3	416.4	14004.7	10941.4	1024.8	3604.6	392.8	445.9	819.0	150.4	255.4	1735.7	1297.6	442.3	131.6	15808.9	734.4	6456.8	164.1	2066.8	818.7	11606.6	11749.5	16721.9	128761.8	428.0	1114.4	785.5	1498.1	293.9	35677.1	1807.5	13878.7	11636.3	2199.7	733.6	2795.1	8168.7	432.8	5398.6	1112.7	1446.1	18210.9	602.5	1038.5	663.6	508.4	7997.0	573.7	742.9	781.2	460.7	557.2	133.0	6762.0	554.1	684.3	499.1	16077.4	2713.8	3420.6	2312.9	356.5	676.4	341.7	604.0	1771.2	1824.0	4501.2	1656.3	3293.9	2293.4	22771.6	26428.8	263.6	3112.5	2030.2	1135.9	569.5	4346.6	1738.6	1132.1	548.7	41991.2	1790.8	726.6	3706.5	1379.9	5514.3	1423.3	723.5	668.4	790.2	496.8	1308.7	535.0	5428.1	13411.0	6099.6	2407.8	170.9	737.0	247.6	543.3	3477.0	292.0	666.8	781.0	2043.6	68383.3	12753.6	1511.7	557.6	720.0	4575.6	3090.2	44970.3	1443.3	507.5	4859.4	1164.8	126467.1	1050.0	11225.5	446.2	663.5	2931.9	2829.3	2586.8	605.7	1705.6	796.4	3646.9	5318.6	6369.1	832.3	74767.0	1654.1	4642.7	2033.0	7801.6	197.0	6785.4	220.9	3814.4	1947.7	8720.1	1192.2	25041.6	9438.2	974.6	782.9	327.7	210.9	1310.5	56929.1	1776.1	510.2	25385.8	199.8	300.9	1053.5	3647.9	360.3	119253.8	1438.3	8089.5	1172.7	709.8	797.4	603.9	776.4	44522.9	732.4	588.6	7007.0	1140.6	819.3	876.4	394.7	507.2	103.7	1321.9	1711.3	12620.8	3817.8	1336.4	335.5	3635.1	882.0	4251.2	239.0	446.9	997.2	5826.3	576.0	1663.2	882.9	949.1	747.9	182.2	294.5	5792.0	678.6	25169.6	701.3	396.7	24960.8	2853.7	6269.8	1892.0	1315.8	293.1	1429.4	3355.1	207.1	4700.6	11795.4	719.2	332.1	752.0	1726.3	265.8	367.0	344.4	8623.5	441.3	1085.6	1128.9	3644.7	3532.2	961.1	25269.2	609.3	18101.6	1180.7	1623.5	3046.8	1307.0	4657.9	3843.1	376.7	3647.1	11373.3	1102.5	33680.5	438.2	12099.7	257.8	1703.6	1590.2	975.0	14707.8	133.9	6050.5	7780.3	350.9	423.3	1834.1	1192.1	701.3	3023.9	274.5	521.5	1887.0	386.9	3067.6	502.0	798.7	370.7	621.2	536.3	500.6	43603.0	1357.5	1446.7	4339.0	2112.0	3211.4	1777.2	1456.5	547.4	741.5	1288.9	5705.9	1355.6	1672.1	1568.0	1335.8	3124.2	484.8	669.8	3455.4	5591.0	3343.5	965.9	15375.2	9634.6	411.3	328646.4	6104.2	166369.1	206.4	8073.7	846.3	3350.8	4753.7	2378.5	11857.0	609.2	582.6	3292.3	1792.1	2061.7	795.3	3413.8	825.5	485.5	886.6	878.9	6979.1	856.6	4390.1	2657.9	615.7	1615.0	1535.6	2845.3	2315.5	11419.9	3578.8	7057.7	1437.7	7087.0	24170.9	12539.5	772.6	1104.5	18960.5	1547.2	5048.2	2377.1	1538.2	1513.1	1133.6	1188.3	9390.3	3208.0	19252.8	1291.2	93487.1	1840.7	686.2	448.2	43596.3	878.5	359.7	28560.8	592.0	1341.8	40380.1	12575.8	2543.5	1859.2	760.3	407.7	2646.6	761.3	997.4	1337.9	925.4	453.6	2891.5	635.4	1074.6	571.6	11424.5	309.7	734.1	1843.6	414.5	519.9	218.1	5192.1	732.0	2897.8	649.0	191.5	49879.3	5384.6	40994.0	823.3	2801.7	2015.2	282.5	1194.8	9969.8	350.8	916.7	1151.9	482.8	247.5	688.7	420.2	1452.2	7773.9	672.1	737.6	207.3	5062.1	1473.9	1361.6	866.6	1310.2	5646.9	810.5	489.0	496.6	878.3	6268.7	13169.0	41426.6	2976.1	28686.6	23680.6	332.8	1090.7	230.0	3019.4	27463.1	253.7	564.3	605.2	608.8	888.7	14912.7	934.7	162.5	1187.7	59237.8	843.0	2080.2	4661.9	469.1	1176.2	769.2	1333.9	345.8	3786.6	1039.3	608.2	1231.1	1426.6	1912.5	232.3	434.3	1679.7	1536.4	2848.7	517.5	650.0	320.0	21729.3	546.6	2076.4	5486.4	2933.7	1567.9	2782.2	2847.7	77433.7	2874.4	9335.7	942.1	5295.8
PDBC103ZEP	PD	UTSW	63.0	150	63	Male	Set.2	527.1	833.0	10728.8	672.8	1672.1	865.8	1376.2	8185.3	1913.8	349.6	674.9	8455.8	5591.5	1583.3	1154.0	254.3	7736.1	333.8	1825.5	975.5	498.8	1313.2	3274.6	666.1	1678.7	285.7	315.8	2354.9	9446.0	34610.7	20595.7	33277.5	817.4	2643.9	3157.1	905.3	550.2	553.5	1418.8	1772.0	1726.9	788.4	754.5	668.5	79532.5	11463.7	2622.9	2005.9	1883.8	1023.5	6231.7	1407.3	41527.4	3397.7	1616.4	997.0	2647.1	4526.0	6561.1	27730.2	3401.0	8906.5	37689.4	3901.9	178.2	1212.8	1315.6	6456.5	1708.1	6338.7	1716.2	1735.7	1088.5	915.7	425.6	514.4	1514.7	13227.4	772.1	345.3	335.5	15878.9	834.1	11139.8	2169.6	454.3	17150.8	998.9	13200.8	520.9	1013.3	719.7	519.5	683.1	1058.5	2391.1	8044.5	620.8	895.3	7401.5	321.1	1557.9	1298.0	100917.5	95.2	800.4	190.0	362.6	1422.9	9362.1	6863.1	72833.1	888.5	3851.7	974.5	14337.2	240.3	746.6	310.7	287.4	165.3	50953.1	20173.5	1782.1	565.8	77925.0	1243.9	1009.3	6446.3	27692.7	4989.4	15809.2	931.3	50498.6	1376.4	1662.4	9559.6	13774.0	2901.6	14137.7	410.9	859.3	157.6	675.0	1133.0	569.5	3434.3	544.2	901.8	2967.7	4287.6	431.2	290.4	214.8	350.6	8464.4	408.5	546.2	2334.8	3921.9	24888.5	1280.3	639.8	3998.9	1297.9	1783.4	7105.5	13571.8	182.3	590.3	3316.9	28046.8	14096.8	798.1	8940.8	705.2	11765.9	2199.0	5395.6	9191.8	3551.3	18064.8	1057.6	27488.6	2146.5	2016.3	8024.6	2055.0	1081.2	6072.8	4397.7	2127.4	1072.2	1134.6	15803.7	5572.2	1063.6	1786.6	52416.4	686.0	12389.5	3393.7	543.6	898.4	2506.7	2039.0	448.4	3091.4	177.3	373.4	569.1	300.0	1461.0	730.0	185496.5	1109.3	531.7	3100.0	18417.8	195.2	1359.5	44320.0	81834.0	205181.0	353.9	365.3	5293.6	321.1	606.7	929.4	659.6	189.2	3224.8	1254.3	224.5	373.3	1173.5	1461.6	38794.8	448.9	1919.2	292.6	834.0	1942.7	3146.7	855.2	184373.6	13922.6	508.5	259.9	206.9	559.7	2285.4	1944.4	18006.3	2121.8	1315.7	1909.2	5012.0	6527.1	944.1	1354.2	429.7	2749.6	228.2	43270.0	10915.9	1052.3	248.5	4321.0	1323.5	9590.5	1323.4	4783.4	2452.7	13826.3	681.7	16520.2	77.1	271.6	1859.2	257.3	423.2	1565.6	3247.3	10923.4	3042.3	608.6	514.8	861.7	877.8	280508.9	1526.0	717.8	8097.8	788.2	12769.2	465.8	25254.2	3779.6	187.8	613.9	589.0	304626.0	297519.1	508.6	1521.9	8830.4	982.5	976.6	1409.2	1504.0	673.5	6675.4	894.8	1083.1	112882.1	1166.8	939.0	1418.0	21091.2	685.7	1215.1	1184.8	602.0	11009.9	257.3	919.3	2489.0	585.1	510.3	5964.4	598.5	3019.1	809.4	984.6	628.4	7379.4	735.5	305.8	929.5	13799.4	3495.5	1867.4	21805.7	767.9	3610.1	1881.1	21484.4	45261.6	305.8	136.3	1864.8	864.9	7639.2	66789.0	1014.0	41156.3	1420.6	526.8	550.5	6196.1	2612.1	5337.8	841.9	4499.9	3256.4	12627.2	9174.0	1794.4	1615.6	10055.0	15581.2	400.4	1243.6	12314.0	234.1	593.3	3810.7	1499.4	91994.2	1759.2	537.2	21393.2	330.4	460.4	1313.3	715.6	19891.7	114101.9	5068.3	428.2	3382.8	370.2	308.9	825.2	1366.6	3923.0	4137.0	1041.2	373.9	937.8	20801.4	6628.4	478.6	1713.4	17376.5	14031.7	1146.2	9658.7	370.6	3890.2	2619.3	639.5	5723.3	1210.4	1522.1	479.7	3330.4	283.7	271.8	2957.4	1174.8	7677.2	2893.6	947.2	1544.3	2391.7	10363.9	1401.2	196.5	1839.4	725.2	348.5	630.5	306.3	937.0	6115.7	6180.2	2110.8	1264.4	1375.3	4062.7	1699.4	9111.0	2976.1	9502.9	422.1	433.1	38336.9	1001.9	3570.4	907.7	4379.1	3094.9	876.0	1246.9	1918.8	1177.1	4334.8	684.2	640.7	8757.9	817.9	4769.0	1809.7	1644.1	375.1	1223.4	1600.2	176.0	2689.3	3729.5	63962.7	217.3	8105.0	1886.8	1306.1	11279.4	2539.4	946.0	593.2	2825.0	1103.0	69899.9	19064.5	473.4	177.5	3286.1	131610.7	880.8	3374.5	2916.1	514.2	1188.0	4544.4	390.3	371.4	1433.7	1227.1	246.2	238.9	3937.0	2592.2	1034.1	6824.6	20700.7	6608.7	287.5	212.7	732.1	1375.4	1600.4	19865.9	1242.1	650.2	106702.1	463.1	1816.8	2577.6	416.9	833.7	2471.6	904.1	246.3	394.5	6614.6	210.6	10230.6	921.7	712.7	329.7	5927.3	3075.2	2259.8	3427.2	526.5	2540.5	605.0	557.1	433.1	6370.9	175.1	2404.1	70837.8	2327.6	11728.1	4586.5	6754.8	411.4	1324.5	13186.9	749.5	12288.6	41909.9	2831.2	322.0	3130.8	6943.6	9015.0	1771.0	316.2	344.9	49324.8	1958.9	676.5	202.9	1775.9	2830.5	541.2	721.8	1708.1	6701.3	2950.1	248.8	4726.9	7930.2	261.4	260.5	1002.0	168.4	179.8	706.0	49629.9	101.0	2437.7	2236.2	12082.7	6811.7	5844.2	14137.5	1596.2	548.1	664.1	270.0	228.8	22365.8	193.2	3833.0	1065.3	2211.8	1212.6	389.4	1087.4	467.7	6595.6	2173.2	463.4	1524.5	13490.3	675.0	5954.8	1583.3	7481.7	1499.0	18424.2	3016.0	1276.8	2306.5	2889.2	749.0	2402.5	4133.9	8706.8	1146.1	1477.7	1287.9	1127.3	2282.0	3085.0	980.7	2355.3	699.1	5034.8	1641.6	2651.2	1851.2	6519.4	7777.3	586.3	605.3	7578.1	1237.7	36963.8	8780.0	1189.9	1340.2	9260.0	12643.9	2348.8	21446.1	1360.2	533.5	351.7	2156.7	212.0	811.8	1334.8	747.3	538.3	344.2	2090.4	1092.7	6831.0	2107.7	1750.7	3256.9	674.1	152.5	29461.3	1813.2	668.4	413.3	221.5	872.8	382.5	3906.4	926.4	2067.7	3651.6	1236.0	588.1	389.9	766.3	8428.4	478.5	494.3	284.8	615.9	1107.9	3957.0	70143.8	1549.8	4329.7	38311.3	309.7	11422.1	3139.4	941.6	2248.5	532.8	549.0	724.2	136.6	5310.4	611.8	731.0	6072.6	1872.5	745.4	339.5	214.1	345.7	569.3	1438.3	8100.0	603.1	656.0	393.2	241.8	1097.9	8701.1	1317.2	224.2	3123.9	4996.7	2052.6	325.0	222.8	9873.8	826.0	706.4	83259.4	345.8	29548.8	266.5	13902.7	796.5	281.0	320.5	8841.8	276.1	366.1	409.4	22458.7	176.3	6218.5	412.2	473.2	268.0	244.3	29812.3	17729.6	730.4	4137.5	25000.4	7940.4	24274.7	21639.5	247.9	734.5	2177.3	65700.8	8420.3	224228.3	2231.8	417.2	1987.8	247.9	4982.2	1413.5	3249.6	201.1	5150.3	10996.3	471.7	1051.2	1039.6	2540.4	933.8	9381.7	2765.6	1611.6	417.9	13957.2	214.4	458.0	5862.1	170.7	270.6	686.1	226.8	232.5	409.4	6884.8	3501.1	230.9	547.5	1249.1	306.9	2680.6	4735.0	2823.9	562.4	291.4	18412.8	3087.9	9289.0	1576.5	167.7	65395.8	1416.8	10903.9	643.3	64465.4	4553.3	2155.0	5338.1	1838.2	325.3	252.5	949.5	243.9	273.6	178.7	10635.5	52237.2	3124.5	471.9	1133.9	328.3	410.5	11883.1	12238.5	1168.6	4814.8	416.6	417.8	1116.5	141.4	239.5	1143.8	1374.1	566.3	115.8	18312.8	580.8	7427.1	178.0	2306.5	968.1	15512.8	5805.8	14205.6	153723.7	441.9	1359.5	803.3	2206.8	274.7	32392.7	2288.2	13351.6	8632.5	3340.6	414.2	2726.2	12770.0	529.1	7454.5	1009.5	309.7	9737.1	645.1	1603.4	691.1	341.7	10251.1	636.6	842.4	762.2	313.4	713.1	146.2	7517.2	540.5	840.0	1993.8	6616.7	2517.7	368.8	1435.4	401.5	746.1	284.3	484.0	2883.7	2030.8	5216.5	2879.7	3487.1	2463.8	23208.3	35783.5	195.7	2896.7	1809.2	1089.4	671.0	6188.8	1224.6	1902.1	1057.3	41343.2	2538.1	707.8	6135.1	1323.5	3919.5	1446.1	618.4	596.3	974.5	673.8	1207.8	503.0	3717.3	12636.6	6308.3	3128.0	123.7	1107.0	261.3	395.8	1468.8	396.9	763.5	326.5	1468.0	63651.6	16494.9	1383.6	566.6	791.6	2978.0	4243.4	32048.7	683.1	790.8	801.4	847.9	127778.5	519.7	11448.3	1069.7	557.1	2285.1	3065.4	2200.2	673.9	1276.8	921.4	4451.1	5348.4	6041.5	1277.2	16852.8	2086.8	4592.0	1767.7	10122.6	255.2	7303.6	509.7	3026.9	2198.2	6415.9	324.1	27481.6	10603.4	1288.8	1387.7	358.0	291.6	957.7	75340.6	1430.6	1195.6	32340.6	206.7	268.8	1002.2	1501.6	368.3	140570.0	1201.6	7100.4	1241.3	817.6	732.9	595.8	1207.9	50160.2	867.8	462.1	10445.3	2018.3	1216.1	867.9	420.3	606.1	139.0	951.0	1669.8	11030.8	971.5	1550.7	431.2	5235.0	1541.4	5724.3	240.0	520.7	980.6	4771.1	496.7	1913.0	738.8	903.1	790.1	160.0	357.0	5784.2	605.9	26229.7	1024.8	405.9	30624.0	2083.3	5005.4	822.1	1288.6	260.9	2178.8	4433.9	239.0	4673.3	13959.2	741.3	453.9	461.1	889.3	315.4	1245.3	358.0	11268.3	1172.9	1187.3	1106.5	2769.1	2279.7	935.6	29297.9	600.9	17751.1	942.6	1482.3	2571.2	1239.5	3826.5	3429.8	455.2	2880.0	10338.9	1194.0	18991.4	393.0	9681.7	253.5	1254.3	1620.6	1294.1	16117.9	192.3	5210.3	6773.4	383.3	364.9	1684.4	1556.8	581.7	6435.9	348.8	577.2	2751.6	193.3	1479.0	556.5	1390.2	412.2	530.8	551.2	2374.7	32894.5	1223.4	2266.7	5805.4	2849.7	4687.6	1772.1	2080.1	609.4	1315.6	1461.5	4844.9	1647.4	4565.6	2607.3	1792.5	2416.9	44953.1	918.4	4206.5	7450.6	6508.8	1616.0	11403.1	8065.1	434.6	316109.5	4317.0	158956.9	211.1	2927.8	877.2	4685.6	4015.1	1970.7	15417.8	735.9	484.3	3142.5	1919.6	2168.9	702.5	8727.9	1038.8	543.0	1104.4	1001.3	9962.6	896.1	6479.9	2304.1	630.7	2165.9	1957.8	2210.0	1153.4	11779.0	4767.2	5586.9	1477.8	10073.3	35378.8	8847.6	536.1	604.7	19604.3	825.9	4634.1	2309.9	3716.7	1851.8	298.6	921.2	12148.7	3161.8	23480.3	1150.3	85170.1	2868.5	674.8	372.4	18321.1	570.3	325.5	22236.3	895.8	1824.2	43915.8	26504.7	3356.0	1907.0	691.6	572.0	3137.2	611.6	1008.5	587.8	879.1	419.4	2050.6	601.8	1080.7	553.3	9721.9	265.9	3837.1	1027.2	592.5	415.8	268.1	6189.0	421.5	2523.9	677.0	170.2	70848.9	3322.3	52085.0	774.0	3759.4	1892.4	729.8	996.8	17046.7	377.5	944.3	1282.9	465.8	271.4	708.5	281.3	1367.5	58935.9	761.7	691.2	156.2	5213.3	1375.9	1499.4	821.6	1904.6	5031.5	833.8	549.9	533.6	899.5	5940.5	11218.0	48362.4	5701.4	2095.5	27688.4	354.7	835.9	296.8	4155.0	26508.4	263.6	4160.1	366.6	1163.7	722.0	5656.6	822.4	155.8	1037.4	9465.8	626.3	1927.6	7697.9	431.6	1074.6	1331.6	1321.5	407.6	2511.0	3030.9	775.4	1104.2	1127.0	1308.8	277.7	439.5	1137.3	1298.4	1909.2	529.8	860.1	380.2	7069.7	523.6	1875.9	10159.0	3421.6	2124.9	1001.5	3324.6	74437.7	2615.5	17126.6	1314.1	5311.1
PDMZ724XCN	PD	UTSW	80.0	180	29	Male	Set.5	761.1	814.6	25208.0	757.3	1550.8	977.3	3801.8	7159.7	913.5	411.2	419.9	10308.4	8550.0	1762.1	1527.9	248.3	6783.4	376.5	1963.4	1653.3	446.7	2442.2	2547.6	1507.2	1881.3	372.9	297.2	2461.5	4283.9	34780.1	25891.2	30079.2	600.1	2317.0	10272.6	971.2	452.9	434.9	1554.3	1319.2	2165.3	420.9	571.9	691.4	40721.6	7536.8	2221.4	2077.7	1344.3	1247.3	5465.5	1731.3	42213.3	10559.8	1939.8	1001.9	1933.7	4293.3	4616.3	29482.8	8392.7	6726.3	87707.7	3649.9	165.4	528.8	1596.3	7620.6	1609.9	6090.4	2342.5	2296.8	1292.0	1079.6	509.8	439.5	1802.7	10226.0	655.9	849.5	305.9	24035.3	1070.4	9267.8	2714.9	357.4	15084.8	888.7	13140.2	651.2	1443.9	945.7	509.2	903.3	1820.6	2757.3	10843.8	867.2	981.3	4053.5	344.1	1704.6	1068.9	92153.1	87.2	667.6	217.8	501.1	1399.1	8333.5	6313.3	21120.8	964.3	3266.7	903.3	20477.5	187.0	812.1	310.0	247.8	157.3	38861.0	13526.2	1210.7	631.6	75102.3	932.6	973.1	6219.0	30058.5	4587.0	16328.7	1096.3	46448.8	924.9	1046.1	6250.8	15303.3	788.8	12830.6	404.9	545.8	198.8	665.9	1167.0	1552.5	2889.1	750.3	1094.6	2434.0	5126.4	591.2	276.8	165.5	372.7	7333.7	383.6	494.9	1968.7	5018.3	26169.3	1150.6	531.2	2917.1	1484.0	1857.3	6286.2	12777.7	155.9	536.3	8462.4	30210.4	25324.2	815.1	10661.9	558.1	12920.7	2183.8	6199.7	9024.7	3965.5	28158.6	549.4	28359.5	1666.5	23433.0	8255.3	1778.7	904.5	3965.4	4288.4	2048.6	965.5	278.6	28724.2	4109.3	971.5	2668.5	39853.6	688.8	9912.7	4915.7	522.6	966.0	2131.8	2890.7	668.4	2742.4	174.6	304.3	577.6	260.9	1406.0	954.7	225041.8	1060.1	3114.3	4022.9	11631.0	181.1	1543.1	41248.7	63631.0	202897.4	278.7	287.6	7611.8	443.6	579.2	752.2	1459.7	152.2	2753.8	1784.5	204.4	369.1	903.1	713.8	30568.9	467.6	1835.3	259.9	372.7	2064.3	6031.7	688.2	185710.7	8258.2	941.8	273.9	196.0	688.6	2492.9	2460.7	16262.7	1681.0	1692.9	1728.8	4143.0	5052.2	784.9	1716.8	313.6	3544.9	248.1	20747.4	12425.7	823.2	416.7	3999.9	1177.0	8886.8	1508.4	5682.1	2696.5	11998.1	578.2	19207.9	74.9	188.5	1681.4	232.4	447.0	1431.6	2905.9	15442.1	2695.7	594.1	502.5	1186.6	850.9	327807.9	1492.8	671.0	5574.8	807.3	8164.6	426.3	24874.2	4179.9	177.4	537.8	1194.3	159053.4	197336.0	460.0	1430.3	10938.3	1609.2	895.0	1366.5	1082.1	484.1	5971.9	800.3	607.1	117258.5	1176.1	922.2	904.7	16281.8	1009.7	1221.9	1239.1	790.6	10887.6	250.6	1154.2	2545.6	627.1	1548.7	4798.2	574.9	2244.8	596.7	1080.5	585.7	10128.2	291.7	243.0	814.1	6393.8	3540.9	2041.6	7917.9	605.1	3458.3	2284.2	299.5	44033.9	307.1	106.5	1735.5	1201.7	13003.4	96937.5	1279.5	47342.3	543.2	777.0	548.3	5246.5	2388.5	2392.7	1320.7	4455.6	2848.3	25614.1	7844.7	1750.6	1041.0	5660.8	4951.2	555.7	422.8	36692.5	217.1	534.8	4815.8	1907.9	99798.0	2727.0	734.2	25608.2	420.0	3329.1	2354.9	602.7	13963.4	126039.3	4421.8	368.3	3237.8	418.8	295.3	1093.6	1030.0	4493.4	4908.9	1199.2	374.1	862.6	19792.9	1641.1	513.3	1434.9	19351.1	22078.3	1102.8	4212.9	362.2	3005.1	2389.1	641.6	5854.9	1040.8	2343.9	649.8	2890.5	231.1	207.4	995.8	1160.1	5937.0	5975.0	924.9	1222.7	4020.0	7426.0	1078.9	164.4	1897.6	1344.4	397.2	558.8	236.6	1534.4	2481.3	5107.1	2811.4	873.5	1270.3	7550.6	8691.6	8299.8	3859.4	7247.2	593.0	352.7	39532.1	2769.2	2675.4	691.7	3604.5	5133.1	690.0	1533.0	2008.8	1370.5	4134.9	511.0	608.5	7749.9	487.7	2905.6	1906.8	1494.0	320.5	1372.5	1490.9	469.0	3238.5	4748.0	59435.8	220.2	7813.7	2381.1	3117.1	11208.6	2975.5	706.5	4986.7	3296.6	1218.2	66886.9	31545.3	579.4	137.9	3223.8	117956.0	795.8	4837.2	1758.6	546.8	1240.6	5739.7	538.0	346.1	1383.4	1237.9	14970.6	188.4	3734.5	5052.3	1200.1	6572.7	14437.8	5929.3	264.2	191.4	1108.1	975.3	1778.1	32363.1	1159.7	555.2	100116.8	533.9	1819.5	3613.7	192.0	1629.9	4973.6	786.7	185.8	313.7	1493.1	204.7	15567.6	883.6	778.8	950.8	7806.3	5211.3	2323.3	3390.0	1350.7	2291.8	561.6	439.6	378.0	10229.0	159.8	1177.4	53078.1	2381.1	12629.6	3295.3	8210.4	2913.3	1265.3	10876.5	748.4	13611.0	31796.9	3183.0	350.3	5092.5	5680.9	2721.9	1727.4	1111.6	638.8	23501.9	2273.1	545.3	171.2	2898.2	3370.0	437.6	1496.7	5615.2	5285.3	2218.7	206.5	3937.8	7820.0	204.7	228.9	853.2	154.4	150.4	1322.1	26171.8	120.2	2222.2	1278.1	4889.4	4784.4	8467.9	12305.9	1869.3	480.2	727.8	275.6	260.9	26519.5	242.8	5758.6	1137.5	1836.9	1385.3	458.8	1579.5	567.6	4712.2	8716.9	430.9	4041.4	14120.4	607.1	4499.3	1749.0	9703.6	1361.0	23022.7	2642.1	2487.8	2994.1	1654.7	842.3	2636.2	3649.5	5879.9	1041.4	2139.0	1212.5	1654.1	2394.6	2879.9	888.5	1799.8	757.9	9910.4	1236.9	2491.7	2418.1	4888.3	5794.2	456.4	591.7	7043.3	1147.1	38674.0	8530.9	1158.2	1396.8	8708.2	14697.2	2641.1	19073.0	183.3	756.4	949.9	1863.6	226.3	652.2	1255.0	768.7	396.3	290.5	1789.0	1567.9	4490.9	1837.2	1567.6	2096.2	821.3	275.4	9105.4	1591.2	925.0	685.4	241.7	880.0	482.6	5860.2	608.8	2443.6	4091.1	500.9	809.8	404.7	1261.3	5585.0	446.0	520.7	223.0	591.2	3200.6	4329.8	97272.1	1556.8	4512.9	58562.0	434.5	14035.0	3964.2	1079.6	3610.2	905.7	466.6	873.4	143.2	7312.3	1016.1	1586.8	8742.5	2148.9	764.6	405.8	280.0	434.9	283.2	5246.9	10107.1	538.6	873.9	346.6	234.4	926.6	15658.2	1626.7	448.1	3396.7	7479.0	2668.1	446.0	185.6	8302.6	245.1	310.6	96471.5	333.6	32013.7	244.9	4405.2	884.1	247.6	457.5	411.4	261.0	297.1	337.2	14142.2	167.9	2401.9	322.6	462.8	188.2	218.2	23297.1	29420.4	682.9	3407.6	20406.4	6729.5	18640.3	35987.1	285.1	1574.6	2010.8	67736.6	11057.4	242452.5	1661.6	353.6	2778.0	251.3	6007.1	2207.5	3848.6	247.6	7641.8	10919.5	542.3	1318.3	1948.1	2384.4	2428.7	9016.2	3991.2	1578.0	417.1	24778.5	205.9	494.2	12903.4	415.0	359.1	844.9	158.3	255.1	421.8	15706.2	2351.2	267.3	594.6	2836.8	321.7	3466.5	6397.6	3576.8	534.5	228.4	26134.3	4581.4	16375.3	3303.1	164.1	30177.8	1669.6	11990.0	2253.6	98498.4	4404.0	2330.5	1972.7	2672.9	390.9	224.2	1059.0	292.9	308.5	173.4	8885.9	29316.0	2897.0	485.6	1095.2	303.5	355.2	12658.2	7726.2	1072.7	4411.8	414.0	450.3	1109.6	120.9	246.8	1276.0	2505.0	767.1	130.6	14316.0	530.2	5334.9	4059.3	2315.1	860.4	15701.1	12120.2	21222.6	135355.3	443.1	1569.2	781.3	2875.5	272.8	27559.0	2753.1	15608.8	16166.1	1804.3	334.6	1846.4	13291.1	442.3	7589.3	1106.3	330.9	18476.5	462.6	993.0	629.9	461.0	15787.7	563.6	660.2	798.7	319.8	972.6	142.8	5921.0	488.2	765.5	361.1	7093.8	3219.0	391.9	2620.9	381.0	596.6	320.3	422.5	4081.3	2323.1	5547.0	1253.3	3132.8	3088.9	12764.8	29713.2	166.2	2867.0	3308.4	490.5	765.8	4364.3	749.6	750.0	759.7	54303.4	3589.6	1023.3	4045.0	1255.4	5234.2	1572.5	763.7	627.5	819.2	659.5	1302.4	762.8	3215.2	12164.6	5139.6	2040.7	157.0	616.3	233.8	423.4	3060.2	402.0	1228.4	882.2	2421.7	68908.3	16535.4	2216.3	481.8	926.2	6775.7	3600.1	40852.2	847.2	1140.9	6508.9	2607.0	134210.3	508.7	11579.3	900.7	977.8	3551.6	2698.3	2351.6	814.3	1597.5	995.5	6613.4	7620.0	4747.7	1484.7	111800.3	1842.7	4526.8	3284.9	6408.5	223.3	5209.2	201.4	9283.7	2480.6	6302.7	356.1	12126.5	7790.1	3245.9	2246.5	356.0	292.7	17871.6	74373.0	1252.2	780.7	28108.3	260.7	281.5	1110.9	4279.4	420.1	158171.2	1077.5	8648.6	7757.9	674.1	799.6	1144.8	1388.4	37465.5	1316.1	678.1	9369.2	2991.7	1292.0	775.2	660.4	479.2	224.8	1248.7	5569.2	13264.4	1324.7	1404.1	418.0	3288.8	863.9	5499.4	156.5	484.7	1001.4	1881.1	675.2	1478.5	1674.7	1006.1	795.8	152.4	359.9	4746.1	525.4	22243.8	706.2	419.6	21937.2	2320.1	5877.7	1166.5	1360.3	255.9	3910.1	2424.9	1299.2	3959.7	10232.0	579.6	621.8	452.2	484.1	321.5	344.6	362.7	9501.7	387.7	1104.0	921.5	2687.1	2303.5	555.3	25836.2	730.9	25328.2	2359.6	1070.0	3047.5	1217.1	3129.7	4254.8	356.6	6413.1	14344.3	2036.3	10185.9	410.8	9821.7	251.9	1265.8	1764.8	1423.1	17293.5	300.7	5931.1	8913.7	356.8	344.2	1208.2	1847.8	537.9	8259.2	442.0	2225.2	3201.8	276.5	1583.9	577.1	1105.0	332.7	693.0	480.3	876.6	56095.1	1042.3	3033.3	5933.9	9179.1	3496.4	1837.4	2352.5	2367.4	798.7	1323.7	13064.8	1915.8	1802.5	1505.8	1659.7	2908.1	526.9	674.2	5148.0	10496.1	7615.2	870.0	12839.7	8878.3	391.1	245759.1	3535.8	157310.0	207.8	8706.9	934.7	3529.8	3513.5	2148.6	20748.6	1521.4	461.9	2849.5	1809.3	2375.1	583.6	7333.6	859.5	530.2	855.0	734.4	9351.7	1406.1	8586.1	2124.7	532.3	2694.3	1587.7	2353.8	2398.6	12446.5	3805.4	6807.3	1247.0	9732.9	31426.7	5800.7	971.0	905.9	18874.9	1574.9	4186.6	3094.5	1924.9	2438.1	215.3	950.5	26628.7	2498.2	32597.0	1431.1	94172.4	5557.3	519.3	1217.0	63193.3	991.8	256.1	24293.2	672.0	1584.2	240950.5	33190.2	4637.5	1982.3	747.0	694.5	2807.9	720.4	717.8	808.6	864.1	478.5	3531.9	688.3	1394.3	501.7	10210.4	286.6	571.0	1660.6	359.0	518.6	259.2	4128.1	385.5	2434.5	780.4	185.9	118511.0	5475.6	61405.5	1157.1	4770.6	1628.5	396.5	4291.8	20230.0	393.9	1306.9	1469.2	509.8	471.1	864.2	252.6	982.6	16659.3	550.3	1027.9	260.7	5637.2	1473.0	1661.9	1103.3	1050.0	4434.9	610.0	486.9	9658.2	1148.9	3406.2	12591.1	29705.5	2522.7	25830.1	62536.7	324.0	1055.9	254.0	5537.1	21346.5	325.9	658.8	403.5	1460.0	751.4	2617.8	1625.1	178.5	838.8	12882.0	1135.3	2088.3	9952.2	441.2	1156.0	804.2	1776.1	335.8	3063.1	1680.9	678.7	1177.7	1351.7	845.1	167.7	436.3	3051.4	1785.0	2141.3	747.4	577.4	403.1	10035.3	604.5	1916.9	5151.1	4430.8	2404.4	1386.6	1178.9	59023.4	2009.1	6272.7	1185.3	5964.7
PDMH749VDY	PD	UTSW	66.8	15	50	Male	Set.4	921.9	852.0	30894.8	693.5	1429.2	1527.1	1139.3	3838.6	1882.2	301.3	329.7	12523.5	9029.6	1119.1	2022.5	190.2	13219.1	404.2	2181.1	1058.1	239.5	2066.5	919.8	430.3	2281.4	321.0	242.7	1490.9	9001.1	5842.0	39645.7	31187.1	740.3	2003.0	5482.4	897.8	417.3	369.2	1518.3	1172.0	1294.5	257.2	522.1	456.7	29765.2	8790.3	2011.4	1306.5	1282.6	1215.9	3912.3	1479.7	31896.3	11034.5	1093.8	887.8	2666.4	3460.5	7345.6	18393.0	5298.5	5586.0	37756.5	2545.3	142.7	455.3	1250.3	9892.8	1722.1	3820.7	1794.3	1508.9	1018.6	898.0	398.6	390.6	994.1	20008.9	477.7	291.3	186.4	13262.8	955.2	9795.3	2821.2	334.4	8850.3	907.5	12152.4	605.6	1161.9	734.8	430.8	709.8	1850.7	1989.9	15305.5	896.3	825.0	4282.3	79.7	860.9	1034.1	49830.1	48.4	681.0	167.0	311.9	1163.3	7723.4	8325.1	56980.8	861.1	3107.1	700.7	12643.7	211.7	769.4	241.1	239.2	116.8	41600.3	10743.8	1404.6	483.9	64320.1	734.4	767.1	4600.9	25291.4	4610.4	17710.7	1257.4	42869.4	1856.2	779.3	6589.4	15148.7	909.6	9985.5	281.6	340.5	180.9	567.5	857.8	402.2	1793.2	534.6	1008.7	1871.0	3160.6	420.0	338.7	147.5	509.2	7739.5	336.2	397.6	2077.0	6261.5	36372.7	1142.1	471.4	2801.8	2209.6	1358.2	7339.7	8369.5	193.1	526.4	14543.7	30998.8	40378.8	651.8	13169.1	839.2	8308.2	953.4	8015.4	13246.3	3671.5	47108.4	761.6	34915.2	2216.3	13675.9	8335.0	2016.6	590.6	3629.7	2244.9	2129.0	942.3	229.1	27881.7	5352.6	1262.0	1451.2	45716.5	704.9	7795.9	3617.1	279.7	647.1	2443.8	2372.6	153.3	4444.7	140.5	282.8	589.7	155.5	1454.1	1484.9	218880.7	1077.9	486.5	6289.9	16233.1	189.2	1538.1	38494.6	61257.9	177988.1	279.5	284.8	11147.5	582.0	710.9	723.2	2034.6	141.3	3674.6	1596.5	157.5	306.1	488.8	487.6	38797.4	449.7	1508.4	230.7	587.0	2423.8	9057.1	744.1	183081.0	19280.9	433.2	250.9	148.8	601.7	1948.9	1982.0	11831.6	2087.3	1914.5	1677.2	3008.3	5597.2	525.2	757.7	237.2	3009.2	298.5	14602.6	11046.8	815.3	263.9	3902.2	1486.8	9351.0	1561.8	5093.6	2530.9	7676.9	476.9	26936.5	53.4	194.4	2043.5	227.7	442.4	1343.3	2704.3	28204.0	2822.6	522.8	1816.3	1483.0	938.5	301444.4	1587.6	622.1	9381.7	754.0	6614.1	423.8	34802.5	2409.7	143.8	696.2	997.3	303553.9	294340.4	436.9	2194.1	17352.3	819.5	613.7	953.9	1328.3	541.4	4976.1	1052.3	1980.6	97529.5	1223.5	794.2	1773.1	12726.4	766.1	1103.1	1838.9	646.7	9136.9	250.1	1220.5	2651.7	897.7	462.9	3423.6	453.3	3157.2	692.7	795.3	493.8	11934.6	324.7	252.4	814.5	6813.3	3262.6	1399.1	29782.2	427.7	3038.4	2343.4	16335.7	22579.6	280.3	92.4	1717.6	643.7	7075.3	47882.9	1844.9	52627.5	5799.5	363.1	1960.9	7416.6	1862.2	1926.1	502.1	4524.0	1416.1	27463.0	3548.0	1459.5	757.4	11188.2	8629.7	1053.0	435.8	17872.9	191.1	345.4	4265.4	977.4	73501.1	1993.8	475.7	23169.7	330.6	812.1	1939.4	543.4	10070.4	96248.2	5765.3	294.5	1906.9	286.4	250.7	799.4	926.3	6059.5	4268.6	1019.6	286.0	740.0	7810.6	3354.5	352.0	1634.6	22833.9	21058.1	866.5	4336.7	288.6	4894.9	2671.7	545.1	10620.4	875.6	1566.3	360.2	2995.5	221.7	180.9	716.2	1229.3	8055.5	2940.1	877.3	1375.9	3952.0	5915.6	1072.2	144.8	2355.3	992.6	246.8	492.2	215.5	1897.5	5926.0	6489.7	2492.0	1488.5	1196.2	7243.4	1459.3	6900.8	1909.5	8719.6	586.6	333.6	51829.4	2701.9	1436.5	713.9	4421.5	4356.5	521.0	470.8	2273.0	1145.5	4619.9	1088.8	11792.3	7792.4	415.0	37.8	3010.9	1737.1	234.4	1433.2	1022.8	125.7	3107.6	5564.9	59137.8	182.2	7632.0	1918.3	2296.5	10015.2	2355.1	950.2	435.3	1687.4	879.5	70660.4	11449.4	327.5	133.7	6153.3	126557.3	735.9	6320.4	4958.1	677.2	1529.1	5396.6	304.3	303.4	1416.1	1282.7	349.7	195.3	2862.1	7297.7	1585.9	5703.4	11237.7	6167.8	212.5	180.4	391.5	1843.1	1567.5	34710.9	1309.4	590.0	95759.0	617.8	2084.8	4987.4	191.0	923.1	5692.7	788.0	189.1	310.9	1398.4	202.8	18691.4	978.0	863.9	264.7	4029.1	8277.6	2056.0	4415.5	2437.1	2005.4	558.7	443.2	385.3	10756.9	149.1	1482.8	54772.2	3910.3	5100.8	2551.6	11918.6	911.3	688.1	11776.8	630.5	9985.1	38702.7	2977.0	282.4	5539.4	5573.4	2805.2	1563.7	1697.6	649.7	19401.0	2091.1	548.8	170.1	2748.6	2477.9	375.5	2300.0	6268.5	5421.6	1464.5	176.8	1874.3	11532.0	200.2	188.9	1572.3	143.0	153.5	1079.8	30651.3	93.4	1932.2	849.0	3678.8	6071.3	6494.6	13578.2	1351.9	480.8	354.1	244.0	223.4	24168.7	250.6	3768.2	951.4	2212.3	1327.6	360.0	1099.8	554.5	6676.3	13600.4	324.4	2101.0	13214.1	489.9	6006.7	1305.6	4750.4	1243.8	26459.2	2519.4	1751.7	2775.7	1216.7	641.8	2700.4	4212.3	6671.8	1024.2	1651.3	1087.1	1315.7	2673.1	2846.9	737.5	1434.5	581.4	7268.3	1140.1	2849.7	3243.5	5401.2	8496.8	350.3	521.8	7888.5	927.3	45651.7	9160.2	778.6	1218.4	9410.6	14180.0	2786.4	24719.2	459.7	604.4	424.5	1171.2	207.9	468.8	1103.7	611.7	368.6	279.4	1982.9	1461.8	3825.6	1226.6	1243.0	1571.8	458.9	121.9	16043.4	1474.2	614.2	448.2	226.2	718.7	348.3	4142.4	725.5	2533.8	8198.0	433.5	1272.5	291.9	1148.4	14112.9	364.2	447.5	262.0	545.0	4031.4	4593.9	121162.2	3644.4	3415.6	75730.5	480.0	17262.1	3816.5	1328.0	5093.9	521.8	583.8	807.8	152.3	12371.9	761.4	2313.3	10248.5	3082.2	935.8	359.5	258.4	384.3	320.7	7362.6	12142.3	530.6	922.5	313.8	195.4	872.5	6304.3	2069.6	311.4	3179.4	10104.2	3759.0	367.1	165.4	7483.5	486.1	646.7	100999.7	283.9	27690.3	253.8	6555.3	598.6	196.7	298.1	636.0	201.0	230.0	329.5	23677.4	135.1	2106.1	380.3	367.2	252.5	198.8	8605.7	27622.0	759.0	4274.7	27261.2	7177.6	19248.3	31992.0	197.9	1231.6	2042.2	60662.1	8733.8	236859.9	1548.7	333.5	3975.2	217.9	8922.9	2683.8	2933.7	159.0	9531.6	19031.8	417.6	1617.3	2416.7	2627.0	3217.1	9062.0	7118.2	1426.3	386.7	35021.7	186.3	421.6	19284.8	348.8	260.3	1332.7	146.0	199.0	378.6	20179.9	4156.6	215.0	632.7	3932.1	278.5	5372.2	8985.4	1557.2	540.5	207.1	38551.0	7281.0	12676.5	4356.6	125.5	28559.4	1528.6	14769.3	870.5	22016.8	1886.4	1870.7	1974.5	1291.7	408.7	195.3	1507.6	264.3	241.4	132.8	3468.5	35464.2	3140.2	447.6	1261.6	249.9	240.1	12605.5	8703.2	1158.4	4157.0	390.5	321.8	1267.1	107.4	169.1	1108.5	1559.5	804.2	100.2	12660.8	492.6	4884.9	2325.9	2391.0	869.1	15753.1	10347.0	12299.5	101780.1	577.7	1391.2	752.2	1515.6	245.5	25868.9	733.9	13069.5	16396.4	4213.6	289.9	1599.0	11850.2	463.1	6708.1	1110.0	339.2	23846.3	451.3	907.3	685.3	529.0	11505.7	599.7	604.1	782.2	260.8	1020.0	129.6	7656.0	489.5	859.9	300.8	3372.1	1986.3	357.2	3292.3	311.9	519.8	220.7	312.3	3405.3	1579.6	5850.0	1111.6	2728.9	3536.2	9423.6	30947.7	171.1	3203.4	3046.3	724.7	488.5	4718.8	604.1	1070.6	623.4	38227.3	1829.4	524.7	3963.7	987.9	2916.1	2048.1	1481.0	504.6	1009.5	466.9	1149.2	500.3	2760.9	10691.2	6599.5	2762.8	119.0	699.9	207.2	410.3	1255.8	286.1	1990.0	255.8	2726.1	68920.0	15612.0	1789.9	438.2	1192.3	5580.8	2704.0	16009.6	846.9	417.7	692.4	783.9	101724.4	379.8	10490.1	516.1	703.0	3222.7	3874.1	1228.2	812.4	1316.3	773.6	4699.7	7152.4	2998.6	1835.1	148685.8	1610.1	4877.7	670.9	5400.9	227.4	5209.9	166.4	7370.3	3197.5	5248.4	266.9	7729.7	4050.6	2199.8	876.6	275.8	169.4	561.5	73744.0	1451.3	495.3	23181.8	149.9	252.4	1130.6	5271.4	379.7	151829.2	1057.8	8603.0	885.4	533.1	797.8	489.2	2022.4	54118.4	829.6	883.5	13555.8	4675.6	882.5	912.8	332.0	415.5	243.6	1263.9	2898.8	19159.3	1446.1	1754.4	344.1	4136.5	967.0	5061.6	122.6	375.3	888.7	4002.0	352.6	1557.8	842.7	1018.8	714.5	125.9	289.8	3299.8	596.4	13414.7	575.7	310.4	15086.9	1291.6	4723.9	788.5	1273.5	247.8	2360.1	2611.4	431.9	4781.6	10120.7	603.5	759.0	441.1	1444.2	163.5	507.7	293.0	8125.7	418.3	396.9	809.2	1887.2	1321.4	503.6	25805.7	507.0	20239.2	583.7	628.2	2373.3	908.1	1947.4	3101.5	382.8	5327.1	16514.9	1141.1	17930.2	363.0	6115.9	194.5	758.1	1355.0	977.8	6622.3	134.9	3284.5	3827.9	300.1	320.0	1066.5	2721.2	325.3	13575.0	240.9	642.0	5793.5	303.3	1386.5	620.3	1304.4	331.2	458.9	553.0	981.8	72788.2	974.2	3496.8	5678.5	16971.2	3954.9	2060.5	2699.5	529.5	740.3	892.2	17124.1	1600.5	1462.2	1576.5	1356.8	2086.1	396.5	572.4	7873.2	9091.8	7644.6	817.9	6064.6	7868.9	303.0	338214.3	4315.2	170736.2	182.6	7667.7	1138.0	3680.8	3327.1	1806.6	15622.9	3455.0	400.7	1826.6	1689.3	2070.0	487.4	3026.9	685.1	436.4	917.4	618.5	9048.9	627.9	13348.6	1766.9	645.8	2201.7	1730.5	1582.6	1784.1	6985.2	3992.5	7308.4	1027.7	9385.7	12181.6	10045.5	431.4	747.3	15976.6	1430.3	7780.1	3000.7	1563.0	3379.6	202.5	575.2	33272.7	2995.4	39679.7	845.7	83564.2	8090.0	389.4	252.2	65949.1	833.7	237.2	21177.7	514.3	1523.3	73586.7	49985.2	6692.2	2167.0	1377.9	653.6	3179.0	505.1	1029.0	671.4	584.0	281.3	2836.5	538.4	1225.5	392.0	8330.9	225.0	516.8	2315.9	285.3	416.6	184.0	4572.8	501.9	2457.6	656.8	151.0	145295.5	5225.8	70513.0	1008.3	6636.2	1477.9	414.1	5527.6	29187.4	267.8	1107.6	1458.7	616.7	205.1	972.2	210.3	1012.3	48683.0	398.4	780.0	172.2	4840.1	1327.8	1986.3	901.8	1069.4	4304.1	474.3	509.8	408.9	1115.3	1728.5	10941.8	40670.5	2443.0	12175.6	82715.0	180.9	920.4	175.7	10818.4	18072.9	260.7	449.4	255.6	1022.4	813.7	2642.6	605.8	141.0	551.2	6588.4	780.6	1106.7	4953.1	430.6	1364.5	784.4	2309.1	384.6	2479.0	1877.3	507.1	1231.2	1147.0	917.5	148.8	371.7	2106.2	1843.0	3443.1	855.5	398.8	374.1	9137.6	600.3	1367.2	3835.4	4662.8	5474.4	941.0	2956.1	45611.9	3550.2	24817.0	1357.4	4979.6
PDKL402HA0	PD	UTSW	63.0	NA	27	Male	Set.1	12915.0	919.1	20305.6	782.0	1639.4	1189.1	1178.1	7281.8	966.4	324.1	524.4	12789.0	8731.8	1412.0	1423.2	243.8	6966.0	458.4	2363.7	1193.7	241.3	2345.8	5116.8	510.0	1894.6	290.7	320.4	1925.4	5461.4	10430.0	31878.2	40533.5	601.7	1563.1	3572.7	1000.4	512.2	455.6	1580.2	1359.3	1382.5	587.7	534.6	596.3	31850.2	17044.8	2060.1	1419.7	1253.6	1370.8	5309.5	1758.9	39534.3	3902.0	1346.6	360.8	2478.0	3386.8	6247.1	21657.6	6106.4	6328.7	97343.7	2727.1	127.1	1099.4	1322.3	5704.0	1857.8	5934.2	1674.1	1547.4	1302.9	894.0	640.8	425.1	1204.7	28274.0	696.4	349.5	214.2	12836.9	1027.0	15200.8	2407.1	368.9	11341.4	813.7	17867.5	715.7	1260.5	732.9	490.1	836.5	1296.6	2554.1	12223.5	903.8	1377.5	6913.1	374.7	1569.8	1348.6	80178.1	65.0	592.6	166.7	502.9	1327.5	9183.8	7158.8	24784.6	756.2	3586.4	925.1	10705.8	301.8	799.6	238.4	284.0	131.0	35615.6	12619.6	913.3	515.1	88140.9	936.5	1062.1	6577.2	40665.3	4896.0	18399.4	1082.4	39634.9	1919.8	867.0	8411.9	19599.7	1588.4	10788.4	302.2	420.7	117.2	607.0	912.3	693.6	2308.9	639.5	912.7	1745.9	3602.8	486.6	346.6	153.5	535.2	7487.6	383.8	579.9	2170.1	5390.2	49529.7	1230.7	548.3	2898.5	3047.1	1430.3	7540.2	14281.8	188.3	1502.2	4286.4	37483.6	33134.9	771.5	11937.8	632.7	11126.4	1069.6	7081.1	12926.7	3240.0	27018.9	1201.3	32894.4	1349.2	11644.0	4657.1	2391.7	687.4	3425.2	1838.0	2377.0	1069.4	282.9	17479.6	4452.8	1089.3	1720.7	45568.5	688.5	11422.7	5260.3	339.6	889.0	2410.3	2263.2	550.2	3217.9	145.3	298.9	812.9	194.7	1343.0	1572.1	231213.0	1138.9	484.7	4153.2	22619.0	262.6	2278.2	38145.7	47610.7	163380.8	456.6	415.3	11651.2	645.9	1236.9	1051.0	1468.3	308.5	3372.9	1445.2	361.5	303.2	708.8	1927.5	48426.0	820.4	1712.5	434.7	412.0	2826.7	5274.4	883.0	170458.9	8620.0	464.9	438.6	266.2	492.3	2352.9	2152.5	12542.8	1991.6	3941.1	1783.7	3008.0	6357.0	659.4	1219.2	316.9	2492.3	229.5	20701.2	10295.2	1132.2	264.7	3967.4	1131.1	9587.7	1416.8	3813.0	2799.0	7424.7	586.6	17949.7	64.1	194.7	1900.1	281.1	839.1	1523.3	3375.5	18676.2	2904.7	470.9	455.7	1176.3	912.9	299167.3	1666.1	663.8	5696.5	960.2	5195.8	443.4	17943.8	3025.2	297.3	731.2	562.8	180334.0	207934.3	492.5	2550.8	11554.0	788.4	722.7	1071.1	1360.1	630.2	5455.3	1040.0	502.3	111842.4	1810.8	730.6	959.1	13105.8	697.1	1394.7	1447.9	2865.3	8006.1	382.7	1300.1	2538.3	837.6	480.5	3445.8	509.2	2625.2	390.5	773.1	573.5	12404.1	1070.0	302.8	731.5	8433.3	2810.5	1731.7	9053.8	495.8	4531.6	2468.7	20070.7	29858.8	281.3	98.6	2199.6	1278.4	7535.9	75282.8	1210.9	52735.7	352.0	1537.1	491.0	8564.5	2719.9	2391.9	661.4	4000.1	4413.2	10320.5	3501.3	1657.3	1262.1	12519.2	8376.0	480.8	398.5	24823.9	325.8	462.2	6539.6	1290.3	69252.6	3043.2	552.5	16453.5	483.7	2505.2	1614.2	644.7	12029.5	96411.1	5949.7	329.4	2444.4	320.4	421.2	750.0	1843.6	4989.4	4734.2	935.8	295.4	1174.6	10437.6	5633.9	431.9	1429.4	20068.9	15033.0	1067.4	9273.3	339.9	3022.8	2242.0	734.0	5486.6	900.3	1599.8	716.1	2868.7	258.5	212.3	1477.1	1150.1	6399.9	2133.0	1285.1	1654.5	3701.5	6763.7	1240.5	152.4	2134.7	706.8	280.3	507.7	222.4	2008.2	6347.2	6500.9	1535.3	1120.4	1851.2	5212.7	1911.1	9472.8	2451.9	7514.2	389.2	371.8	48674.3	2243.9	3327.5	732.6	4782.1	2961.7	727.8	1528.1	1860.5	1427.3	5442.9	735.0	625.4	10748.2	394.6	48.3	753.4	1921.1	1705.3	1180.7	968.0	321.6	3607.0	5144.1	55420.4	213.9	8297.0	2366.8	2496.6	9324.7	2365.6	905.4	386.1	2530.9	1143.8	62041.8	10683.6	527.8	140.4	4477.8	147437.8	819.4	5628.1	3683.2	900.9	2560.5	10404.9	358.2	321.7	1636.2	1299.1	191.7	219.3	2856.0	4945.6	1558.4	7888.3	15720.1	5315.4	226.0	174.6	528.2	1731.2	1320.7	38511.7	1198.8	638.8	103542.9	618.8	2126.1	3921.2	182.5	981.7	4375.7	822.3	226.8	513.9	2654.1	236.7	14037.0	971.5	1580.2	269.3	2896.8	5305.9	2855.7	7499.7	1219.9	2327.0	709.6	510.9	992.6	8311.6	134.8	1334.5	51634.2	2620.0	6517.4	3188.7	9738.1	633.9	802.0	9546.1	944.8	7646.5	41367.4	2724.1	290.8	5767.9	5411.3	7775.2	2524.2	1180.8	612.2	20099.8	4758.5	604.1	183.2	1542.6	3533.5	445.3	1905.7	3722.2	4849.3	1734.5	196.8	3336.7	9167.7	268.2	205.7	1368.3	165.8	151.1	1253.1	13153.0	210.7	2226.4	1185.8	4259.3	6223.6	5509.9	15218.8	1012.2	451.6	580.5	241.5	224.5	15481.2	421.9	4084.5	1049.5	1877.0	2348.4	414.1	1453.8	577.2	6463.1	6012.3	408.1	2333.9	13716.8	589.1	5465.7	1441.8	6437.5	1692.0	20716.6	2635.2	2089.0	2252.0	4362.7	2914.9	2613.5	4311.4	7545.0	965.1	1734.2	1259.1	1306.6	2556.9	2906.5	921.1	1179.9	796.8	6104.2	1292.1	2856.4	3104.5	4289.1	6808.2	1014.8	589.1	7231.5	1151.3	40430.7	8702.2	863.4	1266.3	10171.6	10263.0	2900.7	19742.3	490.3	1288.7	355.1	2352.7	214.6	528.6	1373.5	642.7	394.8	295.2	2175.7	2058.6	4925.6	1512.7	1771.3	3072.9	1728.1	141.6	14829.9	1319.2	681.9	929.7	230.2	1879.6	381.2	7324.7	862.3	3344.7	6067.2	9908.5	923.5	310.6	1006.9	5588.1	351.1	932.8	197.3	461.0	2637.6	5683.5	76628.8	1650.6	9091.0	60915.0	547.0	17348.8	4451.4	1082.3	3680.9	1157.4	518.2	743.5	146.3	8857.6	750.5	1914.3	8397.4	2150.7	923.7	378.8	243.7	352.0	301.1	4508.7	14256.7	541.0	1057.3	366.6	346.3	1593.4	11472.7	1748.9	267.0	3088.8	12543.6	2698.1	344.4	289.5	8746.5	363.6	350.9	94280.0	305.7	24896.5	253.8	5881.0	1759.1	197.5	262.2	947.9	199.6	389.0	341.6	15300.6	191.4	1718.0	531.6	457.9	190.7	201.2	16820.6	18008.1	702.0	3671.7	25360.8	7839.9	10992.2	29138.2	214.5	1343.4	2371.2	53468.6	11126.1	250305.5	2319.2	327.0	2696.0	206.6	8041.3	1738.7	2741.4	176.7	7072.4	17050.9	482.4	1742.8	2609.5	2389.6	2187.0	8711.9	6350.8	1504.3	382.1	25652.1	202.3	511.3	12957.3	347.5	261.5	977.2	167.3	199.9	483.4	15083.0	3498.7	229.0	547.7	3015.0	286.4	4195.1	6907.0	2173.3	525.4	223.8	27708.7	4822.3	14127.8	3482.5	169.2	24381.9	1289.0	11957.8	258.1	13876.0	3817.9	2130.0	2269.1	1289.2	353.8	227.0	1188.9	257.4	243.8	162.1	7831.0	36717.5	2366.1	431.3	1184.3	429.1	302.2	20286.0	11752.2	1174.1	6418.3	361.4	373.9	1103.0	111.6	203.2	1072.5	2606.1	1040.9	140.0	17298.0	550.9	4900.4	161.7	2591.7	949.6	16853.7	10372.6	10518.6	108185.7	515.3	1224.2	725.9	2578.1	294.4	21348.8	1058.3	20412.9	6975.5	2099.1	316.1	1808.3	13195.0	430.9	7136.0	1264.1	4462.3	13754.0	550.8	1594.7	672.5	324.6	11948.0	745.1	665.9	1000.4	270.1	857.5	105.4	6647.0	519.3	806.7	308.7	5305.2	2396.0	375.4	2455.7	369.4	595.9	250.9	936.6	3234.5	1668.3	5455.9	1732.7	3692.2	3130.7	10517.5	41770.3	172.2	3715.5	2272.9	882.4	608.6	5698.0	940.6	622.0	1080.6	37009.1	2720.1	677.3	5458.6	1576.8	10246.7	2127.6	1209.0	805.3	1076.8	467.0	1388.2	508.3	4540.3	12477.9	6362.0	3007.0	269.2	481.7	291.9	797.9	4023.6	649.9	1007.4	449.6	2694.1	72478.7	13368.5	1541.2	468.6	855.0	4150.4	36907.7	30452.5	614.2	753.6	2513.0	819.6	135225.5	432.7	14669.7	770.2	589.8	2569.2	1733.0	1787.4	918.0	2346.1	1123.5	5560.3	5955.4	4720.7	1746.3	126924.2	1689.3	5539.0	870.7	5890.5	182.5	5176.3	168.5	4577.3	3145.1	4757.1	311.1	15587.3	5113.6	2495.5	794.8	347.2	303.1	2226.2	61663.0	1596.6	717.9	28930.6	410.4	245.2	1165.3	6003.9	394.3	159140.4	1032.5	8980.6	3555.2	631.6	727.0	600.2	1903.9	59557.5	1096.7	458.3	11777.5	3478.2	1194.9	867.6	1057.4	464.4	453.2	1366.0	2228.3	17654.8	1142.0	1848.6	422.6	2514.0	968.2	7376.5	188.2	456.1	1007.0	4546.8	361.4	1906.5	816.1	1061.5	816.8	131.5	390.3	3754.7	559.0	17364.9	1859.1	400.1	15782.8	1563.2	4921.9	1145.4	1562.6	262.2	2433.4	3523.3	309.5	4307.1	9304.0	671.1	287.1	432.2	822.1	819.6	369.1	573.5	8617.2	367.0	866.7	1050.5	2856.0	2147.9	501.9	27976.2	1025.0	22859.1	1881.0	1117.8	2541.7	1469.3	2642.0	3855.8	434.8	3709.2	14831.0	1018.1	24557.5	406.7	7091.8	496.3	810.5	1564.4	1005.2	7771.8	152.9	3882.9	6581.1	978.2	323.7	1242.6	1969.3	585.1	8483.5	738.7	757.3	4431.9	564.9	1890.6	615.0	1139.7	353.5	660.8	3472.7	677.0	50224.5	1129.4	3774.1	5334.8	9186.5	4058.4	2017.9	2669.2	939.1	2211.1	1261.7	12178.0	2325.4	1465.9	1720.2	1496.2	2505.3	442.3	780.8	6428.8	10135.6	10464.7	1101.3	10801.6	8969.7	382.7	265036.0	4446.1	189670.5	181.4	2861.5	1145.7	3248.7	3393.2	2954.0	17181.3	2021.9	386.1	2167.9	1566.6	1886.0	619.8	3223.4	803.8	665.2	778.0	688.2	10977.1	722.9	9408.6	5200.6	610.4	2670.4	1826.8	1617.7	1367.8	8236.5	4517.7	7604.5	1097.9	10922.3	15271.4	9862.6	574.8	713.6	17356.7	1056.6	9446.3	3481.3	1467.7	2932.1	467.0	919.1	25312.2	2726.8	33141.2	1341.1	99060.1	5162.6	498.5	280.8	18728.4	1037.6	261.2	23626.9	590.9	1570.7	73288.5	49618.6	5028.2	2276.0	1120.4	756.5	2845.2	717.8	806.8	888.0	925.9	341.7	3227.2	834.4	1277.7	649.5	9556.1	243.7	2652.7	905.8	345.2	477.8	176.1	4963.6	747.2	2240.9	653.8	198.1	125876.8	5636.7	71704.2	890.3	5332.0	1256.9	516.6	2922.8	21107.1	324.1	1125.7	1614.3	538.6	202.1	1145.1	262.6	2654.5	37750.6	470.3	698.0	159.1	2993.8	1749.3	1921.8	1010.3	1158.9	3796.4	489.2	557.4	490.1	1055.7	2387.4	15029.2	26496.8	3119.1	4920.6	64432.2	332.8	988.1	256.7	5973.7	26731.5	221.0	941.2	313.1	1332.2	741.2	5543.7	768.3	169.6	598.4	6438.5	741.4	1248.5	2742.5	452.3	1089.5	801.3	2160.3	355.9	3621.8	1118.4	649.5	1226.7	1660.0	1315.5	181.0	400.1	1850.7	1776.9	2972.3	702.9	478.9	369.0	10087.9	579.3	1637.2	3761.6	3774.6	3493.2	811.7	1302.9	52761.7	2777.9	8551.4	1169.2	5494.1

# Let's extract the columns that include proteine expression only
protein = df[9:1313]
# Let's first normaliz the dataset using log10 transformation
protein.log = log10(protein)
# Let's first do some quality control analysis to identify potential outliers
dat.pca <- prcomp(protein.log,cor=F)
protein.log$Site = df$Site
autoplot(dat.pca)

# Based on the PCA plot,looks like there's one significant outlier. let's remove that outlier before further analysis
protein.log = protein.log[-309,]
df = df[-309,]
#Now, we can add clinical variables back to the pre-processed protein values
protein.log$GUID = df$GUID
protein.log$Group = df$Group
protein.log$Site = df$Site
protein.log$Age = df$Age
protein.log$LDOPA = df$LDOPADoseTm
protein.log$UPDRS = df$UPDRS

Differential Expression Analysis

Now, let’s move on to compare the proteomic expression level difference betwen normal control and Parkinson’s patients

setwd('/Users/junchaoshen/UPenn BMI')
library(GEOquery)
library(oligo)
library(limma)
library(viridis)
library(GEOquery)


design <- model.matrix(~ -1 + factor(protein.log$Group))
colnames(design) <- levels(factor(protein.log$Group))
fit <- lmFit(t(protein.log[,1:1305]), design)
fit.contrast <- makeContrasts(diff = Control - PD, 
                                  levels = design)
fit2 <- contrasts.fit(fit, fit.contrast)
fit2 <- eBayes(fit2)
exposure_results <- topTable(fit2, coef = "diff", adjust = "BH", num = Inf)
exposure_results[exposure_results$sig == 'significant',]

## [1] logFC     AveExpr   t         P.Value   adj.P.Val B        
## <0 rows> (or 0-length row.names)

library(ggplot2)
library(ggrepel)
# Assign (in)significant genes
exposure_results$sig <- rep("insignificant", nrow(exposure_results))
exposure_results$sig[which(exposure_results$adj.P.Val<0.05)] <- "significant"
v1 = ggplot(exposure_results, aes(x = logFC, y = -log10(adj.P.Val), color = sig)) + 
  geom_point() +
  theme_bw() +
  ggtitle("Volcano plot") +
  xlab("LogFC")+
  ylab("-Log10(q-value)") +
  scale_color_manual(values = c("black", "red")) +
  theme(legend.position = "none")

v1+geom_text_repel(data=head(exposure_results, 40), aes(label=rownames(exposure_results)[1:40]))

dict = read.csv('Protein Demographic.csv',skip = 1)

dict1 = t(dict[4:5,])[-1:-8,]
rownames(dict1) = NULL
colnames(dict1) = c('SYMBOL','Protein.Name')
exposure_results$Protein.Name = rownames(exposure_results)
protein_gene = merge(exposure_results,dict1,by = 'Protein.Name')
DE_res = protein_gene
write.table(exposure_results, "./Protein_DE_results.txt", row.names = F, 
            col.names = T, quote = F, sep = "\t")

df_boxplot1 = data.frame(
  expression = protein.log[,'BSP'],
  status = protein.log$Group)

ggplot(df_boxplot1, aes(x = status, y = expression)) +
  geom_boxplot(outlier.colour = NA, color = "grey18", fill = "lightblue") +
  stat_boxplot(geom = "errorbar", color = "grey18") +
  geom_jitter(size = 1, position = position_jitter(width = 0.3)) +
  ggtitle("BSP Expression Level between PD and Control") +
  xlab(" ") +
  ylab("BSP Expression Level (RFU)") +
  theme_bw() +
  theme(legend.position = "none")

df_boxplot2 = data.frame(
  expression = protein.log[,'OMD'],
  status = protein.log$Group)

ggplot(df_boxplot2, aes(x = status, y = expression)) +
  geom_boxplot(outlier.colour = NA, color = "grey18", fill = "lightblue") +
  stat_boxplot(geom = "errorbar", color = "grey18") +
  geom_jitter(size = 1, position = position_jitter(width = 0.3)) +
  ggtitle("OMD Expression Level between PD and Control") +
  xlab(" ") +
  ylab("OMD Expression Level (RFU)") +
  theme_bw() +
  theme(legend.position = "none")

df_boxplot3 = data.frame(
  expression = protein.log[,'ApoM'],
  status = protein.log$Group)

ggplot(df_boxplot3, aes(x = status, y = expression)) +
  geom_boxplot(outlier.colour = NA, color = "grey18", fill = "lightblue") +
  stat_boxplot(geom = "errorbar", color = "grey18") +
  geom_jitter(size = 1, position = position_jitter(width = 0.3)) +
  ggtitle("ApoM Expression Level between PD and Control") +
  xlab(" ") +
  ylab("ApoM Expression Level (RFU)") +
  theme_bw() +
  theme(legend.position = "none")

library(gplots)
# keep top 200 genes
top_results <- subset(exposure_results,sig =='significant')
top.eset <- protein.log[colnames(protein.log) %in% row.names(top_results)]
status.colors <- unlist(lapply(protein.log$Group, 
                               function (x) {if (x == "PD") "red"  
                                 else "navy"}))
heatmap.2(t(top.eset), col = viridis(256, option = "B"),
          trace = "none", keysize = 1.5, key.title = NA,
          ColSideColors = status.colors)
legend("topright", legend = c("PD","Control"), fill = c("red", "navy"))

library(fgsea)
kegg <- gmtPathways("./c2.cp.kegg.v7.4.symbols.gmt")
reactome <- gmtPathways("./c2.cp.reactome.v7.4.symbols.gmt")
pathways <- c(kegg, reactome)
head(DE_res)

##   Protein.Name        logFC  AveExpr          t      P.Value  adj.P.Val
## 1         ABL1  0.016198841 2.148463  0.9153406 0.3607002121 0.59373515
## 2         ABL2 -0.007336859 3.245519 -0.7138443 0.4758423919 0.68920568
## 3         ACE2  0.007742940 2.755534  0.4798996 0.6316257721 0.79677100
## 4         ACTH  0.006590667 2.650429  0.3888161 0.6976700768 0.83479717
## 5       ADAM12  0.002574039 2.663372  0.1578207 0.8746973233 0.93334438
## 6  Adiponectin -0.091616177 3.555267 -3.8473203 0.0001440704 0.01216739
##           B           sig SYMBOL
## 1 -6.087681 insignificant   ABL1
## 2 -6.248323 insignificant   ABL2
## 3 -6.385116 insignificant   ACE2
## 4 -6.423896 insignificant   POMC
## 5 -6.485802 insignificant ADAM12
## 6  0.594801   significant ADIPOQ

library(dplyr)
DE_res <- DE_res %>%
  filter(!is.na(SYMBOL)) %>%
  group_by(SYMBOL) %>%
  arrange(P.Value) %>%
  filter(row_number() == 1) %>%
  data.frame()

gene_list <- DE_res$t
names(gene_list) <- DE_res$SYMBOL
gene_list <- sort(gene_list, decreasing = T)
head(gene_list, 5)

##      PRL       C3   UBE2G2      CRP      LPO 
## 4.278304 3.613029 3.579063 3.476249 3.343124

options(warn=-1)
fgseaRes <- fgsea(pathways = pathways, stats = gene_list, minSize = 15, 
                 maxSize = 500, nperm = 10000, gseaParam = 1)
fgseaRes <- fgseaRes[order(fgseaRes$pval), ]

collapsedPathways <- collapsePathways(fgseaRes = fgseaRes[padj < 0.05], 
                                      pathways = pathways, stats = gene_list)
mainPathways <- fgseaRes[pathway %in% collapsedPathways$mainPathways] # keep results of independent pathways

top_pathway <- mainPathways %>%
  filter(padj < 0.05 & abs(NES) > 1) %>%
  arrange(NES)

top_pathway$pathway <- factor(top_pathway$pathway, levels = top_pathway$pathway)
ggplot(top_pathway, aes(y = NES, x = pathway)) +
  geom_bar(width = 0.8, position = position_dodge(width = 0.8), stat = "identity", fill = "blue") + 
  coord_flip() +
  theme_bw() +
  theme(
    axis.title.y = element_blank()
  )

plotEnrichment(pathway = pathways[["KEGG_CHEMOKINE_SIGNALING_PATHWAY"]], stats = gene_list) + 
  labs(title="KEGG_CHEMOKINE_SIGNALING_PATHWAY")

top_pathway %>% 
  filter(pathway=="KEGG_CHEMOKINE_SIGNALING_PATHWAY") %>% 
  dplyr::select(leadingEdge) %>% 
  unlist() %>% 
  unname()

##  [1] "CCL22"  "CCL27"  "CCL5"   "CSK"    "RAC1"   "MAPK1"  "STAT1"  "STAT3" 
##  [9] "PRKACA" "CRK"    "LYN"    "VAV1"   "CCL18"  "CCL17"  "FGR"    "SHC1"  
## [17] "PIK3CG"

Classification Model of the Disease (PD vs Normal)

Let’s train the model using top 8 proteins + clinical variates like age + sex + disease duration

setwd('/Users/junchaoshen/UPenn BMI')
library(caret)
library(e1071)
library(precrec)
library(ROCit)

utsw = protein.log[protein.log$Site == 'UTSW',]
penn = protein.log[protein.log$Site == 'PennState',]


### Let's train the model using 4 proteins that passed the p value threshold of 0.05 on both cohorts
train_control <- trainControl(method = "repeatedcv", number = 5, repeats = 50)
model <- train(as.factor(Group) ~
                        Age+
                        ApoM+
                        BSP+
                        OMD+
                        NCAM.120+
                        IDS+
                        IGFBP.2+
                        FCN1,
                        method = "glm",
                        data = utsw,
                        na.action=na.omit,
                        family = binomial)

# Let's take a look at the final model
summary(model)

## 
## Call:
## NULL
## 
## Deviance Residuals: 
##     Min       1Q   Median       3Q      Max  
## -2.5302   0.2372   0.3796   0.6345   1.3347  
## 
## Coefficients:
##              Estimate Std. Error z value Pr(>|z|)   
## (Intercept) -24.71861   12.36014  -2.000  0.04551 * 
## Age           0.02957    0.02906   1.017  0.30894   
## ApoM         -1.80507    2.10129  -0.859  0.39032   
## BSP           1.94530    1.82972   1.063  0.28770   
## OMD          -1.10608    2.30227  -0.480  0.63092   
## NCAM.120      3.75151    3.49502   1.073  0.28310   
## IDS           1.11857    2.29752   0.487  0.62636   
## IGFBP.2       4.52205    1.63369   2.768  0.00564 **
## FCN1         -0.90673    2.16967  -0.418  0.67601   
## ---
## Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
## 
## (Dispersion parameter for binomial family taken to be 1)
## 
##     Null deviance: 128.28  on 139  degrees of freedom
## Residual deviance: 107.55  on 131  degrees of freedom
## AIC: 125.55
## 
## Number of Fisher Scoring iterations: 5

# Plot ROC curve with AUC score
options(repr.plot.width=8, repr.plot.height=8)
predict_train1 <- predict(model, newdata = utsw, type= "prob")
predict_test1 <- predict(model, newdata = penn, type= "prob")
precrec_obj1 <- rocit(class = utsw$Group, score = predict_train1$PD)
precrec_obj2 <- rocit(class = penn$Group, score = predict_test1$PD)
plot(precrec_obj1,col = 'Red')

plot(precrec_obj2,col = 'Blue')

summary(precrec_obj1)

##                            
##  Method used: empirical    
##  Number of positive(s): 116
##  Number of negative(s): 24 
##  Area under curve: 0.7809

summary(precrec_obj2)

##                            
##  Method used: empirical    
##  Number of positive(s): 100
##  Number of negative(s): 79 
##  Area under curve: 0.5989

Longitudinal Analysis

MoCA ~ Top 20 proetins quartile X Days from Baseline + Age + Sex + Disease Duration

library(sjPlot)
library(sjmisc)
library(nlme)
library(lme4)

Longitudinal = read.csv('UTSW MoCA Longitudinal Final.csv')
kable(Longitudinal[1:5,], "html") %>% kable_styling("striped") %>% scroll_box(width = "100%")

GUID	YearstoVisit	MoCATotal	MoCA_BL	Group	SampleDate	AgeAtSample.x	DiseaseDuration	Sex	a1.Antitrypsin	a2.Antiplasmin	a2.HS.Glycoprotein	a2.Macroglobulin	ABL1	ACE2	ACTH	Activated.Protein.C	Activin.A	Activin.AB	ADAM.9	ADAM12	ADAMTS.4	ADAMTS.5	Adiponectin	Afamin	Aflatoxin.B1.aldehyde.reductase	Aggrecan	AIF1	AIP	AK1A1	Albumin	ALCAM	ALK.1	ALT	Aminoacylase.1	AMNLS	AMPK.a1b1g1	AMPK.a2b2g1	AMPM2	amyloid.precursor.protein	AN32B	Angiogenin	Angiopoietin.1	Angiopoietin.2	Angiopoietin.4	Angiostatin	Angiotensinogen	ANGL3	ANGL4	annexin.I	annexin.II	annexin.VI	Antithrombin.III	Apo.A.I	Apo.B	Apo.D	Apo.E	Apo.E3	AREG	ARGI1	ARI3A	ARMEL	ARP19	ARSB	ART	Artemin	ARTS1	Arylsulfatase.A	ASAH2	ASAHL	ASGR1	ASM3A	ATS1	ATS13	ATS15	AURKB	Aurora.kinase.A	Azurocidin	b.ECGF	b.Endorphin	b.NGF	b2.Microglobulin	B7.2	B7.H1	B7.H2	BAFF	BARK1	BCAM	Bcl.2	BCL2.like.1.protein	BCMA	BDNF	bFGF	BFL1	BGH3	BGN	BLC	BMP.1	BMP.7	BMP.RII	BMPER	BMPR1A	BMX	BNP.32	BOC	Bone.proteoglycan.II	BPI	BSP	BSSP4	BST1	BTK	C1.Esterase.Inhibitor	C1r	C2	C34.gp41.HIV.Fragment	C3d	C5	C5a	C5b.6.Complex	C7	C8	C9	Cadherin.2	Cadherin.5	Cadherin.E	Calcineurin	calgranulin.B	Calpain.I	Calpastatin	CAMK2A	CAMK2B	CAMK2D	CaMKK.alpha	CAPG	Carbonic.anhydrase.6	Carbonic.anhydrase.9	Carbonic.anhydrase.I	carbonic.anhydrase.II	Carbonic.anhydrase.III	Carbonic.Anhydrase.IV	Carbonic.anhydrase.VII	Carbonic.Anhydrase.X	Carbonic.anhydrase.XIII	Caspase.10	Caspase.2	Caspase.3	Catalase	CATE	Cathepsin.A	Cathepsin.B	Cathepsin.D	Cathepsin.H	Cathepsin.S	Cathepsin.V	CATZ	CBPE	CCL28	CD109	CD22	CD226	CD23	CD30.Ligand	CD36.ANTIGEN	CD40.ligand.soluble	CD48	CD5L	CD70	CD97	CDC37	CDK1.cyclin.B	CDK2.cyclin.A	CDK5.p35	CDK8.cyclin.C	CDON	CFC1	Chitotriosidase.1	Chk2	CHL1	CHST6	cIAP.2	Ck.b.8.1	CK.BB	CK.MB	CK.MM	CK2.A1.B	CK2.A2.B	CLC1B	CLC4K	CLF.1.CLC.Complex	CLM6	CNDP1	CNTF	CNTFR.alpha	CNTN2	CO8A1	Coagulation.Factor.IX	Coagulation.Factor.IXab	Coagulation.Factor.VII	Coagulation.Factor.X	Coagulation.Factor.XI	Cofilin.1	Collectin.Kidney.1	COMMD7	complement.factor.H.related.5	CONA1	contactin.1	Contactin.4	Contactin.5	COX.2	CPNE1	CRDL1	Cripto	CRK	CRP	CRTAM	CSF.1	CSK	CSK21	CTACK	CTAP.III	CTGF	CTLA.4	CXCL16.soluble	Cyclin.B1	Cystatin.C	Cystatin.M	CYTD	CYTF	CYTN	Cytochrome.c	Cytochrome.P450.3A4	CYTT	DAF	DAN	DAPK2	DBNL	DC.SIGN	DcR3	DEAD.box.protein.19B	DERM	DHH	discoidin.domain.receptor.1	Dkk.4	DKK1	DKK3	DLC8	DLL1	DLRB1	DnaJ.homolog	dopa.decarboxylase	DR6	DRAK2	DRG.1	DRR1	DSC3	Dtk	DUS3	Dynactin.subunit.2	ECM1	EDA	EDAR	EF.1.beta	EG.VEGF	eIF.5	eIF.5A.1	Elafin	Elastase	EMAP.2	EMR2	Endocan	Endoglin	Endostatin	Endothelin.converting.enzyme.1	ENPP7	ENTP5	Eotaxin	EP15R	EphA1	EPHA3	EphA5	EPHAA	EPHB2	EphB6	Ephrin.A4	Ephrin.A5	Ephrin.B3	EPI	Epithelial.cell.kinase	EPO.R	ER	ERBB1	ERBB2	ERBB3	ERBB4	ERK.1	ESAM	Esterase.D	ETHE1	FABP	FABPE	Factor.B	Factor.I	FAK1	FAM107B	Fas.ligand.soluble	FCAR	FCG3B	FCGR1	FCN1	FCN2	FCRL3	FER	FETUB	FGF.10	FGF.12	FGF.16	FGF.18	FGF.19	FGF.20	FGF.4	FGF.5	FGF.6	FGF.8A	FGF7	FGFR.2	FGFR.3	FGFR4	FGR	FLRT1	Flt.3	Flt3.ligand	FN1.4	Fractalkine.CX3CL.1	FSH	FST	FSTL3	Fucosyltransferase.3	FUT5	FYN	G.CSF.R	GA733.1.protein	Galectin.2	Galectin.3	Galectin.4	Galectin.8	GAPDH.liver	GCKR	GCP.2	GDF.11	GDF.9	GDF2	Gelsolin	GFAP	GFRa.1	GFRa.2	GIB	GIIE	GITR	Glucagon	Glutamate.carboxypeptidase	Glutathione.S.transferase.Pi	Glypican.3	GM.CSF	GNS	GOT1	gp130.soluble	GP1BA	GPC2	GPC5	gpIIbIIIa	GPNMB	GPVI	Granulysin	granzyme.A	Granzyme.B	Granzyme.H	GRN	Gro.a	Gro.b.g	Growth.hormone.receptor	GSK.3.alpha.beta	GV	H6ST1	HAI.1	Haptoglobin.Mixed.Type	Hat1	HCC.1	HCC.4	HCG	HCK	HDAC8	HDGR2	Hemopexin	Heparin.cofactor.II	HGF	HGFA	HINT1	HIPK3	Histone.H1.2	Histone.H2A.z	HIV.2.Rev	HMG.1	HMGR	hnRNP.A.B	hnRNP.A2.B1	hnRNP.K	HNRPQ	HO.2	HPG.	HPLN1	HPV.E7.Type.16	HRG	HSP.40	HSP.60	HSP.70	HSP.90a.b	HTRA2	HVEM	I.309	I.TAC	ICOS	IDE	IDS	IDUA	IF4A3	IFN.g	IFN.g.R1	IFN.lambda.1	IFN.lambda.2	IgD	IgE	IGF.I	IGF.I.sR	IGF.II.receptor	IGFBP.1	IGFBP.2	IGFBP.3	IGFBP.4	IGFBP.5	IGFBP.6	IGFBP.7	IgG	IgM	IL.1.R.AcP	IL.1.R4	IL.1.sRI	IL.10	IL.11	IL.12.Rb1	IL.12.RB2	IL.13	IL.13.Ra1	IL.15.Ra	IL.16	IL.17	IL.17.RC	IL.17.RD	IL.17.sR	IL.17B	IL.17B.R	IL.17D	IL.17E	IL.17F	IL.18.BPa	IL.18.Ra	IL.19	IL.1a	IL.1F7	IL.1Rrp2	IL.2	IL.2.sRa	IL.2.sRg	IL.20	IL.20.Ra	IL.22	IL.22BP	IL.23	IL.23.R	IL.27	IL.3	IL.3.Ra	IL.34	IL.4	IL.4.sR	IL.5.Ra	IL.6	IL.6.sRa	IL.7	IL.7.Ra	IL.8	IL22RA1	IL24	ILT.2	ILT.4	IMB1	IMDH1	IMDH2	ING1	Insulin	Integrin.a1b1	Integrin.aVb5	IP.10	IR	ITI.heavy.chain.H4	JAG1	JAG2	JAK2	JAM.B	JAM.C	JAML1	JNK2	K.ras	Kallikrein.11	kallikrein.12	kallikrein.13	Kallikrein.4	kallikrein.5	Kallikrein.6	Kallikrein.7	kallikrein.8	Kallistatin	Karyopherin.a2	Keratin.18	KI2L4	KI3L2	KI3S1	KIF23	Kininogen.HMW	KIRR3	KLRF1	KPCI	KPCT	KREM2	Ku70	KYNU	Lactoferrin	LAG.1	LAG.3	Lamin.B1	Laminin	Layilin	LBP	LCK	LCMT1	LD78.beta	LDH.H.1	LEAP.1	Leptin	LG3BP	LIF.sR	LIGHT	LIMP.II	LIN7B	Lipocalin.2	LKHA4	LRIG3	LRP8	LRRT1	LRRT3	LSAMP	Luteinizing.hormone	LY86	LY9	Lymphotactin	Lymphotoxin.a1.b2	Lymphotoxin.a2.b1	Lymphotoxin.b.R	LYN	LYNB	Lysozyme	LYVE1	M2.PK	Macrophage.mannose.receptor	MAPK14	MAPK2	MAPK5	MAPKAPK3	MASP3	MATK	MATN2	MBD4	MBL	MCP.1	MCP.3	MCP.4	MDC	MDHC	MDM2	MED.1	MEPE	Mesothelin	Met	METAP1	MFGM	MFRP	MIA	MICA	MICB	Midkine	MIF	MIP.1a	MIP.3a	MIP.3b	MIP.5	MIS	MK01	MK08	MK11	MK12	MK13	MMP.1	MMP.10	MMP.12	MMP.13	MMP.14	MMP.2	MMP.3	MMP.7	MMP.8	MMP.9	Mn.SOD	MO2R1	Moesin	MP2K2	MPIF.1	MRC2	MSP	Myeloperoxidase	Myoglobin	Myokinase.human	NACA	NADPH.P450.Oxidoreductase	NAGK	NANOG	NAP.2	NCAM.120	NCAM.L1	NCC27	NCK1	NDP.kinase.B	Nectin.like.protein.2	NET4	Neurotrophin.3	Neurotrophin.5	NG36	NID2	Nidogen	NKG2D	NKp30	NKp46	NLGNX	NMT1	Nogo.Receptor	NOTC2	Notch.1	NovH	NPS.PLA2	Nr.CAM	NR1D1	NRP1	NRX1B	NRX3B	NSF1C	NUDC3	NXPH1	OCAD1	Olfactomedin.4	OLR1	OMD	ON	OPG	OX2G	P.Selectin	p27Kip1	PA2G4	PACAP.38	PAFAH	PAFAH.beta.subunit	PAI.1	PAK3	PAK7	PAPP.A	paraoxonase.1	PARC	PARK7	PBEF	PCNA	PCSK7	PCSK9	PD.L2	PDE11	PDE3A	PDE5A	PDE7A	PDGF.AA	PDGF.BB	PDGF.CC	PDGF.Rb	PDK1	PDPK1	Periostin	PERL	Peroxiredoxin.1	Peroxiredoxin.6	Persephin	PESC	PF.4	PFD5	PGCB	PGP9.5	PGRP.S	PH	PHI	phosphoglycerate.kinase.1	PIGR	PIK3CA.PIK3R1	PKB.a.b.g	PKC.A	PKC.B.II	PKC.Z	Plasmin	Plasminogen	PLCG1	PlGF	PLK.1	PLPP	PLXC1	PPAC	PPase	PPID	PPIE	Prekallikrein	PRKACA	PRL	Prolactin.Receptor	prostatic.binding.protein	Protease.nexin.I	Protein.C	Protein.disulfide.isomerase	Protein.disulfide.isomerase.A3	Proteinase.3	PSA	PSA1	PSA2	PSA6	PSD7	PSMA	PSME1	PSME3	pTEN	PTH	PTHrP	PTK6	PTN	PTP.1B	PTP.1C	PYY	Rab.GDP.dissociation.inhibitor.beta	RAC1	RAD51	RAN	RANTES	RAP	Rb	RBM39	RBP	RELT	Renin	resistin	RET	RGM.C	RGMA	RGMB	ROBO2	ROBO3	ROR1	RPS6KA3	RS3	RS7	RSK.like.protein.kinase	RSPO2	RUXF	SAA	SAP	SARP.2	SBDS	sCD163	sCD4	SCF.sR	SCGF.alpha	SCGF.beta	SDF.1	sE.Selectin	SE6L2	Secretin	Semaphorin.3A	Semaphorin.3E	Semaphorin.6A	SEPR	sFRP.3	SGTA	SH21A	SHBG	SHC1	SHP.2	Sialoadhesin	sICAM.1	sICAM.2	sICAM.5	SIG14	Siglec.3	Siglec.6	Siglec.7	Siglec.9	SKP1	sL.Selectin	SLAF6	SLAF7	sLeptin.R	SLIK5	SLPI	SNAA	SOD	Somatostatin.28	Sonic.Hedgehog	SORC2	Sorting.nexin.4	SP.D	SPARCL1	Sphingosine.kinase.1	SPHK2	SPINT2	Spondin.1	SPTA2	sRAGE	sRANKL	SRCN1	SREC.I	SREC.II	SSRP1	ST4S6	Stanniocalcin.1	sTie.1	sTie.2	STRATIFIN	Stress.induced.phosphoprotein.1	STX1a	suPAR	TAFI	TAJ	TAK1.TAB1	TARC	tau	TBK1	TBP	TCCR	TCPTP	TCTP	TEC	TECK	Tenascin	Testican.1	Testican.2	TF	TFF3	TFPI	TGF.b.R.II	TGF.b.R.III	TGF.b1	TGF.b2	Thrombin	Thrombopoietin.Receptor	Thrombospondin.1	Thymidine.kinase	Thyroglobulin	Thyroxine.Binding.Globulin	TIG2	TIMD3	TIMP.1	TIMP.2	TIMP.3	TLR4.MD.2.complex	TNF.a	TNF.b	TNF.sR.I	TNF.sR.II	TNFSF15	TNFSF18	Topoisomerase.I	tPA	TPSB2	TPSG1	TRAIL.R4	transcription.factor.MLR1.isoform.CRA_b	Transketolase	TrATPase	Triosephosphate.isomerase	TrkA	TrkB	TrkC	Tropomyosin.1.alpha.chain	Tropomyosin.2	TRY3	Trypsin	Trypsin.2	TS	TSG.6	TSH	TSLP	TSLP.R	TSP2	TSP4	TWEAK	TWEAKR	TXD12	UB2L3	UBC9	UBE2N	Ubiquitin.1	UFC1	UFM1	ULBP.1	ULBP.2	ULBP.3	UNC5H3	UNC5H4	uPA	URB	Vasoactive.Intestinal.Peptide	VCAM.1	VEGF	VEGF.C	VEGF.sR2	VEGF.sR3	VEGF121	WFKN2	WIF.1	WNT7A	X14.3.3	X3HIDH	X4.1BB	X4.1BB.ligand	X41	X4EBP2	X6.Phosphogluconate.dehydrogenase	X6Ckine	XEDAR	XPNPEP1	XTP3A	YES	ZAP70
PDAG965NUZ	0	28	28	PD	BL	76.3	2	Male	3.107447	3.244623	3.257871	4.028018	2.138934	2.742804	2.661245	2.950121	3.539176	2.906281	4.115384	2.646991	2.233250	2.700098	3.743322	4.421191	3.873605	2.672929	3.522679	4.153757	3.689611	4.275760	4.250271	3.128238	3.580914	3.564678	2.226342	2.632255	4.088699	4.642884	4.448134	2.253822	3.461529	2.964495	2.074085	2.870930	4.301919	3.745403	2.615108	3.627642	3.959194	3.742851	4.175460	5.124240	4.220587	4.083058	3.691285	4.619448	5.412079	3.626422	3.360139	2.933588	3.555421	3.542850	2.934195	3.206502	2.708166	4.939658	3.170643	3.484043	3.974314	3.084719	3.624138	2.60206	3.441915	2.586362	2.872448	3.057324	2.489255	2.270912	2.908163	2.754195	3.232183	3.022799	3.010427	3.269746	3.134528	4.079601	3.255851	3.198272	3.297848	3.995745	3.174060	3.195401	3.056600	4.623084	3.385124	3.361369	3.473735	2.960756	2.703635	2.709015	2.962653	2.506505	2.776483	3.097708	3.595210	2.890141	3.563113	3.281056	4.029591	4.281095	4.118003	3.558589	3.430945	2.903036	3.907589	3.915131	3.848528	2.693903	3.264676	3.514335	4.914363	3.243137	4.045745	4.823241	3.417887	3.587442	4.796785	3.634437	3.317938	3.718377	4.231419	2.724849	2.946550	3.673638	3.059488	4.121750	2.375846	3.243137	3.294643	2.503382	2.814580	3.79563	3.612487	2.570076	4.334844	4.213696	2.625827	4.065587	3.290168	3.022305	3.055531	3.029871	3.107549	3.760762	3.221284	3.736898	3.698796	2.980594	2.954532	3.275219	3.305201	3.970147	3.143702	2.848559	3.452078	2.451172	3.262024	2.817235	2.882354	3.008600	3.105783	3.326929	3.775982	3.543820	3.438874	2.583085	4.175526	2.429914	2.374748	4.729247	2.851503	2.529302	2.722058	4.154512	2.758230	4.483590	2.257439	2.678973	3.642880	3.915088	2.342225	3.919225	3.077876	2.741309	3.795943	3.643008	2.541579	3.347642	3.192874	4.099570	3.873838	3.617231	3.161518	2.849296	2.508395	3.656778	2.825880	2.736556	3.560301	3.611936	3.332560	4.030158	4.300532	3.121396	3.085825	4.212105	2.879726	3.132804	4.715550	3.304857	2.067071	4.070396	2.972203	3.388918	4.088459	3.98200	2.915347	3.118430	3.399154	4.393017	4.275675	4.205226	2.992554	3.677698	3.632822	3.391641	2.757548	3.840495	3.575257	2.906119	2.570309	3.933184	4.589664	3.890583	3.209327	3.344196	3.526494	2.878292	2.503109	3.874296	3.641920	4.794521	2.485580	2.533263	2.742175	3.591309	3.128076	4.384705	3.173536	3.297323	2.838093	2.236033	3.128722	4.67242	3.934685	2.723045	3.574610	2.824841	3.161996	3.152625	4.710611	4.287889	3.681440	3.603437	3.994344	2.960614	3.603772	2.139564	2.899054	2.590396	4.268814	3.231699	3.221649	3.472522	2.966470	2.992421	3.453853	2.582631	2.888685	4.396806	2.635484	2.474944	2.221153	4.609417	3.679210	3.583754	3.510277	4.077793	2.949000	4.397676	4.627936	2.502017	3.392873	2.689930	2.351603	3.123198	2.451326	3.361388	3.047002	2.564074	3.894720	3.662890	2.368844	2.325516	3.541217	2.431203	3.706590	2.574263	2.418135	2.668759	2.649627	3.505069	3.338934	2.386677	2.959089	3.075182	3.855876	3.056905	3.699933	2.663889	4.925982	3.453318	2.885191	2.934549	3.793595	2.772395	4.081693	4.406629	2.978409	2.675870	2.701309	4.290909	2.830653	2.718419	5.083698	2.678791	3.071514	3.814261	2.773055	3.428588	3.023746	3.545851	2.977815	3.710033	2.856910	2.491782	2.876622	3.649646	3.346196	3.773574	3.023664	2.470410	3.444154	3.477541	3.816778	3.245044	2.201397	2.867055	3.247065	3.704005	4.217894	3.143296	3.342778	2.312600	2.380392	4.374937	3.937513	3.030883	2.851992	4.375397	2.540329	3.370402	3.881738	4.565699	2.569959	3.806899	4.36128	2.773347	2.812646	3.376194	2.854670	2.997561	3.564595	3.083789	3.237066	3.211334	2.744449	2.906065	3.177623	2.233504	3.738820	2.557507	3.239049	3.529777	2.465234	3.451955	2.641871	3.167258	3.078964	2.549861	3.636829	3.118628	4.505401	3.829561	4.033649	3.882229	2.853211	3.448258	3.424081	2.839227	3.336260	3.607434	3.117636	2.732796	2.893373	2.672652	2.580012	2.170555	3.232055	3.631068	3.039850	3.896692	4.454177	2.852541	3.045010	3.228092	3.727777	3.337240	2.853881	4.711061	5.352353	3.533861	4.440429	3.965051	3.999939	2.267875	2.468347	2.704150	3.197556	2.891760	3.487379	2.903578	2.513750	2.566909	2.999696	2.731508	3.003504	2.214844	3.113709	2.331022	2.995855	2.808751	3.966381	3.979303	3.725912	2.838723	3.315508	2.820464	2.953566	3.017576	3.650366	2.605305	2.445604	2.926805	3.200905	2.896692	3.721093	2.849726	3.541417	3.164739	2.833275	2.776120	2.339253	3.116143	2.819873	4.210891	2.381657	2.462997	2.885305	2.948560	2.468495	3.612953	3.911216	4.084337	3.414372	3.528981	4.500316	2.168203	3.329967	3.025347	3.140697	3.910090	4.658601	2.781396	2.615108	5.068082	3.934655	3.799458	2.753813	3.018451	3.046807	3.029546	3.649783	3.153479	2.472171	2.259594	3.360385	3.086609	3.452752	4.629357	2.488410	3.028978	3.068557	2.477121	2.633064	3.066624	4.264485	2.494294	2.543820	3.606714	3.923441	3.595198	2.406029	2.869114	4.643145	2.630835	3.718294	2.920489	3.460372	3.194098	4.967117	2.549861	3.258374	3.179121	3.165778	4.244161	3.552729	2.874598	3.666031	2.863680	2.791059	2.645815	4.361326	3.019116	3.752148	3.345805	2.066326	2.281261	3.224533	2.928293	3.732185	3.317478	2.557146	1.995635	3.265549	3.749651	4.282157	4.935629	5.021235	2.566438	4.801784	4.146723	3.539841	4.127254	2.803457	3.309098	3.707229	2.555094	4.022989	2.687796	4.29389	2.918764	2.834166	2.620448	3.121691	4.432912	2.443420	4.851275	2.360783	2.597805	3.971749	3.863579	2.869642	3.313783	3.447778	2.437275	2.900531	4.314379	3.215558	2.870872	2.159266	2.508530	3.690223	4.030515	4.141152	3.265855	2.915189	3.145103	2.689398	2.913867	2.838786	3.217905	2.750200	3.034548	3.923487	2.656577	3.255972	3.091561	3.926224	4.732555	2.957703	3.326356	3.081347	3.364101	3.543484	3.609007	4.292916	3.090681	4.471723	3.938970	3.476846	3.040919	2.267406	4.260586	4.178102	2.692671	4.007261	3.050534	4.534979	3.371326	2.926342	2.516800	2.335859	2.854670	3.563576	3.863828	2.690196	2.702775	3.354780	2.971879	3.706163	3.096319	3.020693	4.341318	2.835183	3.490647	4.216324	2.740442	3.492956	2.930440	3.042575	2.957703	2.703205	4.006235	3.023335	2.207095	3.216562	3.847881	4.581079	4.156458	3.383690	4.486317	2.845408	3.431942	2.322219	2.954484	3.867243	3.255128	3.036868	2.896747	4.299568	2.305566	3.753721	2.915347	2.709440	2.285332	3.241073	2.800373	3.528698	3.61515	3.175367	4.428803	2.617839	4.478188	4.836065	2.609167	3.896162	3.333830	3.498352	3.829715	2.960281	3.456897	2.601625	2.455606	2.332236	4.941254	2.604442	3.291702	3.340801	2.660486	3.446413	4.434666	3.699031	3.478249	2.971832	3.939350	4.862610	4.180613	2.959375	2.893484	3.631677	2.711976	2.495128	2.275772	3.729149	2.871047	4.028592	4.547978	4.439475	3.263731	4.357849	3.446428	3.243237	3.098921	3.909283	3.313825	2.938920	2.364739	3.768771	3.672670	3.550937	2.781325	2.825361	3.077077	2.562412	2.718834	3.136847	2.444201	2.856064	3.364082	2.996293	2.406370	3.183555	3.579521	4.006907	3.479446	4.382887	4.694308	3.371234	3.966085	4.760098	2.950949	3.374455	2.572988	2.508530	3.374638	2.927114	3.177883	2.883661	3.041116	4.401597	3.341949	3.564346	2.571010	2.880356	3.327604	2.982723	3.000434	2.453624	2.583539	3.440106	2.870989	4.565019	3.61272	4.436455	3.486175	2.564429	4.221589	3.647324	3.271818	3.708191	4.132804	3.542912	2.294466	3.258182	3.567626	4.013650	2.807332	3.447173	3.755112	3.592521	3.710211	4.356315	4.08508	2.006038	3.581802	3.155761	3.114044	4.311050	3.570263	2.264582	3.052078	4.149933	3.746595	3.748328	2.649919	3.558457	3.575142	3.477367	4.451323	4.096382	3.100164	3.193903	3.141983	2.622214	4.285746	3.768231	4.096128	4.361992	2.769451	3.264534	3.359399	2.276462	2.829239	3.405039	5.008653	3.960066	2.453930	2.656481	3.689531	3.287555	3.892968	3.244005	2.867114	4.102348	2.533772	4.047041	4.155278	2.879096	3.642583	3.186391	2.259116	2.685383	2.728516	3.131234	2.546049	4.282808	3.951774	3.126586	4.229869	3.505991	2.955976	3.206313	4.026835	4.588745	2.911104	4.457743	3.289767	2.402433	3.166223	2.386142	3.814946	2.745933	2.608312	4.574163	3.319730	3.920217	1.845718	2.603469	3.134273	3.597179	2.712060	2.644340	3.058236	4.024986	2.945222	2.809492	2.706376	2.752509	3.362162	2.278982	2.984797	2.362105	4.785282	3.907320	4.085879	3.525524	3.004665	3.766903	2.988826	3.289745	2.660391	3.634518	3.290747	2.560385	3.185174	2.760272	2.626853	3.180986	4.143517	2.492481	2.872972	2.259594	3.327829	3.345942	3.499701	3.937262	3.516628	4.422197	3.906965	2.644143	2.689753	2.972249	3.574714	3.759358	3.290880	3.424784	2.592399	3.988791	4.077829	3.205204	3.746385	3.814161	2.827821	3.857405	3.438067	2.439491	3.888045	2.782974	2.494294	2.544192	3.908790	2.459242	4.356254	4.330959	2.89867	3.882308	4.046171	3.117039	4.069383
PDAG965NUZ	1	27	28	PD	BL	76.3	2	Male	3.107447	3.244623	3.257871	4.028018	2.138934	2.742804	2.661245	2.950121	3.539176	2.906281	4.115384	2.646991	2.233250	2.700098	3.743322	4.421191	3.873605	2.672929	3.522679	4.153757	3.689611	4.275760	4.250271	3.128238	3.580914	3.564678	2.226342	2.632255	4.088699	4.642884	4.448134	2.253822	3.461529	2.964495	2.074085	2.870930	4.301919	3.745403	2.615108	3.627642	3.959194	3.742851	4.175460	5.124240	4.220587	4.083058	3.691285	4.619448	5.412079	3.626422	3.360139	2.933588	3.555421	3.542850	2.934195	3.206502	2.708166	4.939658	3.170643	3.484043	3.974314	3.084719	3.624138	2.60206	3.441915	2.586362	2.872448	3.057324	2.489255	2.270912	2.908163	2.754195	3.232183	3.022799	3.010427	3.269746	3.134528	4.079601	3.255851	3.198272	3.297848	3.995745	3.174060	3.195401	3.056600	4.623084	3.385124	3.361369	3.473735	2.960756	2.703635	2.709015	2.962653	2.506505	2.776483	3.097708	3.595210	2.890141	3.563113	3.281056	4.029591	4.281095	4.118003	3.558589	3.430945	2.903036	3.907589	3.915131	3.848528	2.693903	3.264676	3.514335	4.914363	3.243137	4.045745	4.823241	3.417887	3.587442	4.796785	3.634437	3.317938	3.718377	4.231419	2.724849	2.946550	3.673638	3.059488	4.121750	2.375846	3.243137	3.294643	2.503382	2.814580	3.79563	3.612487	2.570076	4.334844	4.213696	2.625827	4.065587	3.290168	3.022305	3.055531	3.029871	3.107549	3.760762	3.221284	3.736898	3.698796	2.980594	2.954532	3.275219	3.305201	3.970147	3.143702	2.848559	3.452078	2.451172	3.262024	2.817235	2.882354	3.008600	3.105783	3.326929	3.775982	3.543820	3.438874	2.583085	4.175526	2.429914	2.374748	4.729247	2.851503	2.529302	2.722058	4.154512	2.758230	4.483590	2.257439	2.678973	3.642880	3.915088	2.342225	3.919225	3.077876	2.741309	3.795943	3.643008	2.541579	3.347642	3.192874	4.099570	3.873838	3.617231	3.161518	2.849296	2.508395	3.656778	2.825880	2.736556	3.560301	3.611936	3.332560	4.030158	4.300532	3.121396	3.085825	4.212105	2.879726	3.132804	4.715550	3.304857	2.067071	4.070396	2.972203	3.388918	4.088459	3.98200	2.915347	3.118430	3.399154	4.393017	4.275675	4.205226	2.992554	3.677698	3.632822	3.391641	2.757548	3.840495	3.575257	2.906119	2.570309	3.933184	4.589664	3.890583	3.209327	3.344196	3.526494	2.878292	2.503109	3.874296	3.641920	4.794521	2.485580	2.533263	2.742175	3.591309	3.128076	4.384705	3.173536	3.297323	2.838093	2.236033	3.128722	4.67242	3.934685	2.723045	3.574610	2.824841	3.161996	3.152625	4.710611	4.287889	3.681440	3.603437	3.994344	2.960614	3.603772	2.139564	2.899054	2.590396	4.268814	3.231699	3.221649	3.472522	2.966470	2.992421	3.453853	2.582631	2.888685	4.396806	2.635484	2.474944	2.221153	4.609417	3.679210	3.583754	3.510277	4.077793	2.949000	4.397676	4.627936	2.502017	3.392873	2.689930	2.351603	3.123198	2.451326	3.361388	3.047002	2.564074	3.894720	3.662890	2.368844	2.325516	3.541217	2.431203	3.706590	2.574263	2.418135	2.668759	2.649627	3.505069	3.338934	2.386677	2.959089	3.075182	3.855876	3.056905	3.699933	2.663889	4.925982	3.453318	2.885191	2.934549	3.793595	2.772395	4.081693	4.406629	2.978409	2.675870	2.701309	4.290909	2.830653	2.718419	5.083698	2.678791	3.071514	3.814261	2.773055	3.428588	3.023746	3.545851	2.977815	3.710033	2.856910	2.491782	2.876622	3.649646	3.346196	3.773574	3.023664	2.470410	3.444154	3.477541	3.816778	3.245044	2.201397	2.867055	3.247065	3.704005	4.217894	3.143296	3.342778	2.312600	2.380392	4.374937	3.937513	3.030883	2.851992	4.375397	2.540329	3.370402	3.881738	4.565699	2.569959	3.806899	4.36128	2.773347	2.812646	3.376194	2.854670	2.997561	3.564595	3.083789	3.237066	3.211334	2.744449	2.906065	3.177623	2.233504	3.738820	2.557507	3.239049	3.529777	2.465234	3.451955	2.641871	3.167258	3.078964	2.549861	3.636829	3.118628	4.505401	3.829561	4.033649	3.882229	2.853211	3.448258	3.424081	2.839227	3.336260	3.607434	3.117636	2.732796	2.893373	2.672652	2.580012	2.170555	3.232055	3.631068	3.039850	3.896692	4.454177	2.852541	3.045010	3.228092	3.727777	3.337240	2.853881	4.711061	5.352353	3.533861	4.440429	3.965051	3.999939	2.267875	2.468347	2.704150	3.197556	2.891760	3.487379	2.903578	2.513750	2.566909	2.999696	2.731508	3.003504	2.214844	3.113709	2.331022	2.995855	2.808751	3.966381	3.979303	3.725912	2.838723	3.315508	2.820464	2.953566	3.017576	3.650366	2.605305	2.445604	2.926805	3.200905	2.896692	3.721093	2.849726	3.541417	3.164739	2.833275	2.776120	2.339253	3.116143	2.819873	4.210891	2.381657	2.462997	2.885305	2.948560	2.468495	3.612953	3.911216	4.084337	3.414372	3.528981	4.500316	2.168203	3.329967	3.025347	3.140697	3.910090	4.658601	2.781396	2.615108	5.068082	3.934655	3.799458	2.753813	3.018451	3.046807	3.029546	3.649783	3.153479	2.472171	2.259594	3.360385	3.086609	3.452752	4.629357	2.488410	3.028978	3.068557	2.477121	2.633064	3.066624	4.264485	2.494294	2.543820	3.606714	3.923441	3.595198	2.406029	2.869114	4.643145	2.630835	3.718294	2.920489	3.460372	3.194098	4.967117	2.549861	3.258374	3.179121	3.165778	4.244161	3.552729	2.874598	3.666031	2.863680	2.791059	2.645815	4.361326	3.019116	3.752148	3.345805	2.066326	2.281261	3.224533	2.928293	3.732185	3.317478	2.557146	1.995635	3.265549	3.749651	4.282157	4.935629	5.021235	2.566438	4.801784	4.146723	3.539841	4.127254	2.803457	3.309098	3.707229	2.555094	4.022989	2.687796	4.29389	2.918764	2.834166	2.620448	3.121691	4.432912	2.443420	4.851275	2.360783	2.597805	3.971749	3.863579	2.869642	3.313783	3.447778	2.437275	2.900531	4.314379	3.215558	2.870872	2.159266	2.508530	3.690223	4.030515	4.141152	3.265855	2.915189	3.145103	2.689398	2.913867	2.838786	3.217905	2.750200	3.034548	3.923487	2.656577	3.255972	3.091561	3.926224	4.732555	2.957703	3.326356	3.081347	3.364101	3.543484	3.609007	4.292916	3.090681	4.471723	3.938970	3.476846	3.040919	2.267406	4.260586	4.178102	2.692671	4.007261	3.050534	4.534979	3.371326	2.926342	2.516800	2.335859	2.854670	3.563576	3.863828	2.690196	2.702775	3.354780	2.971879	3.706163	3.096319	3.020693	4.341318	2.835183	3.490647	4.216324	2.740442	3.492956	2.930440	3.042575	2.957703	2.703205	4.006235	3.023335	2.207095	3.216562	3.847881	4.581079	4.156458	3.383690	4.486317	2.845408	3.431942	2.322219	2.954484	3.867243	3.255128	3.036868	2.896747	4.299568	2.305566	3.753721	2.915347	2.709440	2.285332	3.241073	2.800373	3.528698	3.61515	3.175367	4.428803	2.617839	4.478188	4.836065	2.609167	3.896162	3.333830	3.498352	3.829715	2.960281	3.456897	2.601625	2.455606	2.332236	4.941254	2.604442	3.291702	3.340801	2.660486	3.446413	4.434666	3.699031	3.478249	2.971832	3.939350	4.862610	4.180613	2.959375	2.893484	3.631677	2.711976	2.495128	2.275772	3.729149	2.871047	4.028592	4.547978	4.439475	3.263731	4.357849	3.446428	3.243237	3.098921	3.909283	3.313825	2.938920	2.364739	3.768771	3.672670	3.550937	2.781325	2.825361	3.077077	2.562412	2.718834	3.136847	2.444201	2.856064	3.364082	2.996293	2.406370	3.183555	3.579521	4.006907	3.479446	4.382887	4.694308	3.371234	3.966085	4.760098	2.950949	3.374455	2.572988	2.508530	3.374638	2.927114	3.177883	2.883661	3.041116	4.401597	3.341949	3.564346	2.571010	2.880356	3.327604	2.982723	3.000434	2.453624	2.583539	3.440106	2.870989	4.565019	3.61272	4.436455	3.486175	2.564429	4.221589	3.647324	3.271818	3.708191	4.132804	3.542912	2.294466	3.258182	3.567626	4.013650	2.807332	3.447173	3.755112	3.592521	3.710211	4.356315	4.08508	2.006038	3.581802	3.155761	3.114044	4.311050	3.570263	2.264582	3.052078	4.149933	3.746595	3.748328	2.649919	3.558457	3.575142	3.477367	4.451323	4.096382	3.100164	3.193903	3.141983	2.622214	4.285746	3.768231	4.096128	4.361992	2.769451	3.264534	3.359399	2.276462	2.829239	3.405039	5.008653	3.960066	2.453930	2.656481	3.689531	3.287555	3.892968	3.244005	2.867114	4.102348	2.533772	4.047041	4.155278	2.879096	3.642583	3.186391	2.259116	2.685383	2.728516	3.131234	2.546049	4.282808	3.951774	3.126586	4.229869	3.505991	2.955976	3.206313	4.026835	4.588745	2.911104	4.457743	3.289767	2.402433	3.166223	2.386142	3.814946	2.745933	2.608312	4.574163	3.319730	3.920217	1.845718	2.603469	3.134273	3.597179	2.712060	2.644340	3.058236	4.024986	2.945222	2.809492	2.706376	2.752509	3.362162	2.278982	2.984797	2.362105	4.785282	3.907320	4.085879	3.525524	3.004665	3.766903	2.988826	3.289745	2.660391	3.634518	3.290747	2.560385	3.185174	2.760272	2.626853	3.180986	4.143517	2.492481	2.872972	2.259594	3.327829	3.345942	3.499701	3.937262	3.516628	4.422197	3.906965	2.644143	2.689753	2.972249	3.574714	3.759358	3.290880	3.424784	2.592399	3.988791	4.077829	3.205204	3.746385	3.814161	2.827821	3.857405	3.438067	2.439491	3.888045	2.782974	2.494294	2.544192	3.908790	2.459242	4.356254	4.330959	2.89867	3.882308	4.046171	3.117039	4.069383
PDAG965NUZ	2	25	28	PD	BL	76.3	2	Male	3.107447	3.244623	3.257871	4.028018	2.138934	2.742804	2.661245	2.950121	3.539176	2.906281	4.115384	2.646991	2.233250	2.700098	3.743322	4.421191	3.873605	2.672929	3.522679	4.153757	3.689611	4.275760	4.250271	3.128238	3.580914	3.564678	2.226342	2.632255	4.088699	4.642884	4.448134	2.253822	3.461529	2.964495	2.074085	2.870930	4.301919	3.745403	2.615108	3.627642	3.959194	3.742851	4.175460	5.124240	4.220587	4.083058	3.691285	4.619448	5.412079	3.626422	3.360139	2.933588	3.555421	3.542850	2.934195	3.206502	2.708166	4.939658	3.170643	3.484043	3.974314	3.084719	3.624138	2.60206	3.441915	2.586362	2.872448	3.057324	2.489255	2.270912	2.908163	2.754195	3.232183	3.022799	3.010427	3.269746	3.134528	4.079601	3.255851	3.198272	3.297848	3.995745	3.174060	3.195401	3.056600	4.623084	3.385124	3.361369	3.473735	2.960756	2.703635	2.709015	2.962653	2.506505	2.776483	3.097708	3.595210	2.890141	3.563113	3.281056	4.029591	4.281095	4.118003	3.558589	3.430945	2.903036	3.907589	3.915131	3.848528	2.693903	3.264676	3.514335	4.914363	3.243137	4.045745	4.823241	3.417887	3.587442	4.796785	3.634437	3.317938	3.718377	4.231419	2.724849	2.946550	3.673638	3.059488	4.121750	2.375846	3.243137	3.294643	2.503382	2.814580	3.79563	3.612487	2.570076	4.334844	4.213696	2.625827	4.065587	3.290168	3.022305	3.055531	3.029871	3.107549	3.760762	3.221284	3.736898	3.698796	2.980594	2.954532	3.275219	3.305201	3.970147	3.143702	2.848559	3.452078	2.451172	3.262024	2.817235	2.882354	3.008600	3.105783	3.326929	3.775982	3.543820	3.438874	2.583085	4.175526	2.429914	2.374748	4.729247	2.851503	2.529302	2.722058	4.154512	2.758230	4.483590	2.257439	2.678973	3.642880	3.915088	2.342225	3.919225	3.077876	2.741309	3.795943	3.643008	2.541579	3.347642	3.192874	4.099570	3.873838	3.617231	3.161518	2.849296	2.508395	3.656778	2.825880	2.736556	3.560301	3.611936	3.332560	4.030158	4.300532	3.121396	3.085825	4.212105	2.879726	3.132804	4.715550	3.304857	2.067071	4.070396	2.972203	3.388918	4.088459	3.98200	2.915347	3.118430	3.399154	4.393017	4.275675	4.205226	2.992554	3.677698	3.632822	3.391641	2.757548	3.840495	3.575257	2.906119	2.570309	3.933184	4.589664	3.890583	3.209327	3.344196	3.526494	2.878292	2.503109	3.874296	3.641920	4.794521	2.485580	2.533263	2.742175	3.591309	3.128076	4.384705	3.173536	3.297323	2.838093	2.236033	3.128722	4.67242	3.934685	2.723045	3.574610	2.824841	3.161996	3.152625	4.710611	4.287889	3.681440	3.603437	3.994344	2.960614	3.603772	2.139564	2.899054	2.590396	4.268814	3.231699	3.221649	3.472522	2.966470	2.992421	3.453853	2.582631	2.888685	4.396806	2.635484	2.474944	2.221153	4.609417	3.679210	3.583754	3.510277	4.077793	2.949000	4.397676	4.627936	2.502017	3.392873	2.689930	2.351603	3.123198	2.451326	3.361388	3.047002	2.564074	3.894720	3.662890	2.368844	2.325516	3.541217	2.431203	3.706590	2.574263	2.418135	2.668759	2.649627	3.505069	3.338934	2.386677	2.959089	3.075182	3.855876	3.056905	3.699933	2.663889	4.925982	3.453318	2.885191	2.934549	3.793595	2.772395	4.081693	4.406629	2.978409	2.675870	2.701309	4.290909	2.830653	2.718419	5.083698	2.678791	3.071514	3.814261	2.773055	3.428588	3.023746	3.545851	2.977815	3.710033	2.856910	2.491782	2.876622	3.649646	3.346196	3.773574	3.023664	2.470410	3.444154	3.477541	3.816778	3.245044	2.201397	2.867055	3.247065	3.704005	4.217894	3.143296	3.342778	2.312600	2.380392	4.374937	3.937513	3.030883	2.851992	4.375397	2.540329	3.370402	3.881738	4.565699	2.569959	3.806899	4.36128	2.773347	2.812646	3.376194	2.854670	2.997561	3.564595	3.083789	3.237066	3.211334	2.744449	2.906065	3.177623	2.233504	3.738820	2.557507	3.239049	3.529777	2.465234	3.451955	2.641871	3.167258	3.078964	2.549861	3.636829	3.118628	4.505401	3.829561	4.033649	3.882229	2.853211	3.448258	3.424081	2.839227	3.336260	3.607434	3.117636	2.732796	2.893373	2.672652	2.580012	2.170555	3.232055	3.631068	3.039850	3.896692	4.454177	2.852541	3.045010	3.228092	3.727777	3.337240	2.853881	4.711061	5.352353	3.533861	4.440429	3.965051	3.999939	2.267875	2.468347	2.704150	3.197556	2.891760	3.487379	2.903578	2.513750	2.566909	2.999696	2.731508	3.003504	2.214844	3.113709	2.331022	2.995855	2.808751	3.966381	3.979303	3.725912	2.838723	3.315508	2.820464	2.953566	3.017576	3.650366	2.605305	2.445604	2.926805	3.200905	2.896692	3.721093	2.849726	3.541417	3.164739	2.833275	2.776120	2.339253	3.116143	2.819873	4.210891	2.381657	2.462997	2.885305	2.948560	2.468495	3.612953	3.911216	4.084337	3.414372	3.528981	4.500316	2.168203	3.329967	3.025347	3.140697	3.910090	4.658601	2.781396	2.615108	5.068082	3.934655	3.799458	2.753813	3.018451	3.046807	3.029546	3.649783	3.153479	2.472171	2.259594	3.360385	3.086609	3.452752	4.629357	2.488410	3.028978	3.068557	2.477121	2.633064	3.066624	4.264485	2.494294	2.543820	3.606714	3.923441	3.595198	2.406029	2.869114	4.643145	2.630835	3.718294	2.920489	3.460372	3.194098	4.967117	2.549861	3.258374	3.179121	3.165778	4.244161	3.552729	2.874598	3.666031	2.863680	2.791059	2.645815	4.361326	3.019116	3.752148	3.345805	2.066326	2.281261	3.224533	2.928293	3.732185	3.317478	2.557146	1.995635	3.265549	3.749651	4.282157	4.935629	5.021235	2.566438	4.801784	4.146723	3.539841	4.127254	2.803457	3.309098	3.707229	2.555094	4.022989	2.687796	4.29389	2.918764	2.834166	2.620448	3.121691	4.432912	2.443420	4.851275	2.360783	2.597805	3.971749	3.863579	2.869642	3.313783	3.447778	2.437275	2.900531	4.314379	3.215558	2.870872	2.159266	2.508530	3.690223	4.030515	4.141152	3.265855	2.915189	3.145103	2.689398	2.913867	2.838786	3.217905	2.750200	3.034548	3.923487	2.656577	3.255972	3.091561	3.926224	4.732555	2.957703	3.326356	3.081347	3.364101	3.543484	3.609007	4.292916	3.090681	4.471723	3.938970	3.476846	3.040919	2.267406	4.260586	4.178102	2.692671	4.007261	3.050534	4.534979	3.371326	2.926342	2.516800	2.335859	2.854670	3.563576	3.863828	2.690196	2.702775	3.354780	2.971879	3.706163	3.096319	3.020693	4.341318	2.835183	3.490647	4.216324	2.740442	3.492956	2.930440	3.042575	2.957703	2.703205	4.006235	3.023335	2.207095	3.216562	3.847881	4.581079	4.156458	3.383690	4.486317	2.845408	3.431942	2.322219	2.954484	3.867243	3.255128	3.036868	2.896747	4.299568	2.305566	3.753721	2.915347	2.709440	2.285332	3.241073	2.800373	3.528698	3.61515	3.175367	4.428803	2.617839	4.478188	4.836065	2.609167	3.896162	3.333830	3.498352	3.829715	2.960281	3.456897	2.601625	2.455606	2.332236	4.941254	2.604442	3.291702	3.340801	2.660486	3.446413	4.434666	3.699031	3.478249	2.971832	3.939350	4.862610	4.180613	2.959375	2.893484	3.631677	2.711976	2.495128	2.275772	3.729149	2.871047	4.028592	4.547978	4.439475	3.263731	4.357849	3.446428	3.243237	3.098921	3.909283	3.313825	2.938920	2.364739	3.768771	3.672670	3.550937	2.781325	2.825361	3.077077	2.562412	2.718834	3.136847	2.444201	2.856064	3.364082	2.996293	2.406370	3.183555	3.579521	4.006907	3.479446	4.382887	4.694308	3.371234	3.966085	4.760098	2.950949	3.374455	2.572988	2.508530	3.374638	2.927114	3.177883	2.883661	3.041116	4.401597	3.341949	3.564346	2.571010	2.880356	3.327604	2.982723	3.000434	2.453624	2.583539	3.440106	2.870989	4.565019	3.61272	4.436455	3.486175	2.564429	4.221589	3.647324	3.271818	3.708191	4.132804	3.542912	2.294466	3.258182	3.567626	4.013650	2.807332	3.447173	3.755112	3.592521	3.710211	4.356315	4.08508	2.006038	3.581802	3.155761	3.114044	4.311050	3.570263	2.264582	3.052078	4.149933	3.746595	3.748328	2.649919	3.558457	3.575142	3.477367	4.451323	4.096382	3.100164	3.193903	3.141983	2.622214	4.285746	3.768231	4.096128	4.361992	2.769451	3.264534	3.359399	2.276462	2.829239	3.405039	5.008653	3.960066	2.453930	2.656481	3.689531	3.287555	3.892968	3.244005	2.867114	4.102348	2.533772	4.047041	4.155278	2.879096	3.642583	3.186391	2.259116	2.685383	2.728516	3.131234	2.546049	4.282808	3.951774	3.126586	4.229869	3.505991	2.955976	3.206313	4.026835	4.588745	2.911104	4.457743	3.289767	2.402433	3.166223	2.386142	3.814946	2.745933	2.608312	4.574163	3.319730	3.920217	1.845718	2.603469	3.134273	3.597179	2.712060	2.644340	3.058236	4.024986	2.945222	2.809492	2.706376	2.752509	3.362162	2.278982	2.984797	2.362105	4.785282	3.907320	4.085879	3.525524	3.004665	3.766903	2.988826	3.289745	2.660391	3.634518	3.290747	2.560385	3.185174	2.760272	2.626853	3.180986	4.143517	2.492481	2.872972	2.259594	3.327829	3.345942	3.499701	3.937262	3.516628	4.422197	3.906965	2.644143	2.689753	2.972249	3.574714	3.759358	3.290880	3.424784	2.592399	3.988791	4.077829	3.205204	3.746385	3.814161	2.827821	3.857405	3.438067	2.439491	3.888045	2.782974	2.494294	2.544192	3.908790	2.459242	4.356254	4.330959	2.89867	3.882308	4.046171	3.117039	4.069383
PDAL120HLU	0	29	29	PD	BL	64.5	13	Female	2.949926	3.300943	3.388492	4.062589	2.023252	2.641672	2.552790	2.776919	3.782637	2.903416	3.165066	2.533263	2.135769	2.585686	3.839195	4.611272	3.709041	2.710710	3.383995	3.902596	3.680979	3.942276	4.224657	3.029018	3.508637	3.515582	2.344196	2.415474	4.011211	4.588042	4.377071	2.228400	3.627233	2.864630	2.275542	2.631748	4.212643	3.655110	2.480151	3.542240	3.845514	4.130459	4.008042	5.116426	4.192827	3.804085	3.554089	4.442785	5.316172	3.540455	2.971183	2.794488	3.534102	3.389503	4.422069	3.340385	2.638090	5.026072	2.983807	3.784967	3.764154	3.109848	3.351352	2.47261	3.485764	2.487280	2.762529	2.838912	2.342620	2.188366	2.859138	2.632052	3.328094	2.998346	2.955784	3.200467	3.546777	4.112256	3.268461	3.072103	3.158061	3.839685	2.965578	3.326561	2.903633	4.464738	3.558864	3.293164	3.318126	2.692759	2.586587	2.517064	2.876276	2.413300	2.643847	3.271795	3.630845	2.473633	3.802240	3.233047	4.180241	4.204362	3.863977	3.546814	3.480237	2.812713	3.785501	3.940696	3.816056	2.764624	3.233453	3.409493	4.896532	3.095100	4.183384	4.733404	3.270213	3.520248	4.704499	3.702715	3.258637	3.632397	4.190304	2.522183	3.148232	3.854695	3.661178	3.804671	2.206826	3.283799	3.306425	2.455910	2.756712	3.80388	3.541991	2.487421	4.473008	3.776774	2.537063	3.803887	3.246548	2.785757	3.032377	2.820530	3.054077	3.632548	3.261382	3.855295	3.796429	2.829239	2.871047	3.405893	3.389326	3.983261	2.498862	2.712986	3.166045	2.265054	3.185316	2.629410	2.761251	2.442793	3.013890	3.196342	3.858910	3.443091	3.216271	2.121888	4.146103	2.385785	2.209247	4.798121	2.712397	2.507586	2.595717	3.996117	2.758533	4.238914	2.175512	2.546543	3.706812	3.764393	2.213252	3.950866	3.082283	2.894372	4.010758	3.850168	2.712650	3.716846	3.106055	4.061833	3.672467	3.580012	2.970114	2.589167	2.483730	3.589078	2.693551	2.579326	3.682461	3.463744	2.614581	4.162549	4.094174	2.766190	3.058350	4.118784	3.303390	3.028449	4.433631	3.220291	2.053846	4.188172	2.490801	3.468362	3.793776	3.68946	2.762604	3.127558	3.443185	4.249184	4.433808	4.244455	3.127267	3.506857	3.516958	3.288227	2.744606	3.760882	3.728768	2.766413	2.520090	3.820044	4.505976	3.726099	2.462548	3.268438	3.643275	2.698622	2.373280	3.942087	3.572325	4.690978	2.373464	2.397766	2.868938	3.595584	3.064982	4.314621	3.265761	2.997343	2.790426	2.225309	3.145538	4.66639	3.773465	2.430720	3.349239	2.879612	3.147120	3.269910	4.788306	4.184796	3.789856	3.558493	4.147358	2.935558	4.043716	2.064083	2.799065	2.405688	4.339938	3.203604	3.285850	3.621944	2.853272	2.916822	3.602114	2.485438	2.719165	4.363294	2.513617	2.493737	2.121888	4.652776	3.613408	3.435669	3.489241	4.552880	2.796088	4.369268	4.584553	2.429591	3.467312	2.662002	2.476107	3.360726	2.356026	3.516284	3.076822	2.522314	3.748025	3.818219	2.248709	2.310906	3.422754	2.378034	4.287385	2.467904	2.266702	2.517592	2.539452	2.604010	3.315088	2.655235	2.830717	2.784546	2.938970	2.948560	3.524734	2.484442	4.689599	3.485395	3.948066	2.825556	3.920645	2.803662	3.696339	4.283369	2.804548	2.478711	2.561698	4.347240	2.723948	2.642761	5.003971	2.593729	3.133986	3.033906	2.480294	3.519776	3.008643	2.611405	3.108159	3.765549	2.999522	2.393400	2.810300	3.816997	3.045049	3.789341	2.860038	2.482302	3.376796	3.447034	3.885638	3.092896	2.046495	2.792882	2.993392	3.784781	4.054762	3.323108	3.393926	2.210853	2.260787	4.337014	3.346568	2.904012	3.076131	4.306093	2.422097	3.313909	3.909058	4.472597	2.341039	3.765549	4.22366	3.462143	2.332438	3.339869	2.762679	2.933538	3.418566	4.274850	3.553859	3.181472	2.554610	3.018284	3.002900	2.072617	3.751364	2.423246	3.150542	3.491376	2.260071	3.474100	2.555578	3.109106	3.202761	2.558108	3.747241	2.974189	4.454973	3.910758	3.990068	3.749365	2.662380	3.346431	3.404919	2.745777	3.279233	3.664068	3.064233	2.618885	2.928805	2.717671	2.450095	2.145818	3.587172	3.975216	3.130076	3.747326	4.473580	2.678700	3.005438	3.442056	3.727208	3.347701	2.897022	4.725398	5.211216	3.260167	4.490393	3.670496	4.083273	2.179552	2.395326	2.605197	2.772468	2.680879	3.394539	2.875351	2.422426	2.433770	2.909181	2.603794	3.033986	2.087426	2.948413	2.323046	2.405175	2.772468	4.007244	4.045847	3.631373	2.726157	3.265384	2.918607	3.304383	2.903524	3.550130	2.496237	2.382377	2.900367	3.425942	3.218929	3.400158	2.719331	3.064757	3.076058	2.776265	2.604658	2.265054	3.158543	2.572755	4.213125	2.053846	2.477411	2.839918	2.754042	2.296884	3.628348	4.049299	4.224030	3.360915	3.353801	4.370643	2.149527	3.279963	2.982452	3.172194	3.902949	4.526153	2.798029	2.329601	5.058872	4.018163	3.765065	2.573800	3.078783	2.960281	3.173827	3.733823	2.974558	2.357935	2.106191	3.369846	3.006937	3.557339	4.551267	2.377124	2.869290	3.050534	2.361161	2.475671	2.963882	4.329983	2.513617	2.458487	3.512164	3.637300	3.499233	2.552547	2.810165	4.516858	3.081239	3.803989	2.813914	3.436799	3.251784	4.906974	2.444357	3.204011	3.164918	3.110388	4.419653	4.045952	2.982588	3.591610	2.601843	2.483587	2.577951	4.181403	2.868527	3.853047	3.312050	1.980912	2.182700	3.187323	3.486898	3.687288	3.482845	2.447933	2.127105	3.310693	3.727468	4.246811	4.938724	5.000522	2.729651	4.719321	4.028409	3.467386	3.976895	2.617210	3.077513	3.670645	2.452400	4.043504	2.497621	4.50901	2.828596	2.977952	2.499687	2.959041	4.270294	2.294907	4.788094	2.295567	2.440279	3.963826	3.490983	3.024157	3.232310	3.451971	2.583426	2.733358	4.361256	3.070333	2.817896	2.010300	2.471438	3.727915	3.975308	4.030903	3.229835	2.830396	3.003504	2.662380	2.767972	2.739493	3.190892	2.764923	2.866524	3.968422	2.624076	3.128819	3.123067	3.865927	4.574702	2.957272	3.358506	3.389910	3.392063	3.666668	3.432633	4.187377	3.155063	4.242273	3.836033	3.678063	2.963646	2.086004	3.917505	4.143184	2.701136	3.858278	3.084719	4.524066	3.519027	2.844974	2.313445	2.191171	2.788098	3.359437	3.627847	2.551572	2.683497	3.538197	2.824841	3.596256	3.120969	2.827369	4.355664	2.716170	3.321619	4.194495	2.598900	3.498710	2.833019	3.012795	3.037466	2.776992	3.759894	2.911264	2.173186	3.110084	4.187312	4.262563	4.097760	3.388314	4.271904	2.898012	3.312495	2.311330	2.830973	3.764624	2.899875	2.930287	2.708931	4.193219	2.183270	3.876928	2.728273	2.672836	2.139249	3.412931	2.783403	3.555493	3.43870	3.142421	4.453748	2.518251	4.186976	4.623994	2.439648	4.116973	3.197501	3.379759	3.790144	3.060924	3.309524	2.548389	2.181272	2.245266	4.583814	2.580012	3.214500	3.180814	2.593729	4.070987	4.404190	3.647627	3.374602	2.939170	3.873739	4.941339	4.031429	2.938820	2.723948	3.548291	2.676053	2.392345	2.203033	3.619886	2.884739	4.215907	4.556774	4.519747	3.228836	4.299337	3.590452	2.712650	2.958851	3.804930	3.029992	3.038382	2.270912	3.615424	3.635986	2.608526	2.678700	2.751741	2.940417	2.607348	2.642563	3.095588	2.263636	2.784475	3.403258	2.904716	2.210586	3.098609	3.515476	3.811508	3.544998	4.259188	4.558158	3.327686	3.781612	4.628352	2.825751	3.042418	2.483016	2.346939	3.424195	2.968062	2.961136	3.065953	2.802910	4.177069	3.315088	3.491628	2.480007	2.835120	3.195678	2.736715	2.978819	2.286232	2.500374	3.431348	3.426723	4.365286	3.69668	4.419301	3.645717	2.480869	4.266820	3.407238	3.027023	3.727810	4.188740	3.085183	2.238799	3.115677	3.464057	4.108389	2.979321	3.397801	3.759683	3.610245	3.785259	4.368242	3.98772	2.040602	3.517724	3.066289	3.065878	4.373184	3.631525	2.321598	3.020900	2.376212	3.639606	3.720176	2.549003	4.578858	3.312241	3.387675	4.485271	3.916917	2.996293	3.090505	3.148880	2.438542	4.259637	3.673565	4.182763	4.234960	2.668386	3.203848	3.550827	2.087426	2.716003	2.610554	4.970531	3.975446	2.387034	2.607348	3.656424	3.372857	3.862287	3.265808	2.815179	3.920076	2.356599	4.091192	4.052659	2.943643	3.538373	3.410305	2.112270	2.496930	2.621176	3.038660	2.413467	4.212739	3.907728	3.240549	4.260434	3.521805	2.750586	3.238121	4.128984	4.682631	2.833466	4.550948	3.087107	2.249687	2.868292	2.229170	3.588854	2.595165	2.457730	4.721574	3.396461	4.031384	1.918030	2.686100	3.181929	3.681214	2.586362	2.562293	3.127914	4.075134	3.072434	2.851870	2.566673	2.418467	3.633509	2.214579	2.900804	2.275311	4.642529	3.828118	3.941074	3.346392	3.072911	3.894327	2.891314	3.258996	2.600319	3.891710	3.370717	2.482731	3.170878	2.882752	2.753200	3.113609	4.265370	2.830653	2.897242	2.135133	3.351352	3.224973	3.363029	3.775166	3.372286	4.468290	4.010292	2.521138	2.370698	2.899492	3.585822	3.760671	3.249125	3.509323	2.470704	4.066061	4.080648	3.133411	3.676602	3.695989	2.674494	3.862251	3.645697	2.239049	3.790981	2.627161	2.543944	2.455758	3.720159	2.278067	4.144213	4.368023	2.84398	4.048714	4.193417	3.074451	4.043311
PDAL120HLU	1	26	29	PD	BL	64.5	13	Female	2.949926	3.300943	3.388492	4.062589	2.023252	2.641672	2.552790	2.776919	3.782637	2.903416	3.165066	2.533263	2.135769	2.585686	3.839195	4.611272	3.709041	2.710710	3.383995	3.902596	3.680979	3.942276	4.224657	3.029018	3.508637	3.515582	2.344196	2.415474	4.011211	4.588042	4.377071	2.228400	3.627233	2.864630	2.275542	2.631748	4.212643	3.655110	2.480151	3.542240	3.845514	4.130459	4.008042	5.116426	4.192827	3.804085	3.554089	4.442785	5.316172	3.540455	2.971183	2.794488	3.534102	3.389503	4.422069	3.340385	2.638090	5.026072	2.983807	3.784967	3.764154	3.109848	3.351352	2.47261	3.485764	2.487280	2.762529	2.838912	2.342620	2.188366	2.859138	2.632052	3.328094	2.998346	2.955784	3.200467	3.546777	4.112256	3.268461	3.072103	3.158061	3.839685	2.965578	3.326561	2.903633	4.464738	3.558864	3.293164	3.318126	2.692759	2.586587	2.517064	2.876276	2.413300	2.643847	3.271795	3.630845	2.473633	3.802240	3.233047	4.180241	4.204362	3.863977	3.546814	3.480237	2.812713	3.785501	3.940696	3.816056	2.764624	3.233453	3.409493	4.896532	3.095100	4.183384	4.733404	3.270213	3.520248	4.704499	3.702715	3.258637	3.632397	4.190304	2.522183	3.148232	3.854695	3.661178	3.804671	2.206826	3.283799	3.306425	2.455910	2.756712	3.80388	3.541991	2.487421	4.473008	3.776774	2.537063	3.803887	3.246548	2.785757	3.032377	2.820530	3.054077	3.632548	3.261382	3.855295	3.796429	2.829239	2.871047	3.405893	3.389326	3.983261	2.498862	2.712986	3.166045	2.265054	3.185316	2.629410	2.761251	2.442793	3.013890	3.196342	3.858910	3.443091	3.216271	2.121888	4.146103	2.385785	2.209247	4.798121	2.712397	2.507586	2.595717	3.996117	2.758533	4.238914	2.175512	2.546543	3.706812	3.764393	2.213252	3.950866	3.082283	2.894372	4.010758	3.850168	2.712650	3.716846	3.106055	4.061833	3.672467	3.580012	2.970114	2.589167	2.483730	3.589078	2.693551	2.579326	3.682461	3.463744	2.614581	4.162549	4.094174	2.766190	3.058350	4.118784	3.303390	3.028449	4.433631	3.220291	2.053846	4.188172	2.490801	3.468362	3.793776	3.68946	2.762604	3.127558	3.443185	4.249184	4.433808	4.244455	3.127267	3.506857	3.516958	3.288227	2.744606	3.760882	3.728768	2.766413	2.520090	3.820044	4.505976	3.726099	2.462548	3.268438	3.643275	2.698622	2.373280	3.942087	3.572325	4.690978	2.373464	2.397766	2.868938	3.595584	3.064982	4.314621	3.265761	2.997343	2.790426	2.225309	3.145538	4.66639	3.773465	2.430720	3.349239	2.879612	3.147120	3.269910	4.788306	4.184796	3.789856	3.558493	4.147358	2.935558	4.043716	2.064083	2.799065	2.405688	4.339938	3.203604	3.285850	3.621944	2.853272	2.916822	3.602114	2.485438	2.719165	4.363294	2.513617	2.493737	2.121888	4.652776	3.613408	3.435669	3.489241	4.552880	2.796088	4.369268	4.584553	2.429591	3.467312	2.662002	2.476107	3.360726	2.356026	3.516284	3.076822	2.522314	3.748025	3.818219	2.248709	2.310906	3.422754	2.378034	4.287385	2.467904	2.266702	2.517592	2.539452	2.604010	3.315088	2.655235	2.830717	2.784546	2.938970	2.948560	3.524734	2.484442	4.689599	3.485395	3.948066	2.825556	3.920645	2.803662	3.696339	4.283369	2.804548	2.478711	2.561698	4.347240	2.723948	2.642761	5.003971	2.593729	3.133986	3.033906	2.480294	3.519776	3.008643	2.611405	3.108159	3.765549	2.999522	2.393400	2.810300	3.816997	3.045049	3.789341	2.860038	2.482302	3.376796	3.447034	3.885638	3.092896	2.046495	2.792882	2.993392	3.784781	4.054762	3.323108	3.393926	2.210853	2.260787	4.337014	3.346568	2.904012	3.076131	4.306093	2.422097	3.313909	3.909058	4.472597	2.341039	3.765549	4.22366	3.462143	2.332438	3.339869	2.762679	2.933538	3.418566	4.274850	3.553859	3.181472	2.554610	3.018284	3.002900	2.072617	3.751364	2.423246	3.150542	3.491376	2.260071	3.474100	2.555578	3.109106	3.202761	2.558108	3.747241	2.974189	4.454973	3.910758	3.990068	3.749365	2.662380	3.346431	3.404919	2.745777	3.279233	3.664068	3.064233	2.618885	2.928805	2.717671	2.450095	2.145818	3.587172	3.975216	3.130076	3.747326	4.473580	2.678700	3.005438	3.442056	3.727208	3.347701	2.897022	4.725398	5.211216	3.260167	4.490393	3.670496	4.083273	2.179552	2.395326	2.605197	2.772468	2.680879	3.394539	2.875351	2.422426	2.433770	2.909181	2.603794	3.033986	2.087426	2.948413	2.323046	2.405175	2.772468	4.007244	4.045847	3.631373	2.726157	3.265384	2.918607	3.304383	2.903524	3.550130	2.496237	2.382377	2.900367	3.425942	3.218929	3.400158	2.719331	3.064757	3.076058	2.776265	2.604658	2.265054	3.158543	2.572755	4.213125	2.053846	2.477411	2.839918	2.754042	2.296884	3.628348	4.049299	4.224030	3.360915	3.353801	4.370643	2.149527	3.279963	2.982452	3.172194	3.902949	4.526153	2.798029	2.329601	5.058872	4.018163	3.765065	2.573800	3.078783	2.960281	3.173827	3.733823	2.974558	2.357935	2.106191	3.369846	3.006937	3.557339	4.551267	2.377124	2.869290	3.050534	2.361161	2.475671	2.963882	4.329983	2.513617	2.458487	3.512164	3.637300	3.499233	2.552547	2.810165	4.516858	3.081239	3.803989	2.813914	3.436799	3.251784	4.906974	2.444357	3.204011	3.164918	3.110388	4.419653	4.045952	2.982588	3.591610	2.601843	2.483587	2.577951	4.181403	2.868527	3.853047	3.312050	1.980912	2.182700	3.187323	3.486898	3.687288	3.482845	2.447933	2.127105	3.310693	3.727468	4.246811	4.938724	5.000522	2.729651	4.719321	4.028409	3.467386	3.976895	2.617210	3.077513	3.670645	2.452400	4.043504	2.497621	4.50901	2.828596	2.977952	2.499687	2.959041	4.270294	2.294907	4.788094	2.295567	2.440279	3.963826	3.490983	3.024157	3.232310	3.451971	2.583426	2.733358	4.361256	3.070333	2.817896	2.010300	2.471438	3.727915	3.975308	4.030903	3.229835	2.830396	3.003504	2.662380	2.767972	2.739493	3.190892	2.764923	2.866524	3.968422	2.624076	3.128819	3.123067	3.865927	4.574702	2.957272	3.358506	3.389910	3.392063	3.666668	3.432633	4.187377	3.155063	4.242273	3.836033	3.678063	2.963646	2.086004	3.917505	4.143184	2.701136	3.858278	3.084719	4.524066	3.519027	2.844974	2.313445	2.191171	2.788098	3.359437	3.627847	2.551572	2.683497	3.538197	2.824841	3.596256	3.120969	2.827369	4.355664	2.716170	3.321619	4.194495	2.598900	3.498710	2.833019	3.012795	3.037466	2.776992	3.759894	2.911264	2.173186	3.110084	4.187312	4.262563	4.097760	3.388314	4.271904	2.898012	3.312495	2.311330	2.830973	3.764624	2.899875	2.930287	2.708931	4.193219	2.183270	3.876928	2.728273	2.672836	2.139249	3.412931	2.783403	3.555493	3.43870	3.142421	4.453748	2.518251	4.186976	4.623994	2.439648	4.116973	3.197501	3.379759	3.790144	3.060924	3.309524	2.548389	2.181272	2.245266	4.583814	2.580012	3.214500	3.180814	2.593729	4.070987	4.404190	3.647627	3.374602	2.939170	3.873739	4.941339	4.031429	2.938820	2.723948	3.548291	2.676053	2.392345	2.203033	3.619886	2.884739	4.215907	4.556774	4.519747	3.228836	4.299337	3.590452	2.712650	2.958851	3.804930	3.029992	3.038382	2.270912	3.615424	3.635986	2.608526	2.678700	2.751741	2.940417	2.607348	2.642563	3.095588	2.263636	2.784475	3.403258	2.904716	2.210586	3.098609	3.515476	3.811508	3.544998	4.259188	4.558158	3.327686	3.781612	4.628352	2.825751	3.042418	2.483016	2.346939	3.424195	2.968062	2.961136	3.065953	2.802910	4.177069	3.315088	3.491628	2.480007	2.835120	3.195678	2.736715	2.978819	2.286232	2.500374	3.431348	3.426723	4.365286	3.69668	4.419301	3.645717	2.480869	4.266820	3.407238	3.027023	3.727810	4.188740	3.085183	2.238799	3.115677	3.464057	4.108389	2.979321	3.397801	3.759683	3.610245	3.785259	4.368242	3.98772	2.040602	3.517724	3.066289	3.065878	4.373184	3.631525	2.321598	3.020900	2.376212	3.639606	3.720176	2.549003	4.578858	3.312241	3.387675	4.485271	3.916917	2.996293	3.090505	3.148880	2.438542	4.259637	3.673565	4.182763	4.234960	2.668386	3.203848	3.550827	2.087426	2.716003	2.610554	4.970531	3.975446	2.387034	2.607348	3.656424	3.372857	3.862287	3.265808	2.815179	3.920076	2.356599	4.091192	4.052659	2.943643	3.538373	3.410305	2.112270	2.496930	2.621176	3.038660	2.413467	4.212739	3.907728	3.240549	4.260434	3.521805	2.750586	3.238121	4.128984	4.682631	2.833466	4.550948	3.087107	2.249687	2.868292	2.229170	3.588854	2.595165	2.457730	4.721574	3.396461	4.031384	1.918030	2.686100	3.181929	3.681214	2.586362	2.562293	3.127914	4.075134	3.072434	2.851870	2.566673	2.418467	3.633509	2.214579	2.900804	2.275311	4.642529	3.828118	3.941074	3.346392	3.072911	3.894327	2.891314	3.258996	2.600319	3.891710	3.370717	2.482731	3.170878	2.882752	2.753200	3.113609	4.265370	2.830653	2.897242	2.135133	3.351352	3.224973	3.363029	3.775166	3.372286	4.468290	4.010292	2.521138	2.370698	2.899492	3.585822	3.760671	3.249125	3.509323	2.470704	4.066061	4.080648	3.133411	3.676602	3.695989	2.674494	3.862251	3.645697	2.239049	3.790981	2.627161	2.543944	2.455758	3.720159	2.278067	4.144213	4.368023	2.84398	4.048714	4.193417	3.074451	4.043311

Longitudinal$BSP.Tertile <- with(Longitudinal, factor(
                            findInterval( BSP, c(-Inf,
                               quantile(BSP, probs=c(0.33,0.66)), Inf)), 
                            labels=c("First Tertile","Second Tertile","Third Tertile")))

# Train LME model to see how fasat and slow progressors differ
MoCA1 = lmer(MoCATotal ~ BSP.Tertile*YearstoVisit + AgeAtSample.x + Sex + as.numeric(DiseaseDuration)+ (1 | GUID), data=Longitudinal, REML=F)

data(efc)
theme_set(theme_sjplot())

p5 = plot_model(MoCA1, type = "pred", terms = c("YearstoVisit", "BSP.Tertile"),
           title = " Cognitive Change \n (UTSW + Penn State Cohort)",
           axis.title = c("YearstoVisit","Cognition(MoCA)"),
           axis.labels = NULL, legend.title = "BSP Tertile",
           wrap.title = 50, wrap.labels = 25, axis.lim = NULL, grid.breaks = NULL,
           ci.lvl = 0.9, se = NULL, colors = "Set2", order.terms = c(3,1,2)) + scale_y_continuous(limits = c(20, 30), breaks = c(20,22,24,26,28,30)) + theme_classic() +
  theme(legend.position = c(0.25, 0.2), legend.title = element_text(face = "bold", size = 16), legend.text = element_text(size = 20),
        title = element_text(size = 23),
        axis.title.x = element_text(size = 25, margin = margin(t = 10, r = 0, b = 0, l = 0)),
        axis.title.y = element_text(size = 25, margin = margin(t = 0, r = 12, b = 0, l = 0)),
        axis.text = element_text(size = 25, color = "black"), axis.line = element_line(size = 1), axis.ticks = element_line(size = 1))

p5

Longitudinal$OMD.Tertile <- with(Longitudinal, factor(
                            findInterval( OMD, c(-Inf,
                               quantile(OMD, probs=c(0.33,0.66)), Inf)), 
                            labels=c("First Tertile","Second Tertile","Third Tertile")))

# Train LME model to see how fasat and slow progressors differ
MoCA = lmer(MoCATotal ~ OMD.Tertile*YearstoVisit + AgeAtSample.x + Sex + as.numeric(DiseaseDuration)+ (1 | GUID), data=Longitudinal, REML=F)

data(efc)
theme_set(theme_sjplot())

Longitudinal$FCN1.Tertile <- with(Longitudinal, factor(
                            findInterval( FCN1, c(-Inf,
                               quantile(FCN1, probs=c(0.33,0.66)), Inf)), 
                              labels=c("First Tertile","Second Tertile","Third Tertile")))

# Train LME model to see how fasat and slow progressors differ
MoCA = lmer(MoCATotal ~ FCN1.Tertile*YearstoVisit + AgeAtSample.x + Sex + as.numeric(DiseaseDuration)+ (1 | GUID), data=Longitudinal, REML=F)

data(efc)
theme_set(theme_sjplot())

p5 = plot_model(MoCA, type = "pred", terms = c("YearstoVisit", "FCN1.Tertile"),
           title = " Cognitive Change \n (UTSW + Penn State Cohort)",
           axis.title = c("YearstoVisit","Cognition(MoCA)"),
           axis.labels = NULL, legend.title = "FCN1 Tertile",
           wrap.title = 50, wrap.labels = 25, axis.lim = NULL, grid.breaks = NULL,
           ci.lvl = 0.9, se = NULL, colors = "Set2", order.terms = c(3,1,2)) + scale_y_continuous(limits = c(20, 30), breaks = c(20,22,24,26,28,30)) + theme_classic() +
  theme(legend.position = c(0.25, 0.2), legend.title = element_text(face = "bold", size = 16), legend.text = element_text(size = 20),
        title = element_text(size = 23),
        axis.title.x = element_text(size = 25, margin = margin(t = 10, r = 0, b = 0, l = 0)),
        axis.title.y = element_text(size = 25, margin = margin(t = 0, r = 12, b = 0, l = 0)),
        axis.text = element_text(size = 25, color = "black"), axis.line = element_line(size = 1), axis.ticks = element_line(size = 1))

p5

Longitudinal$CRP.Tertile <- with(Longitudinal, factor(
                            findInterval( CRP, c(-Inf,
                               quantile(CRP, probs=c(0.33,0.66)), Inf)), 
                            labels=c("First Quartile","Second Quartile","Third Quartile")))


# Train LME model to see how fasat and slow progressors differ
MoCA = lmer(MoCATotal ~ CRP.Tertile*YearstoVisit + AgeAtSample.x + Sex + as.numeric(DiseaseDuration)+ (1 | GUID), data=Longitudinal, REML=F)

data(efc)
theme_set(theme_sjplot())

p5 = plot_model(MoCA, type = "pred", terms = c("YearstoVisit", "CRP.Tertile"),
           title = " Cognitive Change \n (UTSW + Penn State Cohort)",
           axis.title = c("YearstoVisit","Cognition(MoCA)"),
           axis.labels = NULL, legend.title = "CRP Tertile",
           wrap.title = 50, wrap.labels = 25, axis.lim = NULL, grid.breaks = NULL,
           ci.lvl = 0.9, se = NULL, colors = "Set2", order.terms = c(3,1,2)) + scale_y_continuous(limits = c(20, 30), breaks = c(20,22,24,26,28,30)) + theme_classic() +
  theme(legend.position = c(0.25, 0.17), legend.title = element_text(face = "bold", size = 16), legend.text = element_text(size = 20),
        title = element_text(size = 23),
        axis.title.x = element_text(size = 25, margin = margin(t = 10, r = 0, b = 0, l = 0)),
        axis.title.y = element_text(size = 25, margin = margin(t = 0, r = 12, b = 0, l = 0)),
        axis.text = element_text(size = 25, color = "black"), axis.line = element_line(size = 1), axis.ticks = element_line(size = 1))

Survival Analysis

Clinical Conversion into Dementia ~ Top 20 protein teritile + Age + Sex + Disease Duration

setwd('/Users/junchaoshen/UPenn BMI')
survival.upenn = read.csv('Survival Analysis Replication.csv')
kable(survival.upenn[1:5,], "html") %>% kable_styling("striped") %>% scroll_box(width = "100%")

INDDID	DRSTotal	BL.DRS	TestDate	SampleDate	Event	DaysVisitToSample	TimeMonth	AgeAtTest	AgeAtSample	DieseaseDuration	YOB	Sex	LEDD_x	Group	a1.Antitrypsin	a2.Antiplasmin	a2.HS.Glycoprotein	a2.Macroglobulin	ABL1	ACE2	ACTH	Activated.Protein.C	Activin.A	Activin.AB	ADAM.9	ADAM12	ADAMTS.4	ADAMTS.5	Adiponectin	Afamin	Aflatoxin.B1.aldehyde.reductase	Aggrecan	AIF1	AIP	AK1A1	Albumin	ALCAM	ALK.1	Alkaline.phosphatase.bone	ALT	AMHR2	Aminoacylase.1	AMNLS	AMPK.a1b1g1	AMPK.a2b2g1	AMPM2	amyloid.precursor.protein	AN32B	Angiogenin	Angiopoietin.1	Angiopoietin.2	Angiopoietin.4	Angiostatin	Angiotensinogen	ANGL3	ANGL4	annexin.I	annexin.II	annexin.VI	Antithrombin.III	Apo.A.I	Apo.B	Apo.D	Apo.E	Apo.E3	Apo.E4	AREG	ARGI1	ARI3A	ARMEL	ARP19	ARSB	ART	Artemin	ARTS1	Arylsulfatase.A	ASAH2	ASAHL	ASGR1	ASM3A	ATS1	ATS13	ATS15	AURKB	Aurora.kinase.A	Azurocidin	b.ECGF	b.Endorphin	b.NGF	b2.Microglobulin	B7.2	B7.H1	B7.H2	BAFF	BARK1	BCAM	Bcl.2	BCL2.like.1.protein	BCMA	BDNF	bFGF	BFL1	BGH3	BGN	BLC	BMP.1	BMP.7	BMP.RII	BMPER	BMPR1A	BMX	BNP.32	BOC	Bone.proteoglycan.II	BPI	BSP	BSSP4	BST1	BTK	C1.Esterase.Inhibitor	C1r	C1s	C2	C34.gp41.HIV.Fragment	C3d	C5	C5a	C5b.6.Complex	C7	C8	C9	Cadherin.2	Cadherin.5	Cadherin.E	Calcineurin	calgranulin.B	Calpain.I	Calpastatin	CAMK2A	CAMK2B	CAMK2D	CaMKK.alpha	CAPG	Carbonic.anhydrase.6	Carbonic.anhydrase.9	Carbonic.anhydrase.I	carbonic.anhydrase.II	Carbonic.anhydrase.III	Carbonic.Anhydrase.IV	Carbonic.anhydrase.VII	Carbonic.Anhydrase.X	Carbonic.anhydrase.XIII	Caspase.10	Caspase.2	Caspase.3	Catalase	CATE	Cathepsin.A	Cathepsin.B	Cathepsin.D	Cathepsin.H	Cathepsin.S	Cathepsin.V	CATZ	CBPE	CCL28	CD109	CD22	CD226	CD23	CD30.Ligand	CD36.ANTIGEN	CD40.ligand.soluble	CD48	CD5L	CD70	CD97	CDC37	CDK1.cyclin.B	CDK2.cyclin.A	CDK5.p35	CDK8.cyclin.C	CDON	CFC1	Chitotriosidase.1	Chk2	CHL1	CHST6	cIAP.2	Ck.b.8.1	CK.BB	CK.MB	CK.MM	CK2.A1.B	CK2.A2.B	CLC1B	CLC4K	CLF.1.CLC.Complex	CLM6	CNDP1	CNTF	CNTFR.alpha	CNTN2	CO8A1	Coagulation.Factor.IX	Coagulation.Factor.IXab	Coagulation.Factor.VII	Coagulation.Factor.X	Coagulation.Factor.XI	Cofilin.1	Collectin.Kidney.1	COMMD7	complement.factor.H.related.5	CONA1	contactin.1	Contactin.4	Contactin.5	COX.2	CPNE1	CRDL1	Cripto	CRK	CRP	CRTAM	CSF.1	CSK	CSK21	CTACK	CTAP.III	CTGF	CTLA.4	CXCL16.soluble	Cyclin.B1	Cyclophilin.A	Cyclophilin.F	Cystatin.C	Cystatin.M	CYTD	CYTF	CYTN	Cytochrome.c	Cytochrome.P450.3A4	CYTT	D.dimer	DAF	DAN	DAPK2	DBNL	DC.SIGN	DcR3	DEAD.box.protein.19B	DERM	Desmoglein.2	DHH	discoidin.domain.receptor.1	Dkk.4	DKK1	DKK3	DLC8	DLL1	DLRB1	DMP1	DnaJ.homolog	dopa.decarboxylase	DR3	DR6	DRAK2	DRG.1	DRR1	DSC3	Dtk	DUS3	Dynactin.subunit.2	ECM1	EDA	EDAR	EF.1.beta	EG.VEGF	eIF.5	eIF.5A.1	Elafin	Elastase	EMAP.2	EMR2	Endocan	Endoglin	Endostatin	Endothelin.converting.enzyme.1	ENPP7	Enterokinase	ENTP5	Eotaxin	EP15R	EphA1	EPHA3	EphA5	EPHAA	EPHB2	EphB6	Ephrin.A4	Ephrin.A5	Ephrin.B3	EPI	Epithelial.cell.kinase	EPO.R	ER	ERBB1	ERBB2	ERBB3	ERBB4	ERK.1	ESAM	Esterase.D	ETHE1	FABP	FABPE	Factor.B	Factor.I	FAK1	FAM107B	Fas.ligand.soluble	FCAR	FCG2A.B	FCG3B	FCGR1	FCN1	FCN2	FCRL3	FER	Ferritin	FETUB	FGF.10	FGF.12	FGF.16	FGF.18	FGF.19	FGF.20	FGF.4	FGF.5	FGF.6	FGF.8A	FGF7	FGFR.2	FGFR.3	FGFR4	FGR	Fibrinogen	Fibrinogen.g.chain.dimer	Ficolin.3	FLRT1	Flt.3	Flt3.ligand	FN1.4	Fractalkine.CX3CL.1	FSH	FST	FSTL3	Fucosyltransferase.3	FUT5	FYN	G.CSF.R	GA733.1.protein	Galectin.2	Galectin.3	Galectin.4	Galectin.8	GAPDH.liver	GASP.2	GCKR	GCP.2	GDF.11	GDF.9	GDF2	Gelsolin	GFAP	GFRa.1	GFRa.2	GIB	GIIE	GITR	Glucagon	Glucocorticoid.receptor	Glutamate.carboxypeptidase	Glutathione.S.transferase.Pi	Glypican.3	GM.CSF	GNS	GOT1	gp130.soluble	GP1BA	GPC2	GPC5	gpIIbIIIa	GPNMB	GPVI	Granulysin	granzyme.A	Granzyme.B	Granzyme.H	GRN	Gro.a	Gro.b.g	Growth.hormone.receptor	GSK.3.alpha.beta	GV	H6ST1	HAI.1	Haptoglobin.Mixed.Type	Hat1	HCC.1	HCC.4	HCG	HCK	HDAC8	HDGR2	Hemopexin	Heparin.cofactor.II	HGF	HGFA	HINT1	HIPK3	Histone.H1.2	Histone.H2A.z	HIV.2.Rev	HMG.1	HMGR	hnRNP.A.B	hnRNP.A2.B1	hnRNP.K	HNRPQ	HO.2	HPG.	HPLN1	HPV.E7.Type.16	HRG	HSP.40	HSP.60	HSP.70	HSP.90a.b	HTRA2	HVEM	I.309	I.TAC	ICOS	IDE	IDS	IDUA	IF4A3	IFN.g	IFN.g.R1	IFN.lambda.1	IFN.lambda.2	IgD	IgE	IGF.I	IGF.I.sR	IGF.II.receptor	IGFBP.1	IGFBP.2	IGFBP.3	IGFBP.4	IGFBP.5	IGFBP.6	IGFBP.7	IgG	IgM	IL.1.R.AcP	IL.1.R4	IL.1.sRI	IL.10	IL.11	IL.11.RA	IL.12.Rb1	IL.12.RB2	IL.13	IL.13.Ra1	IL.15.Ra	IL.16	IL.17	IL.17.RC	IL.17.RD	IL.17.sR	IL.17B	IL.17B.R	IL.17D	IL.17E	IL.17F	IL.18.BPa	IL.18.Ra	IL.19	IL.1a	IL.1F7	IL.1Rrp2	IL.2	IL.2.sRa	IL.2.sRg	IL.20	IL.20.Ra	IL.22	IL.22BP	IL.23	IL.23.R	IL.27	IL.3	IL.3.Ra	IL.34	IL.4	IL.4.sR	IL.5.Ra	IL.6	IL.6.sRa	IL.7	IL.7.Ra	IL.8	IL22RA1	IL24	ILT.2	ILT.4	IMB1	IMDH1	IMDH2	ING1	Insulin	Integrin.a1b1	Integrin.aVb5	IP.10	IR	ITI.heavy.chain.H4	JAG1	JAG2	JAK2	JAM.B	JAM.C	JAML1	JNK2	K.ras	Kallikrein.11	kallikrein.12	kallikrein.13	Kallikrein.4	kallikrein.5	Kallikrein.6	Kallikrein.7	kallikrein.8	Kallistatin	Karyopherin.a2	Keratin.18	KI2L4	KI3L2	KI3S1	KIF23	Kininogen.HMW	KIRR3	KLRF1	KPCI	KPCT	KREM2	Ku70	KYNU	Lactoferrin	LAG.1	LAG.3	Lamin.B1	Laminin	Layilin	LBP	LCK	LCMT1	LD78.beta	LDH.H.1	LEAP.1	Leptin	LG3BP	LIF.sR	LIGHT	LIMP.II	LIN7B	Lipocalin.2	LKHA4	LRIG3	LRP8	LRRT1	LRRT3	LSAMP	Luteinizing.hormone	LY86	LY9	Lymphotactin	Lymphotoxin.a1.b2	Lymphotoxin.a2.b1	Lymphotoxin.b.R	LYN	LYNB	Lysozyme	LYVE1	M2.PK	Macrophage.mannose.receptor	MAPK14	MAPK2	MAPK5	MAPKAPK3	MASP3	MATK	MATN2	MBD4	MBL	MCP.1	MCP.3	MCP.4	MDC	MDHC	MDM2	MED.1	MEPE	Mesothelin	Met	METAP1	MFGM	MFRP	MIA	MICA	MICB	Midkine	MIF	MIP.1a	MIP.3a	MIP.3b	MIP.5	MIS	MK01	MK08	MK11	MK12	MK13	MMP.1	MMP.10	MMP.12	MMP.13	MMP.14	MMP.2	MMP.3	MMP.7	MMP.8	MMP.9	Mn.SOD	MO2R1	Moesin	MP2K2	MP2K4	MPIF.1	MRC2	MSP	Myeloperoxidase	Myoglobin	Myokinase.human	NACA	NADPH.P450.Oxidoreductase	NAGK	NANOG	NAP.2	NCAM.120	NCAM.L1	NCC27	NCK1	NDP.kinase.B	Nectin.like.protein.2	NET4	Neurotrophin.3	Neurotrophin.5	NG36	NID2	Nidogen	NKG2D	NKp30	NKp46	NLGNX	NMT1	Nogo.Receptor	NOTC2	Notch.1	Notch.3	NovH	NPS.PLA2	Nr.CAM	NR1D1	NRP1	NRX1B	NRX3B	NSF1C	NUDC3	NXPH1	OCAD1	Olfactomedin.4	OLR1	OMD	ON	OPG	OX2G	P.Selectin	p27Kip1	PA2G4	PACAP.38	PAFAH	PAFAH.beta.subunit	PAI.1	PAK3	PAK7	PAPP.A	paraoxonase.1	PARC	PARK7	PBEF	PCNA	PCSK7	PCSK9	PD.L2	PDE11	PDE3A	PDE5A	PDE7A	PDGF.AA	PDGF.BB	PDGF.CC	PDGF.Rb	PDK1	PDPK1	Periostin	PERL	Peroxiredoxin.1	Peroxiredoxin.6	Persephin	PESC	PF.4	PFD5	PGCB	PGP9.5	PGRP.S	PH	PHI	phosphoglycerate.kinase.1	Phosphoglycerate.mutase.1	PIGR	PIK3CA.PIK3R1	PKB.a.b.g	PKC.A	PKC.B.II	PKC.Z	Plasmin	Plasminogen	PLCG1	PlGF	PLK.1	PLPP	PLXC1	PPAC	PPase	PPID	PPIE	Prekallikrein	PRKACA	PRL	Prolactin.Receptor	prostatic.binding.protein	Protease.nexin.I	Protein.C	Protein.disulfide.isomerase	Protein.disulfide.isomerase.A3	Proteinase.3	PSA	PSA.ACT	PSA1	PSA2	PSA6	PSD7	PSMA	PSME1	PSME3	pTEN	PTH	PTHrP	PTK6	PTN	PTP.1B	PTP.1C	PYY	Rab.GDP.dissociation.inhibitor.beta	RAC1	RAD51	RAN	RANTES	RAP	Rb	RBM39	RBP	RELT	Renin	resistin	RET	RGM.C	RGMA	RGMB	ROBO2	ROBO3	ROR1	RPS6KA3	RS3	RS7	RSK.like.protein.kinase	RSPO2	RTN4	RUXF	SAA	SAP	SARP.2	SBDS	sCD163	sCD4	SCF.sR	SCGF.alpha	SCGF.beta	SDF.1	sE.Selectin	SE6L2	Secretin	Semaphorin.3A	Semaphorin.3E	Semaphorin.6A	SEPR	SET	sFRP.3	SGTA	SH21A	SHBG	SHC1	SHP.2	Sialoadhesin	sICAM.1	sICAM.2	sICAM.5	SIG14	Siglec.3	Siglec.6	Siglec.7	Siglec.9	SKP1	sL.Selectin	SLAF6	SLAF7	sLeptin.R	SLIK5	SLPI	SNAA	SOD	Somatostatin.28	Sonic.Hedgehog	SORC2	Sorting.nexin.4	SP.D	SPARCL1	Sphingosine.kinase.1	SPHK2	SPINT2	Spondin.1	SPTA2	sRAGE	sRANKL	SRCN1	SREC.I	SREC.II	SSRP1	ST4S6	Stanniocalcin.1	sTie.1	sTie.2	STRATIFIN	Stress.induced.phosphoprotein.1	STX1a	suPAR	TAFI	TAJ	TAK1.TAB1	TARC	tau	TBK1	TBP	TCCR	TCPTP	TCTP	TEC	TECK	Tenascin	Testican.1	Testican.2	TF	TFF3	TFPI	TGF.b.R.II	TGF.b.R.III	TGF.b1	TGF.b2	Thrombin	Thrombopoietin.Receptor	Thrombospondin.1	Thymidine.kinase	Thyroglobulin	Thyroxine.Binding.Globulin	TIG2	TIMD3	TIMP.1	TIMP.2	TIMP.3	TLR4.MD.2.complex	TNF.a	TNF.b	TNF.sR.I	TNF.sR.II	TNFSF15	TNFSF18	TNR4	Topoisomerase.I	tPA	TPSB2	TPSG1	TRAIL.R4	transcription.factor.MLR1.isoform.CRA_b	Transketolase	TrATPase	Triosephosphate.isomerase	TrkA	TrkB	TrkC	Tropomyosin.1.alpha.chain	Tropomyosin.2	TRY3	Trypsin	Trypsin.2	TS	TSG.6	TSH	TSLP	TSLP.R	TSP2	TSP4	TWEAK	TWEAKR	TXD12	UB2L3	UBC9	UBE2N	Ubiquitin.1	UFC1	UFM1	ULBP.1	ULBP.2	ULBP.3	UNC5H3	UNC5H4	uPA	URB	Vasoactive.Intestinal.Peptide	VCAM.1	VEGF	VEGF.C	VEGF.sR2	VEGF.sR3	VEGF121	WFKN2	WIF.1	WNT7A	X14.3.3	X3HIDH	X4.1BB	X4.1BB.ligand	X41	X4EBP2	X6.Phosphogluconate.dehydrogenase	X6Ckine	XEDAR	XPNPEP1	XTP3A	YES	ZAP70	Fast.Progression
100080	142	141	2/17/2015	5/3/2010	0	1751	57.4	68	64	9	1946	Female	1358	PD	2.770263	3.352511	3.179236	3.846733	2.303628	2.814714	2.601408	3.090399	3.901742	2.547036	3.290235	2.760498	2.581722	2.564903	3.822332	4.593109	3.462503	2.955592	3.459784	3.827369	3.574818	4.030539	4.076972	3.370032	4.949672	3.610894	5.152935	3.560648	2.755418	2.736237	3.491558	4.371088	4.057202	2.190892	3.609370	2.638888	2.824972	2.610554	3.958975	3.257294	2.857031	3.409104	4.370260	3.925771	3.974576	4.869780	4.172810	4.097431	3.834096	4.209459	5.140156	5.007874	3.451648	2.987175	2.847141	3.522744	2.894150	3.010893	3.300943	2.846832	5.144554	2.827369	3.568331	3.822835	2.479287	3.759434	2.405005	3.540430	2.580925	3.033946	3.360896	2.524266	2.528274	2.769968	2.616370	3.015234	2.891035	3.248954	2.967267	3.043559	3.904445	3.242517	3.193403	3.103735	3.374070	2.839478	3.078855	3.083646	4.488689	3.716195	3.442339	3.142765	2.943742	2.746556	2.419129	2.692583	2.749350	2.574031	3.205231	3.459030	3.222222	3.310205	3.136562	3.836153	3.729675	4.168830	3.123362	3.909021	3.277701	2.976029	2.694078	3.818094	4.179489	2.791410	3.253023	3.622618	4.851012	3.297957	3.731323	4.714093	3.294554	4.162352	4.480692	4.077470	3.014226	3.437053	3.713575	2.431203	3.257271	2.775902	2.863323	4.610004	2.416141	4.099605	3.369828	2.179264	3.022181	3.346373	3.536748	2.565021	3.880282	4.362795	2.221153	3.619125	3.091210	3.363950	3.401556	2.816573	3.317332	3.464326	3.346979	3.697474	3.701637	3.130912	3.048752	3.677333	3.343901	4.305186	2.390759	2.743039	3.435956	3.358239	3.340860	2.537945	2.656002	2.677151	3.232335	3.242715	3.768749	3.196618	3.065131	2.255031	3.968086	2.399501	2.294025	4.738297	2.805161	3.407646	3.263068	4.071584	2.845842	4.211854	2.235528	2.659060	3.487350	4.437007	2.551328	4.101163	3.084004	2.696968	4.188174	4.011012	2.937217	4.108054	3.440358	4.156637	3.880276	3.476034	2.885474	2.578066	2.694166	3.751818	2.789016	3.270981	3.484072	3.543373	2.611829	4.048888	4.073902	2.797752	3.211974	3.732088	2.842360	3.191647	4.130073	3.419295	2.322426	4.095699	2.582063	5.020362	3.988728	3.340543	3.730572	3.565293	2.787744	3.114044	3.286838	4.277114	4.105922	4.192629	4.184652	3.129497	3.515384	3.238071	3.416607	2.855943	3.019324	3.354051	4.786744	2.957176	2.406370	3.702784	4.049233	3.693120	2.784974	3.155852	3.774765	2.477700	2.763578	2.636488	3.972712	3.878826	4.177202	4.490786	2.601625	2.638090	3.164353	3.357801	2.671173	4.401039	3.315529	3.007065	3.185117	2.525692	3.398600	3.966123	3.740339	2.658870	3.715853	2.525045	3.016783	3.298657	4.686290	4.284054	3.435908	2.263636	3.685643	4.053708	2.668759	3.875698	2.156246	2.944779	2.590173	4.140153	3.259880	3.111498	3.645009	2.845656	3.218352	3.621187	2.439333	3.110825	4.567138	2.502700	2.841735	2.044932	4.485311	3.391464	4.115058	3.508018	3.452645	2.871456	4.338638	4.780559	2.294025	3.424669	2.810837	2.247237	3.615950	3.158061	2.411788	3.902601	4.010978	2.777499	2.938820	2.931153	3.706846	2.310056	2.353916	3.332075	2.560146	3.924450	2.700098	2.384353	3.208334	2.732715	2.370328	3.154880	2.792672	2.721646	3.017576	2.695307	5.133902	4.832668	3.140319	2.903578	3.614887	2.891259	4.724772	3.791248	3.917006	2.912860	3.825433	2.634377	3.899656	3.748638	2.849296	2.678609	2.767898	4.104070	3.101541	2.565376	4.844418	2.760875	2.757244	3.395955	2.763653	3.097604	3.269583	3.166134	2.828853	3.187605	3.906615	2.862310	2.369030	2.771955	3.246843	1.971276	3.089693	3.974480	3.039335	4.101396	3.558301	3.845575	4.054307	3.004020	2.375846	2.839227	4.073311	3.996936	3.743690	3.263944	3.385141	2.271842	2.440594	4.436810	3.496362	2.866169	2.980549	4.023248	2.575419	2.407051	4.021913	3.856312	2.409933	3.983207	4.249223	3.875287	2.276232	3.458063	2.854245	2.631849	3.244500	2.956649	3.725430	3.596916	2.924124	3.317436	3.307475	2.219060	4.661780	2.572872	3.649179	4.129151	2.368844	3.423704	2.623559	3.436401	3.057666	2.144574	3.381205	2.673113	4.027778	4.007167	4.498002	3.603188	2.638888	3.662437	3.415040	2.856729	3.667322	3.727004	2.938720	2.781109	2.955351	2.656098	2.468052	2.255996	2.695044	3.796484	3.190864	3.932930	4.531996	2.724522	4.709845	3.144574	3.957933	3.293583	2.945075	4.659200	4.463901	3.437069	4.850639	3.221727	3.745535	2.608954	2.419956	3.885819	2.534153	2.960090	2.903144	3.564974	3.028531	3.681648	2.287130	3.020734	2.697055	2.522183	2.423082	3.316934	2.617839	2.672652	2.994757	3.886959	3.920869	3.968511	2.948071	3.200194	2.985157	3.255272	2.960566	3.528029	2.661623	2.591176	3.048481	3.483758	2.434888	3.303606	3.045597	3.208334	2.809829	2.919706	2.603144	2.586587	3.044775	2.512951	4.364224	2.449478	2.626443	3.099853	2.749659	2.372175	3.581563	3.986906	4.082214	3.600068	3.527037	3.918251	2.085647	3.017117	3.102125	3.231826	3.988728	4.360896	3.197501	2.683227	4.193345	3.778310	3.505638	2.712902	2.609701	2.983987	2.871573	3.794132	3.208226	2.503246	2.550106	3.609904	2.973313	3.467194	4.745446	2.671543	2.575765	3.337619	3.504770	2.668293	2.955495	4.560745	2.521922	2.619615	3.394417	3.431010	3.333890	2.569491	2.831742	4.760028	2.759668	4.165188	2.882809	3.242790	3.244129	4.240067	2.749968	3.537806	3.452109	3.266631	3.876720	3.876247	2.748808	2.423737	2.745465	2.557387	2.622421	3.675201	2.956409	3.966461	3.389875	1.987219	2.167317	3.243460	3.645501	3.767712	3.576099	2.670060	2.311966	3.448165	3.846547	3.716529	4.417447	4.544933	2.696793	4.320090	3.730782	3.121790	3.765236	3.182243	3.096215	3.758632	2.402261	4.180278	2.909663	3.992297	2.741545	2.949975	2.717004	3.062507	4.457706	2.415307	2.698449	2.380392	2.810098	4.160454	3.339272	2.860458	2.934700	3.564654	2.604766	2.522575	4.145631	3.178545	3.064720	2.299725	2.811642	3.747777	4.214849	3.971188	3.113241	2.729084	2.866405	3.113208	2.625107	2.557868	3.062544	2.775829	3.029952	3.505638	3.006766	3.093176	3.020982	4.462254	4.658439	3.118959	3.152930	3.673436	4.789697	3.320312	3.320603	3.530993	4.291819	3.455804	4.569796	3.870140	3.402485	2.737272	2.307282	3.423737	4.085080	2.727216	3.657992	2.972110	4.069783	3.388403	2.945469	2.574957	2.307710	3.359038	3.306939	3.415124	2.874772	2.663418	3.440594	2.780749	3.659289	3.244623	2.670524	4.256145	2.966095	2.897187	3.625004	4.258441	2.554731	2.811106	2.970068	3.000521	2.829175	2.746167	4.157910	3.073572	2.251151	3.425387	4.026190	4.185613	4.220474	3.541479	3.757411	3.225516	3.268625	2.739651	3.157698	3.561995	2.575188	3.206772	2.960423	3.877866	2.333246	3.743643	2.998956	3.059033	2.180413	3.333387	3.050766	3.571744	3.341632	3.339173	4.224352	2.553155	3.438590	4.275664	2.686189	4.019926	3.405654	3.301247	3.436910	2.815910	3.427324	2.853211	2.347330	2.617943	4.282572	2.705179	3.094890	3.254113	2.765743	3.437608	4.323089	3.704288	3.036629	3.517037	3.009833	3.509941	4.309394	3.723127	3.000391	2.828789	3.312918	2.790567	2.594613	2.269279	3.536987	2.910838	3.351487	4.525958	3.389644	3.073865	4.735920	3.797766	2.915716	3.357535	3.890605	3.393171	3.252416	2.337260	3.800738	3.276554	2.351603	3.897616	2.905850	2.887842	2.809829	2.623972	3.455925	3.207877	2.489255	2.754654	2.257679	2.970300	2.479143	3.120146	3.613937	3.770557	2.896967	4.434812	4.220477	3.460823	3.573857	3.744011	3.023211	3.170907	2.821645	3.022305	3.071845	3.053885	2.992863	3.036669	3.976762	4.444032	3.271726	3.585709	2.519172	3.061566	3.181043	3.212880	3.655676	2.511883	2.579441	4.912427	4.034580	3.683110	4.593013	3.578261	3.789404	3.414622	2.622318	4.299185	3.336059	2.982904	3.776534	4.620360	3.163966	2.464042	2.885191	3.468834	4.178594	2.985516	2.843793	3.626597	3.284724	3.264936	3.672126	3.930674	3.799113	2.042182	3.757624	2.952744	2.747645	4.206656	3.555143	2.162266	3.054498	4.334116	3.442636	3.812231	2.684127	4.593084	3.248047	3.569210	4.346296	3.828641	3.186221	2.694517	3.128011	2.428459	3.855519	4.738237	4.200100	3.876108	2.685921	3.069261	3.287936	2.250176	2.986234	3.329947	4.277488	3.717338	2.934852	2.848312	3.552157	3.372691	3.992408	3.310884	2.942455	3.920363	2.789369	3.862459	4.329361	3.069520	3.514189	3.123492	2.983626	2.714414	2.894538	3.203414	2.745075	3.996297	3.458895	3.384998	4.318656	3.417787	2.875409	3.153632	3.706709	4.903336	3.132292	4.474480	3.261881	2.394452	3.370975	2.546543	2.925724	2.974926	2.236033	4.710877	3.516284	3.842210	2.584331	2.843295	2.833657	3.707298	2.665206	2.678154	3.097153	3.969388	3.309140	2.819478	2.740915	3.274666	2.631342	3.583618	2.434888	5.049151	2.439333	4.618307	3.856294	3.861714	3.264582	2.875177	3.520208	2.904553	3.419791	2.730540	3.989463	3.019116	2.681874	3.098055	2.790144	2.431525	3.438938	4.081452	2.957176	2.391112	2.637890	3.260286	3.301854	3.482430	3.728695	4.225260	4.294089	3.618121	3.269723	2.473049	3.104862	3.590028	3.923627	3.538046	3.429106	2.499687	3.881727	4.187783	2.863382	3.975703	3.880213	2.665675	3.820911	3.492467	2.498173	3.887291	2.781684	2.520876	2.401400	4.426150	2.374198	3.973373	3.930842	3.251419	3.927406	4.182760	3.089658	3.876760	0
100528	131	140	1/29/2013	12/3/2010	1	788	0.0	75	75	16	1935	Female	2180	PD	2.953615	3.322839	3.101094	4.000143	2.205204	2.945715	2.532117	2.794767	3.873001	2.632153	3.397905	2.744918	2.605413	2.818885	3.661065	4.604507	3.431219	2.874250	3.387230	3.601517	3.600090	4.090085	4.098910	3.374345	4.810286	3.558084	5.140581	3.490997	2.649237	2.713407	3.537718	4.388094	3.984599	2.136403	3.647755	2.652343	2.871281	2.685563	3.954421	3.278205	2.829882	3.368863	4.088303	3.870784	3.657887	4.839094	3.986073	4.017159	3.779373	4.245115	5.150750	5.003920	3.586238	3.016950	2.833848	3.538599	2.685742	3.200659	3.407985	2.798858	4.641329	2.837210	3.599053	3.874267	2.604010	3.668991	2.433610	3.626505	2.539327	3.044461	3.133028	2.614686	2.402605	2.664172	2.566909	3.140665	2.904553	3.165007	2.943445	3.268859	3.543969	3.312135	3.288294	3.095413	3.546950	2.720573	2.925106	3.113040	4.469143	3.711166	3.837001	3.146407	2.960043	2.747878	2.507046	2.638888	2.745543	2.532117	3.444794	3.594801	2.737590	3.621239	3.266349	3.905391	3.447561	3.845334	2.980140	3.851387	2.942306	3.183156	2.621280	3.783775	3.860206	2.778224	3.386535	3.669001	4.944955	3.315698	3.677004	4.735628	3.055493	4.123433	4.462738	4.104839	2.846275	3.192874	3.518540	2.436163	3.218982	3.311351	3.046339	4.750996	2.242541	3.995569	3.399483	2.190332	3.034829	3.231342	3.510397	2.458789	3.806356	4.479231	2.238548	3.723554	3.232335	3.429251	3.520523	2.933234	3.425371	3.597684	3.516879	3.802021	3.931366	3.182186	3.033745	3.767431	3.505747	3.995442	2.412460	3.007364	3.881328	3.464609	3.380374	2.473487	2.713154	2.740757	3.257246	3.191647	3.712414	3.250347	3.356752	2.265996	3.965719	2.421110	2.290702	4.857018	2.873204	3.260191	2.901186	4.183176	2.936866	3.967173	2.225826	2.617420	3.638339	4.057700	2.551206	4.061566	2.852663	2.789299	4.214006	4.040163	2.836451	4.044301	3.284634	3.942097	3.718178	3.357954	2.795602	2.519434	2.681874	3.786730	2.650793	2.901949	3.435876	3.747155	2.582063	4.027019	4.098152	2.775028	3.281783	3.351584	2.990161	3.147584	3.737590	3.230857	2.201943	3.972453	2.603361	4.923090	3.717978	3.489959	3.862507	4.083667	3.080771	3.210479	3.219532	4.130031	4.219364	4.169460	4.135327	3.305803	3.554756	3.149773	3.222300	2.642069	2.770115	3.612784	4.794868	3.035950	2.402261	3.909085	4.138808	3.707621	2.747334	3.273626	3.381025	2.471878	2.782616	2.588272	4.007137	3.873117	3.856300	4.535131	2.680879	2.411788	3.128787	3.067703	2.772395	4.344259	3.317792	2.918712	3.259188	2.501333	3.407442	4.048737	4.034781	2.710963	3.605456	2.523747	3.233326	3.238924	4.763947	4.418979	3.193653	2.231724	3.746619	4.338349	2.635081	3.935729	1.992554	2.806926	2.564548	4.256133	3.306146	3.192540	3.693481	2.871748	2.939918	3.587767	2.459845	3.024198	4.381577	2.646404	2.754195	2.090258	4.298023	3.410170	4.003448	3.495086	3.387586	3.048170	4.188279	4.724608	2.252368	3.252489	2.829947	2.267172	3.912286	3.325885	2.442950	3.938695	3.826884	2.870989	2.608526	3.126781	3.419443	2.283527	2.135769	3.436767	2.443420	4.397886	2.590730	2.411620	2.671913	2.807197	2.362483	3.276370	2.292478	2.765594	3.097916	2.564666	5.102796	4.810953	2.979093	2.960661	3.574159	2.806383	4.750043	3.868186	3.918973	2.899328	3.901257	2.846151	3.789771	3.388350	2.830717	2.782902	2.647579	4.121662	3.128270	2.517460	4.823175	3.040681	2.940865	3.418517	2.780821	2.932677	3.181815	3.172223	2.920697	3.354819	3.916338	3.088526	2.360025	2.818160	3.427340	2.028164	3.041590	3.941437	2.909396	2.734560	3.462518	3.711225	4.031986	2.936966	2.335659	2.894316	3.737781	3.958998	3.619125	3.287354	3.545221	2.254790	2.449015	4.554033	3.431364	2.804889	2.804003	3.923280	2.543944	2.423410	4.082785	3.877901	2.455758	4.137288	4.536215	4.278056	2.266467	3.424931	2.757168	2.676511	3.193737	3.130366	3.599774	2.460748	2.989806	2.605305	3.108869	2.224015	4.106524	2.452093	3.417339	3.614127	2.462248	3.416774	2.512551	3.337519	3.095344	2.172019	3.181472	2.698536	3.828692	4.044696	4.293493	3.560194	2.655427	3.694860	3.586745	2.818951	3.910128	3.720118	3.111027	2.840043	3.039216	2.614792	2.389875	2.235276	2.430559	3.011232	3.205556	4.009918	4.439437	2.975110	4.954028	2.999348	3.987438	3.227758	3.036589	4.784499	4.344194	4.030284	4.626559	3.535914	3.719016	2.606059	2.431846	3.871993	2.647285	3.051037	2.873379	3.484997	3.043441	3.374602	2.307496	3.102365	2.686547	2.553276	2.411956	3.289277	2.794000	2.561817	3.017117	4.082495	4.155631	3.844937	2.760724	3.282781	3.066810	3.306168	3.017701	3.621072	2.686547	2.523486	3.305480	3.836008	2.378761	3.374803	3.340226	3.252683	2.887786	2.947140	2.629817	3.261762	3.516125	2.677881	4.547339	2.237292	2.521530	3.069187	2.714246	2.303844	3.658946	4.074937	4.036677	3.465472	3.468776	3.807467	2.067071	2.854306	3.720631	3.418119	3.931280	4.328347	3.200550	2.689220	4.193728	3.849100	3.584060	2.722058	2.730298	2.991448	3.175802	3.921031	3.282894	2.509471	2.409595	3.642237	3.072544	3.552096	4.798321	2.675045	2.613736	3.399241	2.737590	2.660106	2.988024	4.629223	2.461949	2.603686	3.482030	3.231699	3.381025	2.053078	3.075875	4.709528	2.858778	4.280089	2.870697	3.350945	3.278319	4.561764	2.631342	3.490239	3.516020	3.181472	3.392152	3.615055	2.925518	2.950462	2.693199	2.550228	2.568788	3.951104	2.906335	3.919230	3.352183	2.017451	2.156246	3.285107	3.493458	3.696880	3.620927	2.564311	2.332438	3.508435	3.864292	3.406591	4.099256	4.760589	2.506911	4.086314	3.617032	2.942306	3.573324	2.788381	2.614264	3.759668	2.369587	4.179675	2.868115	3.997330	2.670524	2.858658	2.479719	3.221701	4.500810	2.351023	2.665581	2.384353	2.729327	4.027093	3.216113	3.089764	2.946108	3.626114	2.489677	2.743980	5.654998	3.198932	3.034629	2.250908	3.172865	3.602722	4.259264	3.901605	2.785472	2.805093	2.729327	2.767601	2.850095	2.619406	3.083932	2.980957	3.083180	3.525408	3.657419	3.411249	3.020403	4.456987	4.513250	3.057970	2.930134	3.361520	4.493492	3.346294	3.267547	3.640531	4.507467	3.288696	4.719031	3.946197	3.502536	3.000824	2.293804	3.101678	3.915695	2.641474	3.466764	3.336099	4.003839	3.310948	2.997605	2.590730	2.282622	3.279051	3.247482	3.336059	2.908646	2.653984	3.576940	2.946157	3.398131	3.417555	2.734400	4.249262	2.941263	2.870638	3.709829	4.221380	2.521007	2.975294	2.934397	3.088774	2.857935	2.649237	3.896702	3.051037	2.166430	3.460040	4.031138	4.024100	4.245026	3.527913	3.597882	3.159116	3.386303	2.746245	3.068074	3.737733	2.480151	3.237192	2.970626	4.394056	2.251151	3.852943	2.755341	2.881385	2.122216	3.495905	3.068631	3.636347	3.266114	3.361822	3.970393	2.596157	3.285152	3.979735	2.615529	4.097740	3.285107	2.915558	3.469056	3.122609	3.626915	3.033223	2.348500	2.569140	3.826554	2.748498	3.090787	3.131330	2.924124	3.144885	4.170558	3.769311	2.965578	3.703610	2.960185	3.329255	3.984797	3.364514	2.920436	2.777354	3.323541	2.693375	2.588832	2.261976	3.641831	3.082031	3.965503	4.527328	3.204608	3.093352	4.574318	3.422327	2.898780	3.367263	3.949151	3.230985	3.227527	2.397592	3.626812	3.596817	2.342225	3.985031	2.958755	2.848989	2.912860	2.486005	3.482245	3.113876	3.623167	2.618780	2.629613	2.914766	2.403464	3.436735	3.533848	3.446149	3.023869	4.492864	4.101675	3.517869	3.864517	3.639546	3.022057	3.174263	2.451479	3.063521	3.214870	2.809021	3.286164	2.960090	3.947007	4.437820	2.981909	3.571115	2.520352	3.161338	2.948755	2.697316	2.988648	2.529815	2.625313	4.719207	3.416624	2.413132	4.487780	3.536987	3.636347	3.512444	2.669224	4.062386	3.405312	3.054000	3.856469	4.322296	3.230372	2.433450	2.950949	3.540955	4.204351	2.886716	2.797960	3.794871	3.359513	2.848374	3.976465	3.871620	3.684531	2.147985	3.673694	3.035310	2.724358	4.424030	3.736006	2.201124	3.061829	2.465977	3.524850	3.915046	2.797406	4.588726	3.525447	3.578295	4.501560	3.839830	3.214552	2.677789	3.155306	2.444201	3.599665	4.072397	4.186987	3.592676	2.663324	3.163787	3.509270	2.182415	2.871223	3.343527	3.913427	3.760287	2.735759	2.585009	3.641781	3.324344	3.940835	3.331852	2.959661	3.930985	2.681603	3.987367	4.328461	3.108057	3.433690	3.001258	2.967361	2.744215	2.661245	3.249247	2.704236	3.844937	3.396565	3.353031	4.518424	3.371751	2.800580	3.229042	3.856136	4.728250	4.234355	4.559562	3.870217	2.489114	2.982045	2.545060	2.804685	2.951774	2.272074	4.733334	3.695867	3.944394	2.691347	2.922206	2.774225	3.763383	2.470557	2.670339	3.142952	4.092113	3.349957	2.828144	2.609274	3.020278	2.584670	3.794544	2.460296	5.177389	2.314289	4.570934	3.923695	3.817413	3.267242	2.826269	3.558613	3.122019	3.469026	2.675045	4.111138	3.455895	3.196370	3.242939	2.999522	2.471145	3.453012	4.385883	2.876968	2.413970	2.816506	3.624715	3.380519	3.292433	3.811287	4.335899	4.236520	3.553264	2.596707	2.453471	3.138650	3.826477	3.795094	3.631697	3.565305	2.581267	4.170279	4.168571	3.044226	3.782988	3.523877	2.705265	3.969695	3.675063	2.461348	3.617451	2.755189	2.656865	2.411620	4.246462	2.362294	4.134983	4.143508	3.185712	3.765758	4.273862	3.083897	3.854525	1
100671	129	139	4/26/2012	4/27/2011	1	365	23.1	87	86	15	1925	Female	1500	PD	2.844229	3.121658	3.061716	3.887544	2.258637	3.030883	2.723291	3.029100	3.941273	3.042772	3.137607	2.849972	2.545307	2.877717	3.694667	4.418909	3.686967	2.792602	3.415924	3.927504	3.747800	4.016653	4.063881	3.314920	4.814726	3.612084	5.110504	3.417306	2.692230	2.817367	3.692371	4.370393	4.635746	2.358886	3.740078	3.228554	2.757092	2.735998	3.916564	3.195401	2.854427	3.456138	4.162146	3.896917	4.600522	4.654306	3.867497	3.919026	3.786475	4.486085	5.176190	5.153323	3.512964	2.975432	3.061867	3.525058	3.042890	2.991713	3.307196	2.773933	4.780288	2.906335	3.374547	3.761838	2.424555	3.852022	3.437988	3.421159	2.532372	2.951386	3.153541	2.565730	2.323665	2.769747	2.496930	3.099612	2.784689	3.123656	3.231036	3.016824	3.862674	3.333024	3.268063	3.067220	3.603285	3.247654	3.363085	3.129915	4.459709	3.694675	3.758866	3.038183	3.063371	2.693815	2.431846	2.489114	2.737272	2.744058	3.305717	3.498572	3.068037	3.316913	3.277724	3.366049	3.942147	3.946722	3.197859	3.851001	3.270562	2.976350	2.879383	3.725013	3.888112	2.704494	3.392943	3.512338	4.713344	3.246892	3.666359	4.607410	3.407968	4.077971	4.582138	3.950618	3.153571	3.525136	3.836470	2.479431	3.284431	3.085076	3.395938	4.556003	2.485295	4.184007	3.321950	2.815246	2.917190	3.745106	3.529174	2.527501	3.983698	4.429471	2.246006	4.127992	3.089658	3.422245	3.487138	2.936765	3.224921	3.661567	3.344746	3.896074	3.807102	3.064907	3.117172	3.759683	3.363837	3.960190	3.020154	2.894870	3.516218	3.326459	3.273395	2.789016	2.661245	2.645226	3.252295	3.255490	3.646227	3.229554	3.619479	2.367170	3.979976	2.414806	2.430720	4.551380	2.983130	3.303801	3.324817	4.053178	2.918816	4.396822	2.258398	2.573684	3.678008	4.050608	2.481443	3.918890	2.981003	2.700098	4.138543	3.981977	3.001344	4.045597	3.228041	4.181320	3.880808	3.432424	2.925673	2.681964	2.604658	3.698370	2.735679	2.991049	3.677999	3.798671	2.648555	4.104699	4.379746	2.835246	3.271307	3.869982	2.821579	3.183583	4.717526	3.363123	2.339849	3.998756	2.464341	4.971257	4.160954	3.459860	3.638449	4.025662	3.138271	3.435590	3.234391	4.327841	4.316886	4.177395	4.135835	3.261976	3.516707	3.263044	3.325864	2.821710	3.058426	3.434633	4.791002	3.066587	2.374932	4.061694	4.649535	3.733839	2.678882	3.250347	3.506519	2.677698	2.812245	2.494015	3.997565	3.776200	3.752701	4.589961	2.549249	2.463594	3.031812	3.523356	2.663795	4.285238	3.260429	3.079507	3.240799	2.475235	3.364945	4.096371	4.272837	2.775465	3.551712	2.580469	3.010130	3.159718	4.610446	4.336552	3.483986	2.365301	3.587520	4.302974	2.798996	3.710955	1.918030	2.838345	2.562531	4.090484	3.274135	3.189603	3.629899	3.025101	3.181986	3.550155	2.403292	2.974281	4.309602	2.548144	2.660865	2.012837	4.535795	3.449092	4.082103	3.377270	3.673445	3.043755	4.232234	4.684697	2.408749	3.294003	2.952647	2.352568	3.677981	3.067294	2.614581	3.879079	3.641008	2.878579	3.035390	2.901731	3.526171	2.299943	2.203033	3.405005	2.813581	3.981447	2.678154	2.456214	2.772542	2.791059	2.339054	3.337140	2.522966	3.147491	3.005995	2.882297	5.044982	4.803942	2.912063	2.897902	3.621353	2.852846	4.688221	3.667910	3.931229	2.831870	3.927052	2.601082	3.900438	3.844471	3.033062	2.762529	3.106225	4.125631	3.073205	2.540455	4.860364	2.855459	2.792392	3.348675	2.848066	3.225542	3.146531	3.207554	2.837652	3.150572	3.760649	2.829561	2.393575	2.855156	3.532525	1.962369	3.010045	3.975372	2.858597	2.784689	3.395519	3.710684	3.962137	3.099577	2.370513	2.924279	4.246688	3.994717	3.855979	3.490983	3.624612	2.319938	2.598353	4.335350	3.562626	3.290057	2.748963	4.135524	2.476542	2.399674	3.999865	4.100725	2.499824	4.101052	4.465780	3.683506	2.219060	3.464817	2.773274	2.977220	3.110859	3.034348	3.633125	2.509068	3.054958	3.003461	3.222795	2.303412	4.133683	2.513883	3.437782	3.782573	2.509337	3.319085	2.769599	3.364119	3.151584	2.150142	3.108700	2.774882	4.090255	4.060415	4.479607	3.693278	2.648458	3.528055	3.953388	2.830589	3.738035	3.603101	3.236814	2.853150	3.042260	2.783403	2.850279	2.328380	3.057780	2.279439	3.183697	3.832841	4.446832	3.066848	4.645026	3.070961	3.983982	3.206421	3.052732	4.489800	4.357376	3.304383	4.399262	3.506586	3.743118	2.572523	2.823474	3.852212	2.588832	3.113141	2.927165	3.449972	3.044148	3.475918	2.374382	3.066363	2.625827	2.871515	2.358506	3.039057	2.654754	2.675412	2.900913	3.974857	3.926553	3.879337	2.745777	3.106735	2.921166	3.235705	3.000087	3.567756	2.926497	2.554610	3.756636	3.080338	2.331630	3.222196	3.016992	3.211120	2.846461	2.889246	2.618571	2.513750	3.231954	2.672283	4.133504	2.218536	2.611192	3.151217	2.868233	2.428783	3.522105	4.005026	4.121205	3.436942	3.496030	3.949331	2.137671	3.119915	3.074743	3.561340	3.819800	4.302249	3.179724	2.812312	4.148461	3.764027	3.532155	2.787390	2.649530	2.976533	3.266796	3.881949	3.201424	2.570660	2.315341	3.495655	3.051384	3.498435	4.666845	2.716337	2.509337	3.296534	2.837273	2.808751	2.961801	4.556463	2.497897	2.634175	3.421374	3.534039	3.373739	2.096562	2.813381	4.741704	2.751510	4.186917	2.842172	3.336159	3.241297	4.609994	2.636087	3.425306	3.445012	3.309715	3.870064	3.743377	2.716754	2.493876	2.964542	2.638190	2.535168	3.771043	3.082175	3.770543	3.354473	1.951337	2.155336	3.297257	3.419510	3.792076	3.713314	2.617943	2.164353	3.306489	3.744582	3.822756	4.426695	4.521712	2.489114	4.522148	3.789954	3.182985	3.907352	3.140225	3.030316	3.610117	2.645717	4.194314	2.960138	3.507829	3.345922	3.075839	2.586024	3.242268	4.466245	2.408070	2.703807	2.481156	2.639984	3.943059	3.546296	2.930134	3.039731	3.784639	2.319522	2.826852	4.414836	3.345040	3.241820	3.099059	2.936966	3.822253	4.083420	4.070555	3.078203	2.734640	2.957032	2.790144	3.261049	2.627775	3.132548	2.826658	3.057476	3.465829	3.000478	3.271818	3.014647	4.399584	4.582434	3.031287	3.115577	3.569924	4.263139	3.219846	3.318356	3.599501	4.294654	3.520628	4.599842	4.015883	3.394609	3.165066	2.292920	4.007304	3.989058	2.649432	3.861260	3.022964	4.266584	3.305867	3.055684	2.594834	2.314920	3.320686	3.575604	3.524162	2.944137	2.668945	3.484926	2.901404	3.592154	3.107956	2.906227	4.145125	2.951483	2.823735	3.663079	4.211008	2.651084	2.874656	2.909235	3.037745	2.927883	2.751664	4.130803	3.071772	2.174932	3.422508	4.040950	4.588181	4.054961	3.479114	3.918413	2.861056	3.300530	2.856850	3.116973	3.632619	3.255272	3.100818	2.981003	4.293928	2.218273	4.081768	2.807603	3.063033	2.135769	3.357058	3.026737	3.556049	3.396182	3.301681	4.243829	2.615529	4.171317	4.915594	2.736874	4.129206	3.488156	3.277036	3.584862	2.845160	3.620563	3.085326	2.297979	2.719580	5.118152	2.622835	2.940616	3.403241	2.943692	3.173594	4.320128	3.785750	3.255104	3.591098	3.064608	3.621166	4.392644	4.021561	3.056142	2.804616	3.336320	2.580697	2.693639	2.306639	3.580765	2.918554	3.884563	4.401126	3.671737	3.213597	4.460010	3.709948	3.201233	3.236235	3.969467	3.400072	3.152227	2.337659	3.902351	3.406370	2.267406	3.861230	3.063033	2.776774	2.871865	2.573336	3.365357	3.148140	2.675503	3.240624	2.387568	2.975386	3.048791	3.256549	3.462533	3.779762	3.123819	4.477386	4.346181	3.381620	3.700868	4.222355	3.043794	3.185004	2.567262	3.100784	3.158694	2.976762	3.206259	2.914396	3.880682	4.313639	3.295391	3.602440	2.512818	3.124830	3.162505	2.796644	3.229426	2.519040	2.634175	4.741660	3.427892	2.820792	4.466442	3.856608	3.897165	3.621239	2.630936	4.325805	3.200303	2.869642	3.847357	4.332143	3.260215	2.424718	2.786183	3.418135	4.042245	2.877198	2.788875	3.602873	3.345256	2.870053	3.775778	4.002516	3.813261	1.993436	3.699768	2.904770	2.926445	3.960047	3.586711	2.418964	3.089623	4.520169	3.488734	3.792728	2.820858	4.861601	3.365806	3.506234	4.430693	4.005494	3.211734	2.777354	2.948706	2.307282	4.009948	4.292517	4.214221	4.029688	2.722881	3.283753	3.565718	2.468790	2.938119	3.262309	4.345682	3.837891	2.829304	2.687707	3.588944	3.480539	3.979771	3.170965	3.211414	4.104364	2.674769	3.893012	4.213621	3.213226	3.345080	3.585416	3.108328	2.739810	2.706035	3.119388	2.974696	4.080569	3.657400	3.360574	4.362390	3.401125	2.807400	3.203441	3.878464	4.676714	3.139281	4.538699	3.356332	2.728759	3.412158	2.513750	3.675192	2.826593	2.785970	4.674288	3.583947	3.887358	2.666424	2.842484	3.685034	3.561817	2.712566	2.860098	3.181071	4.042906	3.433738	2.824516	3.032296	3.043559	2.615950	3.551670	2.459091	5.084829	2.248709	4.680967	3.805242	4.000126	3.314183	2.762604	3.453594	3.024198	3.338576	2.662947	3.775108	3.040919	2.827498	3.156701	3.664266	2.470851	3.396513	4.204641	2.986593	2.494155	2.576687	3.635403	3.350539	3.444263	3.832835	4.249017	4.297690	3.704811	2.816241	2.390759	3.048286	3.656664	3.781080	3.539490	3.644439	2.643847	3.880734	4.185267	3.089340	3.708905	3.568554	2.866642	3.763053	3.691833	2.565494	4.032401	2.832892	2.528274	2.368844	4.418492	2.712060	4.232073	3.826133	3.282395	4.056558	4.329113	3.102056	3.735775	1
101690	140	139	9/14/2016	10/5/2011	0	1806	59.2	68	63	8	1948	Male	1964	PD	2.871164	3.251663	3.144854	3.934251	2.265996	2.670895	2.631647	2.833147	3.824523	2.521138	3.637810	2.780101	2.660486	2.746790	3.575465	4.606060	3.486388	2.865045	3.406046	3.769400	3.474537	4.088721	4.109784	3.386838	5.080719	3.608932	5.068577	3.865856	2.686368	2.884115	3.481686	4.383086	4.156364	2.093422	3.706453	2.743980	2.824841	2.697142	4.164317	3.156004	2.840106	3.380392	3.985952	3.813147	3.758503	4.789092	4.161149	4.267059	3.863132	4.335811	5.214506	5.093184	3.431106	3.063596	2.726483	3.578330	2.876333	3.180212	3.254959	2.836641	4.963150	3.326827	3.543596	4.047349	2.477844	3.697282	2.407391	3.592421	2.570776	3.113910	3.585156	2.516271	2.527114	3.085362	2.779452	2.869232	2.990871	2.989939	3.106667	3.096284	3.692459	3.412813	3.212161	3.144916	3.610543	2.848989	3.471614	3.175541	4.677889	3.751402	3.570298	3.430623	3.232996	2.842796	3.023623	2.821120	2.795463	2.666986	3.380591	3.558709	2.953760	3.434968	3.151125	3.648467	3.704082	4.139760	3.135927	3.841585	3.379922	2.898396	2.667640	3.851430	4.135517	2.826787	3.280260	3.790194	4.871370	3.264676	3.912801	4.800869	3.254572	3.847949	4.433703	4.058506	2.907680	3.260596	3.590061	2.388634	2.975340	3.852529	2.911690	4.600062	2.346157	3.740228	3.493486	2.252368	3.108328	3.349433	3.520156	2.523096	3.944936	4.292278	2.332438	3.828731	3.249247	3.326745	3.431444	2.910090	3.750045	3.522757	3.413384	3.683182	3.889655	3.171522	3.040879	3.835120	3.414890	4.185389	2.347135	2.854367	3.074194	3.324241	3.454951	2.623042	2.693727	2.747800	3.322550	3.240275	3.769680	3.222378	3.565352	2.313867	3.986485	2.439175	2.381115	4.963861	2.950900	3.151063	2.946894	4.000577	2.891314	4.170526	2.290702	2.684037	3.559512	4.521873	2.613736	4.039386	2.898835	2.699664	4.201834	4.044798	2.751125	4.108680	3.354800	3.987090	4.057248	3.408732	2.866996	2.630733	2.725094	3.820865	2.663795	2.830011	3.473020	3.587890	2.562174	3.983247	4.235170	2.796297	3.252270	3.623849	2.841547	3.168821	4.098436	3.368361	2.305136	4.082135	2.560146	4.951277	3.948066	3.293473	3.857953	4.160622	2.902329	3.336500	3.396949	4.304742	4.303358	4.211014	4.125582	3.065281	3.459573	3.195844	3.215056	2.703291	3.033102	3.348149	4.748500	2.931407	2.480151	3.533314	3.957665	3.785166	2.729084	3.179437	3.619250	2.586475	2.791199	2.617629	3.915563	3.825192	3.804017	4.407041	2.698883	2.406881	3.158543	3.306768	2.692847	4.287208	3.366255	3.000260	3.148140	2.552547	3.470793	3.908705	3.963486	2.691524	3.761161	2.673482	3.162773	3.398339	4.685892	4.392116	3.990308	2.323458	3.808008	4.324023	2.655619	3.621685	2.055760	2.831550	2.642069	4.070861	3.197143	3.120673	3.631007	2.854063	2.991802	3.444482	2.453012	2.996555	4.578144	2.980185	2.789510	2.065206	4.302201	3.373537	3.980590	3.578410	3.279142	3.301008	4.413826	4.738506	2.445448	3.435191	3.075218	2.270213	3.356924	2.989628	2.415641	3.901469	3.584908	2.861355	2.864630	3.065057	3.569526	2.389166	2.223756	3.283437	2.483587	4.017655	2.739730	2.448088	2.571359	2.715335	2.331630	3.096354	2.928191	2.849726	3.182329	2.746089	5.103294	4.869477	2.940915	2.880185	3.643985	2.845904	4.884236	3.847060	3.044265	2.939918	3.784453	3.035790	4.377639	3.705889	2.795741	2.683857	2.731024	4.148041	3.093387	2.705949	4.840756	3.052656	2.948071	3.192233	2.864036	2.922154	3.312410	3.137987	2.814780	3.221701	3.935316	2.886604	2.510277	2.891816	3.451955	1.979093	3.075729	3.859691	3.138429	2.770705	3.629002	3.607637	4.153385	3.074524	2.408918	2.883548	4.049962	4.041278	3.702723	3.324324	3.524824	2.332842	2.491502	4.489062	3.400175	3.515317	2.800305	3.989619	2.570893	2.488692	4.063652	4.448222	2.398287	3.919726	4.658236	3.461949	2.345570	3.460853	2.737113	2.636388	3.340722	3.090928	3.936760	2.642267	3.088526	2.463594	3.007748	2.322839	3.907857	2.521792	3.240075	3.428669	2.433450	3.470513	2.647969	3.440547	3.287443	2.144574	3.357210	2.694868	4.011676	3.953068	4.330511	3.612413	2.656098	3.807792	3.414255	2.844415	3.774517	3.804078	3.166430	2.757168	2.916349	2.804480	2.332236	2.302547	3.345668	2.969788	3.093597	4.153025	4.595982	2.626853	4.845984	2.941958	3.776338	3.116276	2.917243	4.728206	4.266958	3.345374	4.885228	3.748188	3.838931	2.659631	2.411283	3.971865	2.603686	2.947630	2.984752	3.591654	3.053616	3.292234	2.353532	3.161937	2.659155	2.854610	2.466868	3.648692	2.621488	2.714916	3.100612	3.938750	4.153425	4.141585	3.203686	3.311521	3.072911	3.394837	2.911477	3.507221	2.721068	2.481156	3.087817	3.599140	2.475526	3.298154	3.035990	3.206961	2.847573	2.996687	2.664360	2.604766	3.487294	2.582745	4.357943	2.295787	2.790496	3.062206	2.740284	2.342620	3.647451	4.069254	4.015540	3.384371	3.478292	3.858970	2.282622	3.017326	2.971137	3.256742	4.178617	4.462664	3.237041	3.007150	4.338646	3.768764	3.435111	2.842796	2.758761	3.042969	3.080374	4.077382	3.272723	2.571010	2.530456	3.695972	3.041037	3.418898	4.756171	2.751741	2.586137	3.144543	2.528274	2.700011	2.828531	4.695771	2.636187	2.666892	3.340464	3.362652	3.360745	2.049218	2.909930	4.929021	2.655427	4.020776	2.819149	3.365076	3.200932	4.486974	2.719414	3.377270	3.546000	3.044304	4.098270	4.358833	2.828402	2.501059	2.740678	2.626648	2.590396	3.770329	3.039097	4.026693	3.480711	2.054996	2.228913	3.306554	2.929879	3.754616	3.410575	2.587150	2.305136	3.484385	3.947149	3.669233	4.396991	4.661453	2.498999	4.380294	3.756864	3.051461	4.011147	2.844166	2.844912	3.754096	2.442636	4.125709	3.148603	4.022028	2.678791	2.918973	2.483872	3.124178	4.369019	2.430559	2.933133	2.428135	2.639586	4.204435	3.459739	3.094226	3.604701	3.665506	2.408410	2.878637	4.212097	3.156216	3.089304	2.256718	2.885361	3.527797	4.207209	3.932773	2.973082	2.753430	2.803730	2.708761	2.960233	2.778730	3.307881	2.708846	3.052502	3.554186	4.038394	3.240400	3.005995	4.347002	4.643579	3.230423	3.044853	3.431557	4.562242	3.474901	3.215796	3.893790	4.454528	3.365582	4.600471	3.799630	3.738574	3.012922	2.383277	3.428281	4.204923	2.864689	3.657075	3.128335	4.174426	3.387941	3.000608	2.687529	2.396896	3.293694	3.403755	3.603815	2.918030	2.735679	3.416774	2.966986	3.537668	3.297848	2.805433	4.326274	2.945911	2.898670	3.520090	4.474034	2.579212	2.854185	2.942603	3.048131	2.773347	2.626238	3.904981	2.995942	2.180699	3.364907	4.054291	4.103547	4.386654	3.598188	3.969015	2.871398	3.284949	2.779524	3.178718	3.609392	2.574610	3.332337	2.965860	4.279840	2.288025	3.684271	2.778658	3.024486	2.185825	3.568378	3.095065	3.613123	3.436163	3.375719	4.170227	2.557026	3.441617	4.105721	2.744684	4.157496	3.723135	3.136689	3.529802	2.848066	3.479446	2.830011	2.419129	2.539829	4.052998	2.702689	3.117570	3.256862	2.856124	3.708106	4.191557	3.792125	3.000000	3.639357	3.042615	3.476904	4.369774	3.717238	2.877544	2.791971	3.456290	2.714832	2.853698	3.213597	3.467119	2.842796	3.435908	4.433418	3.387941	3.096354	4.640129	3.718676	2.865222	3.322343	3.819939	3.211788	3.366460	2.437275	3.807948	3.318210	2.710456	3.827550	2.908967	2.835310	2.794976	2.508664	3.557880	3.105101	2.547405	2.678973	2.356599	2.966470	2.456821	3.093877	3.575892	3.496071	3.011401	4.381176	4.243251	3.632842	3.655993	3.805929	3.130977	3.443263	2.387746	2.963316	3.102502	2.985067	3.024609	3.061716	4.046437	4.492122	3.251273	3.652343	2.582745	3.059488	3.027553	2.647676	2.902003	2.436481	2.530840	4.629696	3.512377	3.542527	4.675950	3.600472	3.768372	3.535497	2.655619	4.145796	3.409747	3.066810	3.786915	4.527924	3.082857	2.458033	3.057628	3.429817	4.301037	2.937668	2.741860	3.794662	3.244104	2.745699	3.882889	4.212014	3.633196	2.097951	3.822312	3.001734	2.967361	4.152328	3.371696	2.191171	3.251541	4.668666	3.398253	3.775742	2.746945	4.556715	3.591932	3.553082	4.491549	3.778679	3.109579	2.739493	3.460642	2.598900	3.818958	3.720754	4.311173	3.851387	2.680517	3.097535	3.389609	2.239800	2.909556	3.453012	4.173591	3.687761	2.793301	2.589167	3.633155	3.486601	4.042808	3.402313	2.915189	3.912525	2.744528	3.819583	4.368963	3.120376	3.361010	3.040642	3.046339	2.714581	2.674034	3.376650	2.714581	3.936473	3.496071	3.397853	4.511965	3.351062	3.018368	3.187887	3.806445	4.923693	3.268812	4.449650	3.268742	2.431203	3.148479	2.576917	2.854488	2.960376	2.301030	4.728374	3.546456	3.911360	2.429591	2.747334	2.898176	3.818773	2.649237	2.698622	3.036629	3.949507	3.357344	2.849788	2.601951	3.554586	2.785116	2.965108	2.475381	5.002537	2.333447	4.615734	4.038529	3.857206	3.213916	2.899930	3.637139	2.973636	3.494530	2.722469	3.848060	2.817632	3.030842	3.233402	2.895533	2.437275	3.468746	4.166874	2.733037	2.394802	2.665769	3.516324	3.226858	3.255031	3.666902	4.179443	4.278802	3.511616	2.920071	2.432969	2.987979	3.597531	3.849548	3.739754	3.373041	2.534153	4.060052	4.177095	2.862131	3.954768	3.783896	2.767304	3.837380	3.570858	2.525692	3.818483	2.819873	2.592510	2.802500	4.164757	2.496930	4.089043	3.829715	3.069224	3.841997	4.397365	3.058957	3.948853	0
101943	144	143	2/11/2015	12/8/2010	0	1526	50.0	62	58	4	1952	Female	0	PD	2.711723	3.366180	3.169557	3.804242	2.347915	2.627058	2.692935	2.806655	3.650939	2.473779	3.150941	3.204988	2.611086	2.643749	3.332398	4.626629	3.399933	2.785614	3.454464	3.820694	3.589804	3.920801	4.123064	3.323087	4.943632	3.614802	5.170493	3.866075	2.757927	2.931661	4.215957	4.377497	4.075682	2.224015	3.608258	2.712986	2.841610	2.663889	4.045362	3.189518	2.930694	3.465070	4.240993	3.922476	3.874551	4.751276	3.938985	3.870615	3.869513	4.495665	5.301210	5.191139	3.228144	2.992288	2.688687	3.497814	2.812713	3.098921	3.169880	2.866169	4.919799	2.896692	3.458169	3.882519	2.573104	3.665722	2.554126	3.621103	2.565376	3.220866	3.193347	2.489677	2.478278	2.572872	2.917820	2.979958	3.346588	3.077586	2.944038	3.186080	3.853589	3.390688	3.116674	3.087178	3.657906	2.943346	3.396844	3.019988	4.480204	3.594459	3.544651	3.323623	2.867173	2.859319	2.636087	2.489114	2.771661	2.523877	3.346177	3.384658	3.049334	3.474508	3.120541	3.902585	3.727435	3.815332	3.532130	3.879738	3.311839	3.106327	2.689753	3.862573	4.421795	2.784974	3.219637	3.650463	4.886739	3.331933	3.858411	4.757841	3.101575	4.080616	4.443640	4.021520	3.013511	3.684271	3.690816	2.356026	3.109815	3.363875	2.954821	4.300702	2.260310	3.429155	3.369809	2.615003	3.025674	3.428200	3.522874	2.445604	3.802144	4.110277	2.538699	4.043449	3.181443	3.361180	3.469144	2.894150	3.510679	3.670682	3.350287	3.570263	3.788190	3.118926	3.097951	3.966024	3.453731	4.083685	2.374015	2.859319	3.604528	3.428653	3.346118	2.503655	2.649432	2.727297	3.264700	3.213066	3.799154	3.178401	3.398027	2.282169	3.932149	2.498311	2.374748	4.930010	2.798927	2.949488	2.897352	3.911147	2.829947	4.129448	2.301898	2.981683	3.534280	4.534340	2.582518	4.110687	2.995679	3.019615	4.233897	4.074901	3.009578	4.111262	3.404492	4.141243	3.787361	3.476382	2.979958	2.569725	2.775974	3.848318	2.783189	3.009876	3.399829	3.445137	2.659726	3.924109	4.750628	2.787177	3.188563	3.679646	2.830139	3.117901	4.030345	3.322012	2.468200	4.071396	2.524656	4.963452	3.982610	3.307753	3.571953	3.515225	2.907250	2.598243	3.234618	4.188284	3.616181	4.178991	4.141917	3.055417	3.517037	3.145756	3.310608	2.676968	2.846585	3.409291	4.906396	2.864808	2.624282	3.595739	4.192765	3.501183	2.685383	3.909021	3.544515	2.561101	2.789369	2.569140	4.283936	3.798236	3.941571	4.411576	2.626956	2.461649	3.155457	3.216957	2.588048	4.470400	3.269676	2.934751	3.064608	2.524136	3.320562	3.837948	3.900531	2.681603	3.607401	2.379306	2.886885	3.432937	4.742407	4.384240	3.942920	2.541953	3.671488	4.198368	2.813981	3.847974	2.101747	2.759970	2.504471	4.215048	3.215320	3.128528	3.625601	2.973035	3.320167	3.448552	2.442480	2.996380	4.546317	2.589167	2.836577	2.162863	4.458420	3.376504	3.769333	3.460206	3.350248	3.044108	4.311383	4.878965	2.310481	3.430188	2.893873	2.255272	3.387283	3.392697	2.440909	3.693876	3.810125	2.978272	3.008515	2.769377	3.409595	2.322426	2.219846	3.165333	2.455910	3.207338	2.659726	2.397592	2.974880	2.960994	2.300161	3.105408	2.528917	2.785259	3.173274	2.694693	5.124318	4.826887	3.099197	2.865933	3.588988	2.830845	4.787311	3.759849	3.828215	3.025634	3.831159	2.596377	3.812967	3.744418	2.917978	2.579669	2.850830	4.084826	3.054843	2.594945	4.824316	3.018950	2.877717	3.216957	2.779091	2.814114	3.355222	3.071366	2.775902	3.319585	4.025560	2.837715	2.389343	2.807941	3.086609	1.909021	3.107108	3.738852	2.924021	2.660581	3.557098	3.788861	4.077847	3.003977	2.426349	2.763353	4.080904	3.969728	3.711967	3.499165	3.687315	2.297323	2.494433	4.478435	3.535522	3.387888	3.198300	4.015511	2.563481	2.465383	4.066561	4.335348	2.305566	3.924062	4.706188	4.155907	2.388634	3.419361	2.746401	2.806112	3.224507	3.021727	3.694131	2.590396	2.923607	2.946010	3.117205	2.235781	4.288759	2.516535	3.318481	3.679346	2.422426	3.623229	2.539327	3.352742	4.349668	2.129045	3.306146	2.661150	5.011144	3.949731	4.448009	3.540317	2.662475	3.687627	3.807893	2.768564	3.713281	3.710270	3.213757	2.637089	2.813114	2.705351	2.286905	2.383636	3.911562	2.781612	3.113910	3.866884	4.488672	2.592066	4.474428	3.054996	4.028099	3.193375	2.895367	4.702224	4.343229	3.272978	4.596057	3.379197	3.787744	2.640978	2.428135	3.962497	2.644832	3.040840	3.006509	3.415741	3.053040	3.521635	2.344981	3.065654	2.681874	2.683857	2.429591	2.992421	2.816374	2.743118	3.022676	3.993683	4.071307	3.864469	2.787106	3.218929	3.002080	3.346470	3.057095	3.365488	2.736636	2.700963	3.026615	3.689584	2.533772	3.261001	3.212534	3.243038	2.744762	2.941859	2.610873	2.696269	3.249541	2.700357	4.152866	2.669875	2.611936	3.023088	2.774663	2.387746	3.369587	4.092987	3.980571	3.509915	3.408783	3.816699	2.130655	3.180183	2.960566	3.469115	3.963013	4.299895	3.200331	2.771146	4.122560	3.782207	3.322984	2.786325	2.626340	3.006466	2.913708	3.776047	3.203060	2.575419	2.566320	3.632832	3.047820	3.477888	4.746868	2.640978	2.610341	3.107719	2.645913	2.684756	2.796782	4.678061	2.490239	2.673205	3.364307	3.371437	3.273302	3.040088	3.207823	4.759091	3.010257	4.257712	2.857694	3.203441	3.162744	4.326063	2.730136	3.419162	3.484229	3.168792	3.475540	4.013469	2.866405	2.856789	2.779524	2.723948	2.619928	3.751379	2.995898	3.964919	3.347486	2.320977	2.368659	3.309971	3.659098	3.748963	3.551865	2.644143	2.376942	3.479172	3.842965	3.746276	4.407399	4.564066	2.463893	4.337265	3.699170	3.090928	3.764027	2.959852	2.812312	3.762086	2.522575	4.171981	2.837652	3.754371	2.778224	2.922414	2.798789	3.150787	4.300063	2.422754	2.613842	2.622421	2.592288	4.021962	3.422787	2.772468	2.895423	3.589425	2.386499	2.821055	4.141544	3.228169	3.113576	2.283527	2.919914	3.437132	4.187109	3.948990	2.930083	2.785116	2.789299	2.872040	2.496099	2.604982	2.869994	2.845656	3.001084	3.481098	3.035990	3.037347	3.169027	4.266321	4.598392	3.114511	3.125611	3.482001	4.705682	3.475860	3.409696	3.558252	4.419928	3.440468	4.360862	3.733358	3.577549	3.022346	2.379306	3.371696	3.956072	2.625004	3.525213	3.145973	4.097566	3.377598	3.095692	2.570543	2.357554	3.289901	3.228015	3.270749	2.891370	2.698709	3.497676	2.825361	3.532002	3.366964	2.743353	4.272939	2.948853	2.926857	3.747629	4.285850	2.598243	2.861415	2.834866	3.086395	2.778079	2.641077	4.068627	3.082642	2.260310	3.388687	4.166679	4.291786	4.178531	3.523343	3.807839	2.946501	3.212933	2.759366	3.072948	3.411333	2.829754	3.218010	3.649481	3.872820	2.314499	3.852212	2.765296	2.980821	2.155943	3.620979	3.049993	3.587823	3.314183	3.386713	4.099242	2.591955	3.505869	4.226303	2.585799	3.617504	3.408969	3.276025	3.434345	2.873088	3.308458	2.832126	2.350442	2.811441	4.181366	2.672190	2.920123	3.176381	2.717254	3.346881	4.240764	3.762634	3.864766	3.623725	3.034107	3.471277	4.230474	3.738091	2.918240	2.890812	3.367431	2.799409	2.632356	2.640481	3.359399	2.974880	3.247900	4.279316	3.566508	2.907304	4.603585	3.748397	3.049954	3.307218	3.761928	3.223937	3.248733	2.450249	3.787715	3.689513	2.416641	3.688028	2.945025	2.814381	2.709609	2.441538	3.513737	3.055684	2.598900	2.948706	2.307710	2.853698	2.985202	3.023828	3.548635	3.598232	3.032659	4.321358	4.140341	3.474522	3.357744	3.813894	3.038143	3.207957	2.625004	2.996249	3.090329	2.886039	3.034749	3.325125	4.031631	4.489079	3.205908	3.745473	2.483872	3.089552	3.106395	2.924072	3.227552	2.392873	2.517460	4.668438	3.395064	2.584331	4.603495	3.628604	3.697639	3.664285	2.639885	4.302004	3.344648	2.971786	3.670431	4.592497	3.033464	2.430398	3.106837	3.441287	4.193225	2.934499	2.819149	3.681522	3.144699	2.984212	3.281283	3.888342	3.564382	2.127105	3.588921	3.046690	2.742882	4.347221	3.455500	2.356790	3.191730	4.296086	3.299529	3.815538	2.796436	4.889902	3.145662	3.692300	4.378192	3.714003	3.047781	2.713910	3.003245	2.928652	3.872506	4.292969	4.124807	3.891013	2.938720	3.037546	3.401142	2.185825	2.901349	3.395728	4.265339	4.029071	4.541066	2.652730	3.550852	3.324303	4.134499	3.424555	2.888292	3.760106	2.668945	3.830832	4.258113	3.113643	3.433290	2.962085	2.929725	2.766338	2.730298	3.284701	2.805025	3.931829	3.472464	3.490885	4.321940	3.384980	2.861355	3.323768	3.832758	4.792141	3.322715	4.429526	3.228657	2.738305	3.153571	2.620968	2.941511	3.300921	2.310268	4.838538	3.598101	3.964943	2.575188	2.804208	3.041037	3.723489	2.595606	2.655331	3.057019	4.053739	3.363386	2.811642	2.678791	3.050264	2.693815	3.506397	2.477411	5.028214	2.360215	4.541613	3.910832	3.764945	3.249834	2.868233	3.515980	3.041116	3.372765	2.772322	3.991572	3.292433	2.733358	3.020361	2.902275	2.446382	3.396496	4.306191	2.960804	2.356408	2.552303	3.231979	3.131169	3.301399	3.585957	4.063937	4.225351	3.486785	2.760649	2.561101	2.904716	3.642385	3.753307	3.637640	3.368807	2.468790	3.978436	4.150400	2.765817	3.978838	3.687359	2.781612	3.863692	3.643453	2.589056	3.869795	2.858958	2.569608	2.447623	4.093040	2.504063	4.010177	4.012614	3.089304	3.880934	4.177802	3.035029	3.851845	0

survival.upenn$YearsVisitToSample = survival.upenn$DaysVisitToSample/365

# Create survival object
survive_object = Surv(survival.upenn$YearsVisitToSample, survival.upenn$Event)

# Equally binning patients into quartiles based on their blood MIA concentration
# Convert the MIA factor variables into factor variables
survival.upenn$IGFBP.2_Factor <- with(survival.upenn, factor(
                            findInterval( IGFBP.2, c(-Inf,
                               quantile(IGFBP.2, probs=c(0.25,0.5,0.75)), Inf)), 
                            labels=c("First Quartile","Second Quartile","Third Quartile","Fourth Quartile")
      ))
survival.upenn$IGFBP.2_Factor = as.factor(survival.upenn$IGFBP.2_Factor)

IGFBP.2_Factor = coxph(survive_object ~ AgeAtSample + Sex + DieseaseDuration + IGFBP.2_Factor,data = survival.upenn)

# Take a look at the summary of Cox model
summary(IGFBP.2_Factor)

## Call:
## coxph(formula = survive_object ~ AgeAtSample + Sex + DieseaseDuration + 
##     IGFBP.2_Factor, data = survival.upenn)
## 
##   n= 71, number of events= 21 
## 
##                                   coef exp(coef) se(coef)     z Pr(>|z|)   
## AgeAtSample                   0.109164  1.115345 0.039163 2.787  0.00531 **
## SexMale                       1.329770  3.780176 0.563598 2.359  0.01830 * 
## DieseaseDuration              0.017114  1.017261 0.006306 2.714  0.00665 **
## IGFBP.2_FactorSecond Quartile 1.103468  3.014603 0.931204 1.185  0.23602   
## IGFBP.2_FactorThird Quartile  1.391837  4.022231 0.857409 1.623  0.10452   
## IGFBP.2_FactorFourth Quartile 1.991001  7.322860 0.841883 2.365  0.01803 * 
## ---
## Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
## 
##                               exp(coef) exp(-coef) lower .95 upper .95
## AgeAtSample                       1.115     0.8966    1.0329     1.204
## SexMale                           3.780     0.2645    1.2525    11.409
## DieseaseDuration                  1.017     0.9830    1.0048     1.030
## IGFBP.2_FactorSecond Quartile     3.015     0.3317    0.4859    18.701
## IGFBP.2_FactorThird Quartile      4.022     0.2486    0.7493    21.592
## IGFBP.2_FactorFourth Quartile     7.323     0.1366    1.4063    38.132
## 
## Concordance= 0.8  (se = 0.041 )
## Likelihood ratio test= 22.16  on 6 df,   p=0.001
## Wald test            = 16.04  on 6 df,   p=0.01
## Score (logrank) test = 20.77  on 6 df,   p=0.002

coxCurve_IGFBP.2 <- ggadjustedcurves(IGFBP.2_Factor, data = survival.upenn, method = "average", variable = "IGFBP.2_Factor", legend.title = "Plasma IGFBP.2 level Quartile") + 
  labs(title = "Clinical Conversion by IGFBP.2 subgroup \n (UPenn Cohort)", x = "Time (Years)", y = "% Cognitively Normal")  + 
  theme_classic() +
  theme(legend.position = c(0.35, 0.3), legend.title = element_text(face = "bold", size = 18), legend.text = element_text(size = 18),
        title = element_text(size = 18),
        axis.title.x = element_text(size = 20, margin = margin(t = 10, r = 0, b = 0, l = 0)),
        axis.title.y = element_text(size = 20, margin = margin(t = 0, r = 12, b = 0, l = 0)),
        axis.text = element_text(size = 20, color = "black"), axis.line = element_line(size = 1), axis.ticks = element_line(size = 1))
coxCurve_IGFBP.2

fit_coxph_MIAcog.forest <- ggforest(IGFBP.2_Factor , data = survival.upenn, main = "Hazard Ratios", 
                          cpositions = c(0.02, 0.23, 0.4), fontsize = 1, refLabel = "reference", noDigits = 2)
fit_coxph_MIAcog.forest

Longitudinal Motor Function Analaysis

UPDRS III (Motor Function) ~ Age + Sex + Disease Duration

setwd('/Users/junchaoshen/UPenn BMI')
UTSW.UPDRS = read.csv('UTSW UPDRS Longitudinal Final.csv')
UTSW.UPDRS.merge = merge(UTSW.UPDRS,df, by = 'GUID',all.x = TRUE)
kable(UTSW.UPDRS.merge[1:5,], "html") %>% kable_styling("striped") %>% scroll_box(width = "100%")

GUID	YearstoVisit	AgeAtSample	AgeAtTest	DiseaseDuration	Sex	UPDRS3	LEDD	Group	Site	Age	LDOPADoseTm	MDS_UPDRS.Total.Score	Gender	PlateId	CHIP	CEBPB	NSE	PIAS4	IL.10.Ra	STAT3	IRF1	c.Jun	Mcl.1	OAS1	c.Myc	SMAD3	SMAD2	IL.23	PDGFRA	IL.12	STAT1	STAT6	LRRK2	Osteocalcin	IL.5	GPDA	IgA	LPPL	HEMK2	PDXK	TLR4	REG4	HSP.27	YKL.40	Alpha.enolase	Apo.L1	CD38	CD59	FABPL	GDF.11	BTC	HIF.1a	S100A6	SECTM1	RSPO3	PSP	Apoptosis.regulator.Bcl.W	VEGF.D	SOST	FAM3D	CSH	EFNB1	SNP25	LYPD3	NEGR1	BCL6	FSTL1	Osteopontin	Lumican	CD177	CHKB	SMOC1	protein.Z.inhibitor	FLRT2	FLRT3	ISLR2	Vitronectin	DSC2	LDLR	HXK2	HXK1	SEM5A	LTBP4	PIANP	Adrenomedullin	S100A4	RNF43	TRAIL.R4	ZNRF3	GI24	Ephrin.A2	ApoM	IFN.b	IFN10	IFNA7	EFNB2	HHLA2	IL.1.sRII	AMGO2	RXFP1	C1QR1	NRG4	H2B2E	H2A3	H31	IFN.g	IL.1F8	IL.1F6	UCRP	Ephrin.A3	X14.3.3.protein.beta.alpha	X14.3.3E	Annexin.V	Myostatin	C4b	Coagulation.Factor.XI	CTACK	Endostatin	TIMP.1	tPA	EG.VEGF	TIMP.2	TGF.b1	VEGF.sR3	C5	Apo.E	BDNF	C8	Cathepsin.G	CXCL16..soluble	FGF.10	FGF.8B	GIIE	GV	MIP.3a	SAP	SCF.sR	TIMP.3	Angiopoietin.4	Cadherin.E	GFRa.3	Ephrin.B3	GFRa.2	X6Ckine	HMG.1	OPG	b.Endorphin	Factor.I	IGFBP.3	MCP.1	MMP.9	Myeloperoxidase	PRL	VEGF	X4.1BB	X4.1BB.ligand	Angiopoietin.2	B7	CD30	CLF.1.CLC.Complex	Cystatin.C	Dtk	eIF.5	Ephrin.A4	Ephrin.A5	ERBB2	ERBB3	ERBB4	GA733.1.protein	gp130..soluble	HO.2	HPV.E7.Type.16	HPV.E7.Type18	HSP.90a.b	IL.1.R.AcP	IL.10.Rb	IL.12.Rb1	IL.13.Ra1	IL.2.sRg	Layilin	Lymphotoxin.b.R	Macrophage.mannose.receptor	M.CSF.R	MSP.R	PAFAH.beta.subunit	P.Cadherin	PKC.A	PKC.Z	Rab.GDP.dissociation.inhibitor.beta	sICAM.3	suPAR	TNF.sR.I	TrkC	BCMA	Bone.proteoglycan.II	Calpain.I	CK.MM	ERBB1	HGF	HSP.60	iC3b	IGFBP.5	IGFBP.6	MIA	NPS.PLA2	OSM	PECAM.1	Persephin	PF.4	Protein.S	TACI	TECK	Thyroxine.Binding.Globulin	TNFSF18	CNTFR.alpha	EMAP.2	EPO.R	G.CSF.R	IL.1F7	Laminin	MICA	NADPH.P450.Oxidoreductase	NANOG	NKp44	NovH	Siglec.6	Siglec.7	Sonic.Hedgehog	IgG	TSLP.R	ULBP.3	Activin.A	Apo.A.I	Azurocidin	BMP.14	C1q	C3	C3adesArg	DRR1	FGF.18	FGF.19	FGF.20	FGF9	GDF.11.8	Hemopexin	HIV.2.Rev	I.309	IGFBP.1	IL.10	IL.16	IL.17F	IL.22	Lactoferrin	LAG.1	LD78.beta	MCP.2	MMP.3	MMP.7	NAP.2	SOD	Fibrinogen	Apo.B	ACE2	Activin.RIB	ADAMTS.4	Angiopoietin.1	ART	BCAM	Cadherin.5	CD97	COMMD7	EDA	Fractalkine.CX3CL.1	HAI.1	IL.27	Kallikrein.11	Kallikrein.4	kallikrein.8	Ku70	Lipocalin.2	Met	MMP.17	OX40.Ligand	sFRP.3	SPINT2	sTie.1	Ubiquitin.1	WIF.1	AIF1	C5a	CHK1	ERK.1	Glucocorticoid.receptor	Hat1	HDAC8	Karyopherin.a2	MEK1	MOZ	PKC.D	RAC1	RAD51	TBP	Topoisomerase.I	UBC9	YES	a1.Antichymotrypsin	C7	Cardiotrophin.1	CCL28	CD22	HCC.1	IL.4	Midkine	MPIF.1	PCNA	sRANKL	PAI.1	Apo.E3	Apo.E4	Artemin	Cytochrome.c	Cytochrome.P450.3A4	DAN	ER	Factor.D	Growth.hormone.receptor	GX	IGFBP.4	IGF.I	Luteinizing.hormone	Properdin	Protein.C	PTHrP	SCGF.beta	VCAM.1	TNFSF15	ALK.1	AREG	BMP.7	CD36.ANTIGEN	contactin.1	CTGF	Desmoglein.1	EDAR	ENA.78	ESAM	Galectin.4	Gro.a	Gro.b.g	Histone.H1.2	ICOS	IL.1.sRI	IL.17.sR	IL.18.Rb	IL.1Rrp2	JAM.B	JAM.C	LSAMP	MBL	NKp30	PD.L2	PTP.1B	Siglec.9	TGF.b.R.III	TSLP	CTLA.4	a2.Antiplasmin	bFGF	Calpastatin	Ck.b.8.1	DC.SIGN	DC.SIGNR	FSH	Galectin.2	GFAP	IL.19	IL.1b	I.TAC	MIP.1a	MRC2	Myoglobin	ON	PARC	PTN	resistin	Trypsin	vWF	Fas.ligand..soluble	Flt3.ligand	Haptoglobin..Mixed.Type	IL.4.sR	NKG2D	WISP.1	BAFF	C9	Cathepsin.B	FGF.5	Galectin.3	GDF.9	IgM	IL.2	IL.13	IL.18.BPa	LBP	Coagulation.Factor.Xa	PlGF	TIG2	ULBP.1	ULBP.2	XEDAR	Aurora.kinase.A	MK01	SMAC	VEGF.C	sCD4	IL.2.sRa	TNF.sR.II	Siglec.3	ADAMTS.5	IDUA	AMPM2	amyloid.precursor.protein	ARSB	ASAHL	ATS1	ATS13	Carbonic.Anhydrase.IV	CATC	Cathepsin.A	Cathepsin.S	CD39	Coagulation.Factor.VII	C2	CRIS3	Enterokinase	WFKN1	Glutamate.carboxypeptidase	GPVI	Granulysin	HPLN1	IDE	IDS	kallikrein.12	kallikrein.13	kallikrein.5	KREM2	LKHA4	LYVE1	MATN3	MEPE	METAP1	ASAH2	Nidogen	PIGR	Protease.nexin.I	RET	SARP.2	Semaphorin.3A	TrATPase	URB	WFKN2	Aggrecan	ANGL3	BGH3	BGN	C1r	Carbonic.Anhydrase.X	CD109	CD23	CD48	CD5L	CFC1	CNTN2	Contactin.4	Contactin.5	CYTF	Cystatin.M	DLL4	FCG2A	FCG2B	FCG3B	FCGR1	FCN2	GFRa.1	GPC2	Heparin.cofactor.II	HTRA2	IGFBP.7	IL24	LRIG3	LRP8	LY9	MATN2	Nectin.like.protein.2	NET4	PGRP.S	RGMB	RGM.C	TFPI	TSP2	TSP4	ABL1	Aminoacylase.1	Antithrombin.III	AURKB	BARK1	BMP.1	CAMK2A	CAMK2B	Carbonic.anhydrase.6	Carbonic.anhydrase.VII	CDK2.cyclin.A	CDK5.p35	CDK8.cyclin.C	Chk2	CLC4K	CRDL1	CSK	Cathepsin.V	Dkk.4	ECM1	FETUB	Granzyme.H	HCK	IL.17.RD	Kallikrein.7	KPCI	LYNB	PAK3	PAK7	PCI	PIK3CA.PIK3R1	PK3CG	PKB.a.b.g	PLK.1	Renin	SHP.2	STAB2	TBK1	TCPTP	TPSB2	TPSG1	UFC1	Bcl.2	BFL1	BMX	BSP	BTK	CAMK1D	CAMK2D	Carbonic.anhydrase.XIII	CD30.Ligand	CDK1.cyclin.B	Chymase	CSK21	EphA1	EPHA3	FN1.3	FN1.4	Flt.3	FSTL3	granzyme.A	GSK.3.alpha.beta	HIPK3	IL.15.Ra	IL.18.Ra	IL.8	IR	Kallistatin	Kallikrein.6	LCK	LYN	Periostin	PDGF.Rb	PGCB	PRKACA	RPS6KA3	sE.Selectin	STK16	Survivin	Thrombopoietin.Receptor	Thrombospondin.1	TrkA	TRY3	DUS3	XPNPEP1	Angiotensinogen	b2.Microglobulin	b.ECGF	BLC	Catalase	CNTF	FGF.17	GCP.2	IFN.aA	IL.17B	Integrin.a1b1	LEAP.1	Lymphotoxin.a1.b2	Lymphotoxin.a2.b1	MDC	MIP.5	Proteinase.3	SDF.1	TAFI	TARC	TGF.b3	TSH	Vasoactive.Intestinal.Peptide	CD40.ligand..soluble	DKK1	dopa.decarboxylase	Adiponectin	a1.Antitrypsin	a2.HS.Glycoprotein	Arylsulfatase.A	BASI	BMP10	Cadherin.6	CAMK1	Caspase.3	CATE	Chitotriosidase.1	CHL1	CLC7A	MASP3	Discoidin.domain.receptor.2	DKK3	DPP2	Endothelin.converting.enzyme.1	EphB4	FCN1	GNS	HGFA	IL22RA1	LGMN	LY86	Marapsin	MMEL2	MP2K2	MRCKB	Nectin.like.protein.1	NID2	OBCAM	OCAD1	OLR1	RAP	SLAF5	SLIK1	Soggy.1	TEC	TLR4.MD.2.complex	VEGF.sR2	BMPER	Cadherin.12	Calcineurin.B.a	complement.factor.H.related.5	IGF.II.receptor	kallikrein.14	Macrophage.scavenger.receptor	MFRP	Albumin	a2.Macroglobulin	ALT	Angiostatin	CK.MB	p27Kip1	BNP.32	PYY	Secretin	TNR4	CSF.1	Activated.Protein.C	COX.2	STX1a	sTie.2	ADAM.9	ANGL4	Cadherin.2	Carbonic.anhydrase.9	Carbonic.anhydrase.III	CK.BB	Cystatin.S	CYTD	Endocan	EphA5	FGF23	FGFR.2	FGFR.3	FGR	FYN	IL.12.RB2	KPCT	MAPK2	MAPK5	MAPKAPK3	MATK	MK08	PAK6	PDGF.CC	pTEN	PTK6	TLR2	UFM1	AIP	Cyclophilin.A	DLRB1	ETHE1	GAPDH..liver	HSP.40	MDHC	NACA	Peroxiredoxin.1	PPAC	PSA1	PSA6	RS7	RSK.like.protein.kinase	SBDS	SE6L2	SGTA	TCTP	TMA	UB2L3	ARI3A	CaMKK.alpha	CDC37	DLC8	IMB1	ING1	Lamin.B1	LDH.H.1	MBD4	Mesothelin	NAGK	Phosphoglycerate.mutase.1	PLPP	PSD7	SKP1	Sorting.nexin.4	UBE2N	discoidin.domain.receptor.1	FGF.4	HSP.70	sRAGE	BPI	C6	Eotaxin.2	Factor.B	FGF.6	Fibronectin	FST	Granzyme.B	HB.EGF	IgE	IL.17D	IL.17E	IL.20	IL.6.sRa	IL.7	IP.10	Lymphotactin	MCP.4	Neurotrophin.3	Neurotrophin.5	PAPP.A	PDGF.BB	Plasmin	Plasminogen	Prekallikrein	alpha.1.antichymotrypsin.complex	P.Selectin	Tenascin	TGF.b2	Thrombin	uPA	Factor.H	MMP.2	Transferrin	Histone.H2A.z	Thyroglobulin	X14.3.3	X4EBP2	X6.Phosphogluconate.dehydrogenase	Aflatoxin.B1.aldehyde.reductase	AK1A1	AN32B	Cofilin.1	DRG.1	EP15R	ERAB	FER	HNRPQ	IF4G2	IGF.I.sR	IL.1.R4	LCMT1	LIN7B	M2.PK	MDM2	NCAM.L1	NDP.kinase.B	NSF1C	NUDC3	PA2G4	paraoxonase.1	PESC	PFD5	PHI	prostatic.binding.protein	Protein.disulfide.isomerase	PSA2	RAN	RBM39	SNAA	Sphingosine.kinase.1	Spondin.1	Thymidine.kinase	transcription.factor.MLR1..isoform.CRA_b	Transketolase	Triosephosphate.isomerase	XTP3A	PTP.1C	AMNLS	CYTT	BOC	CLC1B	SAA	CRP	sICAM.1	DAPK2	DYRK3	MIC.1	DHH	FGF.12	FGF.16	FGF.8A	IFN.lambda.1	IFN.lambda.2	MSP	SLPI	SP.D	ADAM12	BCL2.like.1.protein	CHST2	CHST6	Collectin.Kidney.1	ENPP7	ENTP3	ENTP5	FCRL3	GREM1	hnRNP.A.B	LRRT1	LRRT3	MFGM	PCSK7	PDPK1	Sialoadhesin	SPARCL1	SPHK2	ST4S6	TGM3	Tropomyosin.2	Ubiquitin	ZAP70	C1.Esterase.Inhibitor	C3b	C4	C5b..6.Complex	FGF7	IL.3.Ra	IL.5.Ra	IL.11	Kininogen..HMW	MMP.12	NCAM.120	PDGF.AA	SCGF.alpha	ATS15	BSSP4	BST1	CBX5	CDON	Clusterin	CONA1	CTAP.III	DnaJ.homolog	EMR2	FLRT1	Fucosyltransferase.3	FUT5	GP114	HDGR2	IL.34	KIRR3	KYNU	Livin.B	NXPH1	PLCG1	PLXC1	RSPO2	SH21A	SLIK5	SORC2	PH	IL.6	X3HIDH	GM.CSF	TNF.b	X41	X17.beta.HSD.1	Apo.D	IL.3	PPIB	Protein.disulfide.isomerase.A3	TFF3	Afamin	Olfactomedin.4	ASM3A	FAM107B	Gelsolin	CBG	Cytidylate.kinase	C34.gp41.HIV.Fragment	PERL	CO8A1	ITI.heavy.chain.H4	TXD12	STRATIFIN	sL.Selectin	TRAIL.R1	Epithelial.cell.kinase	G.CSF	Glypican.3	IL.1a	BMPR1A	BMP.RII	TrkB	VEGF121	Angiogenin	Coagulation.Factor.IX	Coagulation.Factor.X	GDF2	Insulin	MCP.3	WNT7A	ACTH	Glucagon	C3a	Calcineurin	Caspase.2	Coactosin.like.protein	Coagulation.Factor.V	D.dimer	Endoglin	Galectin.8	GIB	Glutathione.S.transferase.Pi	GOT1	HCC.4	HCG	Hemoglobin	IgD	Integrin.aVb5	Lysozyme	MIP.3b	MIS	MMP.1	MMP.13	SHBG	Stanniocalcin.1	TF	EPI	X40S.ribosomal.protein.SA	AGR2	annexin.I	annexin.II	ARMEL	ARP19	ARTS1	ATP.synthase.beta.chain	C1QBP	CAPG	Carbonic.anhydrase.I	carbonic.anhydrase.II	CATZ	cIAP.2	CRK	DBNL	DERM	DSC3	Elafin	ERP29	Esterase.D	FABPE	FAK1	FCAR	FGFR4	Fibrinogen.g.chain.dimer	GP1BA	GPC5	GRN	GSTA3	hnRNP.K	HPG.	HRG	IF4A3	JAK2	LG3BP	Mammaglobin.2	MMP.14	MK11	MK12	MK13	MAPK14	Mn.SOD	Moesin	PBEF	Myokinase..human	NCC27	NCK1	PAFAH	PARK7	Peroxiredoxin.5	Peroxiredoxin.6	PGP9.5	phosphoglycerate.kinase.1	PPase	PUR8	Rb	RS3	sCD163	SEPR	SIRT2	SPTA2	SSRP1	Tropomyosin.1.alpha.chain	Trypsin.2	TS	TSG.6	B7.H1	B7.H2	CD226	CD244	CD83	CLM6	CRTAM	DAF	DcR3	EPHAA	EPHB2	EphB6	GPNMB	IL.1.sR9	IL.17B.R	IL.20.Ra	IL.22BP	IL.23.R	IL.7.Ra	ILT.2	ILT.4	JAG1	JAG2	JAML1	KI2L4	KI3L2	KI3S1	KLRF1	LAG.3	LIMP.II	MICB	MO2R1	NKp46	Nogo.Receptor	NOTC2	Notch.1	Notch.3	Nr.CAM	NRX1B	NRX3B	OX2G	Prolactin.Receptor	RELT	ROBO2	ROBO3	SEM6B	Semaphorin.6A	sICAM.5	SIG14	SLAF6	SREC.I	SREC.II	TAJ	TCCR	TGF.b.R.II	TIMD3	TWEAKR	UNC5H3	UNC5H4	PDE7A	AMPK.a1b1g1	K.ras	NMT1	PDE9A	PPID	PSME3	GCKR	CK2.A1.B	CK2.A2.B	PDK1	KIF23	IMDH1	HMGR	PCSK9	NR1D1	PPIE	MP2K4	JNK2	AMPK.a2b2g1	cGMP.stimulated.PDE	Cyclophilin.F	DRAK2	IMDH2	PDE11	PDE1A	PDE3A	PDE4D	PDE5A	TAK1.TAB1	TYK2	ABL2	BCAR3	calreticulin	GRB2.related.adapter.protein.2	MMP.16	RAC3	SHC1	VAV	GHC2	Eotaxin	Coagulation.Factor.IXab	Elastase	Apo.E2	Troponin.T	Prothrombin	EGFRvIII	annexin.VI	B7.2	calgranulin.B	Caspase.10	CBPE	CKAP2	CPNE1	Cyclin.B1	DLL1	GPC6	hnRNP.A2.B1	HVEM	IL.1Ra	Keratin.18	LIGHT	MIF	NLGNX	OMD	PIM1	PKB.beta	Semaphorin.3E	SET	BAFF.Receptor	BRF.1	Fas..soluble	sLeptin.R	DR6	CAD15	CD27	RANK	SHPS1	FABP	Troponin.I..skeletal..fast.twitch	Troponin.I	ANP	ALCAM	ASGR1	CNDP1	COLEC12	CYTN	DEAD.box.protein.19B	Ficolin.3	GAS1	GRB2.adapter.protein	H6ST1	HSP.90b	IL.17.RC	MED.1	PKC.B.II	PKC.G	PSMA	RANTES	RASA1	RBP	RGMA	RS3A	sICAM.2	SLAF7	SRCN1	Stress.induced.phosphoprotein.1	Testican.1	Testican.2	WNK3	RUXF	Cathepsin.D	EGF	GITR	bFGF.R	TRAIL.R2	NRP1	AFP	BID	b.NGF	C3d	CD70	Cripto	Epo	GDNF	IFN.g.R1	IL.9	LIF.sR	NG36	Noggin	S100A12	tau	X14.3.3.protein.zeta.delta	X3HAO	aldolase.A	ARGI1	BAD	Dynactin.subunit.2	EF.1.beta	eIF.4H	eIF.5A.1	Gastrin.releasing.peptide	HINT1	HSP70.protein.8	Nucleoside.diphosphate.kinase.A	PEX5	PSME1	S100A7	WISP.3	Ferritin	TNF.a	TWEAK	Tpo	PTH	Somatostatin.28	MP2K3	p53	PolyUbiquitin.K48	PolyUbiquitin.K63	NET1	CD47	ANK2	X14.3.3.protein.theta	CREL1	Lectin..mannose.binding.2	LRP1B	MYPC1	N.terminal.pro.BNP	Tropomyosin.4	PACAP.27	ghrelin	PACAP.38	a.Synuclein	BMP.6	HGH	SOD3	RSPO4	Cathepsin.H	Activin.AB	PSA	IGFBP.2	RNase.H1	ROR1	CgA	MMP.10	FBLN3	Leptin	KEAP1	gpIIbIIIa	Eotaxin.3	SUMO3	IL.17	CSRP3	MMP.8	PGM1	DSCAM	MUC1	FAM3B	NEUREGULIN.1	INGR2	sLRP1	IFN.a.b.R1	TFF1	HMGN1	MIG	CD63	Trefoil.factor.2	Galectin.7	LEG9	UB2G2	Transgelin.2	ATPO	Corticotropin.lipotropin	QORL1	PEDF	CATF	FTCD	UBP25	PLXB2
PDAG965NUZ	0	76	76	2	Male	6	20	PD	UTSW	76.3	20	31	Male	Set.2	1591.7	1181.1	24859.2	1403.1	1662.2	2469.4	1371.1	3487.8	1320.0	390.8	466.4	25208.5	28676.8	788.3	71680.7	275.9	15660.6	677.1	2365.5	1399.2	290.9	1051.4	7693.5	633.9	4204.6	1424.0	499.4	1513.2	10491.9	4375.2	57221.5	35136.7	685.0	1957.9	2871.6	6520.2	534.1	476.0	3090.9	1362.5	1319.3	317.1	654.6	484.1	39947.5	22586.6	4984.5	1960.1	1364.7	1145.2	5653.7	1660.0	30873.7	4875.8	1248.4	762.6	2919.2	2967.8	3240.2	16120.1	5356.1	6382.4	75466.9	3241.9	191.7	634.3	1212.6	6599.0	1816.0	4219.2	2109.5	1904.9	1225.9	965.6	428.2	702.1	1024	15825.7	531.2	352.3	256.3	14755.6	1691.0	10803.4	2669.9	1686.9	11676.7	713.4	12413.4	699.6	1839.9	782.3	525.6	434.3	1665	1878.2	30519.8	1283.1	1022.2	3918.6	215.9	1559.1	1357.7	51358.3	70.1	565.6	172.2	401.3	1948.8	6518.7	8224.9	41634.0	1493.0	3268.4	948.1	11759.7	233.8	774.0	310.3	347.0	144.3	36729.8	16656.7	1362.3	742.9	66564.3	837.4	925.7	5129.0	21426.9	5480.5	14337.0	809.4	42455.7	1690.8	829.4	8437.7	19629.8	1750.8	11962.7	312.1	350.1	118.6	577.7	969.7	477.5	2448.6	552.3	1345.0	1665.9	2968.4	432.0	298.5	166.4	474.1	6558.1	438.4	354.7	2332.8	10805.6	27569.5	1165.8	506.0	3071.7	4470.6	1563.5	5618.9	14019.2	199.3	540.3	7366.2	28630.5	72880.2	910.7	24148.3	642.3	11144.0	1143.5	5846.6	9902.5	3937.4	62630.3	527.3	24934.8	1212.8	32018.5	6127.1	2173.9	714.3	2804.0	3094.9	1982.0	1020.9	285.5	87348.2	2541.9	1176	1338.4	37511.4	644.9	8302.8	3755.0	382.5	951.5	2067.8	2886.5	273.7	2998.1	185.1	389.6	684.2	183.9	1127.4	1386.7	225088.3	1517	938.1	3460.8	16618.3	308.5	3474.0	48185.8	72494.5	181021.8	305.9	269.9	5088.5	375.2	461.3	801.4	994.4	171.2	2807.1	712.1	185.3	326.4	643.8	844.9	43968.8	427.4	1510.5	249.0	453.5	1802.9	18221.6	1259.4	188805.7	12107.6	553.1	301.4	171.1	921.5	1608.8	1802.4	11110.8	1828.2	4142.2	1491.2	2840.0	7616.2	707.5	1070.4	296.6	2836.3	254.7	22978.7	9370.2	933.2	371.1	2800.1	1838.8	7815.7	3285.7	2742.0	3331.8	7055.5	536.5	40683.4	262.3	371.5	2377.9	307.9	414.6	1418.0	4796.1	49466.2	2350.9	535.2	508.6	3160.1	1309.3	329542.6	1839.4	773.6	5456.3	956.3	6410.6	597.2	20624.3	2312.6	192.9	2541.2	1799.4	258273.0	257445.1	510.7	2507.0	24718.2	983.0	773.9	1080.2	711.2	783.8	5342.9	1096.1	847.8	108637.8	868.8	991.5	1869.9	9745.2	881.5	1343.5	4230.8	913.6	9335.7	322.4	2017.7	2455.6	1983.0	518.0	4777.6	677.1	8659.9	1073.7	805.5	690.6	9998.6	1008.1	326.7	661.4	8603.1	6301.7	1677.0	19673.9	504.4	3378.3	3797.7	14123.2	28690.8	423.5	116.7	1756.4	1568.2	4309.6	53610.1	2464.0	46849.4	767.7	502.7	3514.4	5320.0	2360.6	2655.1	742.8	3495.3	1232.2	38113.5	5671.8	1526.0	1506.2	4310.4	37104.0	489.7	461.2	36787.4	218.4	490.0	5023.2	1363.1	82103.8	1950.6	466.4	19539.3	593.0	3418.7	898.6	779.4	9255.1	92707.9	1991.6	312.7	2088.0	440.7	489.5	791.9	1141.1	13840.5	6225.3	1604.0	366.8	1041.3	10592.2	3717.6	501.3	1311.1	43942.4	28063.0	859.4	9425.7	400.0	2766.4	1970.8	626.4	11630.2	1071.2	1554.2	348	2697.4	258	242.3	793.1	2219.2	16515.6	1390.9	1199.4	2169.0	4049.8	4464.6	1423.9	181.8	3937.3	1045.0	368.5	536.6	229.5	7304.3	3048.2	7308.5	3007.8	2059.8	765	4099.4	1812.1	8078.3	2659.4	7201.2	470.9	412.2	41984.0	2427.3	3619.0	652.5	4998.0	1884.6	705.6	2831.9	3498.0	1196.4	4537.1	669.7	822.9	12259.1	435.7	2475.3	1370.1	1328.0	282.7	1114.3	950.2	159.0	3669.4	7624.8	51411.6	294.1	5651.3	2217.2	2077.2	10543.6	2351.4	844.0	457.6	2197.6	1099.3	38792.3	13916.1	310.8	137.7	3670.1	133119.1	745.5	12011.6	2976.7	2079.4	5228.5	4716.7	318.7	1020.0	1275.8	2122.9	382.9	180.9	4092	16296.9	1281.0	8574.0	24249.6	4601.4	240.1	649.6	538.9	1220.7	4043.1	86224.1	1088.6	788.4	98553.7	937.2	2767.2	8696.6	188.7	845.5	12164.1	863.8	484.6	351.6	2302.3	190.1	26436.1	1578.6	1139.2	321	3656.9	19102.7	2228.7	17038	6246.4	2019.3	762.7	592.8	758.1	4015.8	137.9	4646.5	84330.0	5011.1	6217.2	2201.8	23735.4	555.2	800.9	9534.6	767.9	8130.0	42594.8	2292.9	354.7	19149.5	6756.4	7873.4	1957.5	2795.3	2126.2	13577.0	1918.6	578.9	243.3	6530.5	3353.7	457.5	3902.2	7626.2	5564.2	1706.8	186.6	2298.1	16356.7	219.9	196.0	1179.0	148.0	164.0	2137.8	17545.3	99	1843.1	1323.4	4900.3	4706.2	5107.3	14298.1	1536.0	466.2	575.8	391.2	1392.2	38874.4	318.5	5537.6	1280.7	1810.8	1481.3	429.3	1471.6	657.8	5778.6	21619.4	422.5	2747.1	14980.5	829.7	5096.0	1511.4	7772.9	1729.0	19403.9	3327.2	2298.2	2780.7	1726.1	888.3	2831.8	5397.4	6920.5	1140.0	1206.0	1491.1	1635.2	3660.8	5810.2	1055.2	1646.5	893.2	9551.1	1672.2	3053.6	8949.0	3955.3	5576.8	511.7	858.7	7819.1	1450.5	28456.2	8281.9	895.5	2059.6	18869.5	10666.4	3809.9	20041.0	338.3	700.5	597.7	3016.1	197.0	788.4	1218.5	891.5	545.2	341.8	1753.9	13043.2	4242.7	1750.4	1146.8	1750.4	710.4	151.4	9594.0	1452.1	792.6	796.3	243.6	910.1	7175.9	25505.2	1576.0	8383.8	13404.6	636.0	2037.5	359.0	1844.4	20365.6	406.6	717.9	254.9	620.7	8071.7	14248.1	166090.2	3361.2	3238.0	121254.6	1314.1	27096.4	8689.0	2863.5	10680.5	604.4	1194.2	1001.0	284.2	27318.4	3490.7	5690.0	19178.2	1688.3	2217.9	858.2	530.7	656.5	1619.3	12143.3	31645.8	832.7	1464.8	487.3	396.1	1098.8	2038.5	5359.8	365.1	5579.5	19308.4	8654.9	371.8	261.9	6754.0	674.9	776.5	84197.8	345.3	24984.8	446.3	24298.9	860.1	205.4	354.5	4276.3	214.3	990.5	403.0	16251.4	240.8	1382.6	360.7	417.3	328.7	216.7	19932.8	68559.1	782.5	4282.3	22795.5	10035.3	30642.0	16977.3	252.6	1466.3	1953.8	63034.8	8384.7	251749.4	1505.3	405.8	7727.6	287.9	22711.9	7474.9	4893.4	179.4	12576.8	62304.7	913.3	6416	7847.3	2831.1	6694.3	7883.0	9226.8	1812.9	442.4	63355.5	277.6	492.8	34275.1	907.2	504.9	2703.6	202.1	214.9	402.2	27206.1	8114.9	231.6	668.9	9248.8	374.1	12484.8	23014.0	2287.7	557.1	230.2	60993.3	12186.5	11121.7	10160.3	168.4	18865.8	1252.3	30450.2	743.0	19977.1	3817.7	4761.0	2233.1	1397.1	805.6	211.6	3477.1	3199.4	380.2	148.1	4064.5	28269.8	5864.5	443.6	1985.4	384.3	269.1	7478.9	4802.2	1380.7	4012.7	366.5	424.5	1734.0	116.5	191.1	740.7	1742.1	3150.3	101.4	12477.5	588.1	4892.5	445.7	1948.7	1470.5	11732.3	13122.1	10417.7	127874.4	494.2	2182.4	1461.3	1306.6	294.0	18385.9	1651.6	15069.6	30073.8	4439.4	385.8	1910.1	10705.1	415.8	5970.1	1492.5	706.8	51945.8	755.6	668.1	1140.0	592.1	12069.6	624.5	715.6	681.2	312.1	739.8	112.8	10144.6	515.2	743.1	383.3	3913.1	3001.7	419.0	2795.2	660.5	606.7	295.4	440.9	8105.7	1803.5	4912.3	3478.7	3140.6	5871.8	10637.4	26374.9	161.1	4208.6	2471	1056.2	704.5	5160.0	799.9	912.6	551.2	45561.8	2127.3	736.4	5601.8	1440.5	2843.5	3713.5	1056.0	689.8	917.6	505.4	1010.8	672.7	2894.2	6250.9	2226.6	2682.8	147.3	682.6	275.1	458.4	4463.2	198.6	2617.5	371.6	3461.7	71107.2	17738.7	1421.1	522.9	719.3	5937.1	3002.9	22976.3	593.4	2823.8	1706.3	1060.1	105011.0	322.5	10727.9	820.1	562.6	5131.1	1938.9	1608.1	982.7	1510.3	780.0	9103.2	5531.6	3592.7	3490.2	87027.7	2984.2	5450.8	884.2	13235.8	237.6	5764.5	237.0	10719.1	4293.6	3760.6	341.4	8603.7	7362.9	3834.9	889.2	317.7	224.7	1189.0	79394.2	1758.1	736.3	23710.3	172	291.9	1469.8	4333.4	540.5	116972.1	749.2	10073.2	1082.8	822.6	1396.7	489.1	3466.1	54020	2120.1	512.2	29629.4	10168.6	1123.4	900.5	822.9	577.7	399.6	2191.8	5000.7	35316.5	1338.4	2368.4	961.0	3063.2	641.7	5980.0	189.0	453.4	974.6	1953.2	363.4	1531.7	1024.3	1861.0	900.6	180.7	400.7	4394.2	1322.5	16040.8	572.2	389.4	18570.1	1704.9	5058.3	924.5	1299.3	279.0	1588.2	5261.3	290.4	4101.6	8151.1	604.5	412.2	567.3	1171.0	300.0	429.6	349.8	5227.5	618.1	795.3	907.2	2263.5	1248.3	1048.8	21944.1	645.0	16456.0	852.0	1103.0	2419.3	1255.8	2369.4	3667.3	372.4	3890.4	10319.3	1300.3	20466.8	446.6	9121.5	284.4	757.0	1352.8	814.9	8321.8	181.8	3755.9	5745.9	414.8	428.8	1113.8	5083.5	462.0	27509.0	278.1	477.3	14272.9	573.1	2156.9	1165.8	2596.4	361	631.5	550.1	1835.4	44495.2	1043.4	12265.9	6825.2	31793.1	4384.5	3380.5	4122.4	914.9	1497.5	1260.7	26841.3	4391.2	2491.2	1837.6	1748.6	3453.1	634.7	930.7	14941.3	22715.1	33135.7	889.6	9870.6	4395.5	528.5	334398.4	3157.9	127148.1	202.7	14978.2	1053.9	3867.6	4097.2	1664.5	14611.1	3633.3	938.0	2209.0	1772.9	3386.7	713.2	3553.9	1069.0	730.6	1642.7	937.3	7045.0	982.0	22910.2	3695.1	761.1	2284.1	1982.7	4273.8	3759.6	7486.8	4083.2	7014.4	1238.4	9609.4	11961.7	5102.3	845.6	832.8	17793.9	1215.4	8224.1	2405.2	1313.5	6926.2	508.2	780.5	58638.3	2346.4	57372.2	999.3	71002.7	15157.0	500.8	523.4	57557.0	2085.5	322.5	25211.4	967.3	1431.4	3617.9	102012.3	12657.5	3206.2	903.6	1999.2	2754.9	1052.7	2043.2	752.7	797.9	381.3	3111.4	854.1	3034.1	567.8	8083.3	282.6	2150.6	980.8	372.3	470.6	236.9	4634.8	715.6	4747.5	722.7	181.6	188129.3	5750.6	97979.7	2291.6	15313.5	1343.0	688.8	11073.1	47034.9	556.0	1626.8	1889.4	1838.8	1907.8	1370.4	299.0	1453.5	9211.1	515.3	746.4	229.4	2312.5	1562.8	3295.4	1099.0	1826.3	5250.4	423.2	940.3	513.0	1500.0	3907.6	13183.5	39637.7	1589.9	18272.9	146051.5	329.3	804.6	210.0	15740.1	18865.7	327.2	437.5	392.8	1136.4	805.9	3555.8	1109.2	234.3	759.2	7830.5	689.9	2022.8	3570.5	1338.4	1766.3	854.1	4236.0	368.9	4778.9	1234.7	656.5	1042.1	1209.8	1272.9	157.8	428.0	2019.8	1649.4	2724.6	648.8	532.4	401.7	7170.7	789.2	1254.3	6504.0	8694.6	7546.4	747.6	2157.8	55489.3	3647.6	3005.5	3903.4	4412.9
PDAG965NUZ	1	76	77	3	Male	14	20	PD	UTSW	76.3	20	31	Male	Set.2	1591.7	1181.1	24859.2	1403.1	1662.2	2469.4	1371.1	3487.8	1320.0	390.8	466.4	25208.5	28676.8	788.3	71680.7	275.9	15660.6	677.1	2365.5	1399.2	290.9	1051.4	7693.5	633.9	4204.6	1424.0	499.4	1513.2	10491.9	4375.2	57221.5	35136.7	685.0	1957.9	2871.6	6520.2	534.1	476.0	3090.9	1362.5	1319.3	317.1	654.6	484.1	39947.5	22586.6	4984.5	1960.1	1364.7	1145.2	5653.7	1660.0	30873.7	4875.8	1248.4	762.6	2919.2	2967.8	3240.2	16120.1	5356.1	6382.4	75466.9	3241.9	191.7	634.3	1212.6	6599.0	1816.0	4219.2	2109.5	1904.9	1225.9	965.6	428.2	702.1	1024	15825.7	531.2	352.3	256.3	14755.6	1691.0	10803.4	2669.9	1686.9	11676.7	713.4	12413.4	699.6	1839.9	782.3	525.6	434.3	1665	1878.2	30519.8	1283.1	1022.2	3918.6	215.9	1559.1	1357.7	51358.3	70.1	565.6	172.2	401.3	1948.8	6518.7	8224.9	41634.0	1493.0	3268.4	948.1	11759.7	233.8	774.0	310.3	347.0	144.3	36729.8	16656.7	1362.3	742.9	66564.3	837.4	925.7	5129.0	21426.9	5480.5	14337.0	809.4	42455.7	1690.8	829.4	8437.7	19629.8	1750.8	11962.7	312.1	350.1	118.6	577.7	969.7	477.5	2448.6	552.3	1345.0	1665.9	2968.4	432.0	298.5	166.4	474.1	6558.1	438.4	354.7	2332.8	10805.6	27569.5	1165.8	506.0	3071.7	4470.6	1563.5	5618.9	14019.2	199.3	540.3	7366.2	28630.5	72880.2	910.7	24148.3	642.3	11144.0	1143.5	5846.6	9902.5	3937.4	62630.3	527.3	24934.8	1212.8	32018.5	6127.1	2173.9	714.3	2804.0	3094.9	1982.0	1020.9	285.5	87348.2	2541.9	1176	1338.4	37511.4	644.9	8302.8	3755.0	382.5	951.5	2067.8	2886.5	273.7	2998.1	185.1	389.6	684.2	183.9	1127.4	1386.7	225088.3	1517	938.1	3460.8	16618.3	308.5	3474.0	48185.8	72494.5	181021.8	305.9	269.9	5088.5	375.2	461.3	801.4	994.4	171.2	2807.1	712.1	185.3	326.4	643.8	844.9	43968.8	427.4	1510.5	249.0	453.5	1802.9	18221.6	1259.4	188805.7	12107.6	553.1	301.4	171.1	921.5	1608.8	1802.4	11110.8	1828.2	4142.2	1491.2	2840.0	7616.2	707.5	1070.4	296.6	2836.3	254.7	22978.7	9370.2	933.2	371.1	2800.1	1838.8	7815.7	3285.7	2742.0	3331.8	7055.5	536.5	40683.4	262.3	371.5	2377.9	307.9	414.6	1418.0	4796.1	49466.2	2350.9	535.2	508.6	3160.1	1309.3	329542.6	1839.4	773.6	5456.3	956.3	6410.6	597.2	20624.3	2312.6	192.9	2541.2	1799.4	258273.0	257445.1	510.7	2507.0	24718.2	983.0	773.9	1080.2	711.2	783.8	5342.9	1096.1	847.8	108637.8	868.8	991.5	1869.9	9745.2	881.5	1343.5	4230.8	913.6	9335.7	322.4	2017.7	2455.6	1983.0	518.0	4777.6	677.1	8659.9	1073.7	805.5	690.6	9998.6	1008.1	326.7	661.4	8603.1	6301.7	1677.0	19673.9	504.4	3378.3	3797.7	14123.2	28690.8	423.5	116.7	1756.4	1568.2	4309.6	53610.1	2464.0	46849.4	767.7	502.7	3514.4	5320.0	2360.6	2655.1	742.8	3495.3	1232.2	38113.5	5671.8	1526.0	1506.2	4310.4	37104.0	489.7	461.2	36787.4	218.4	490.0	5023.2	1363.1	82103.8	1950.6	466.4	19539.3	593.0	3418.7	898.6	779.4	9255.1	92707.9	1991.6	312.7	2088.0	440.7	489.5	791.9	1141.1	13840.5	6225.3	1604.0	366.8	1041.3	10592.2	3717.6	501.3	1311.1	43942.4	28063.0	859.4	9425.7	400.0	2766.4	1970.8	626.4	11630.2	1071.2	1554.2	348	2697.4	258	242.3	793.1	2219.2	16515.6	1390.9	1199.4	2169.0	4049.8	4464.6	1423.9	181.8	3937.3	1045.0	368.5	536.6	229.5	7304.3	3048.2	7308.5	3007.8	2059.8	765	4099.4	1812.1	8078.3	2659.4	7201.2	470.9	412.2	41984.0	2427.3	3619.0	652.5	4998.0	1884.6	705.6	2831.9	3498.0	1196.4	4537.1	669.7	822.9	12259.1	435.7	2475.3	1370.1	1328.0	282.7	1114.3	950.2	159.0	3669.4	7624.8	51411.6	294.1	5651.3	2217.2	2077.2	10543.6	2351.4	844.0	457.6	2197.6	1099.3	38792.3	13916.1	310.8	137.7	3670.1	133119.1	745.5	12011.6	2976.7	2079.4	5228.5	4716.7	318.7	1020.0	1275.8	2122.9	382.9	180.9	4092	16296.9	1281.0	8574.0	24249.6	4601.4	240.1	649.6	538.9	1220.7	4043.1	86224.1	1088.6	788.4	98553.7	937.2	2767.2	8696.6	188.7	845.5	12164.1	863.8	484.6	351.6	2302.3	190.1	26436.1	1578.6	1139.2	321	3656.9	19102.7	2228.7	17038	6246.4	2019.3	762.7	592.8	758.1	4015.8	137.9	4646.5	84330.0	5011.1	6217.2	2201.8	23735.4	555.2	800.9	9534.6	767.9	8130.0	42594.8	2292.9	354.7	19149.5	6756.4	7873.4	1957.5	2795.3	2126.2	13577.0	1918.6	578.9	243.3	6530.5	3353.7	457.5	3902.2	7626.2	5564.2	1706.8	186.6	2298.1	16356.7	219.9	196.0	1179.0	148.0	164.0	2137.8	17545.3	99	1843.1	1323.4	4900.3	4706.2	5107.3	14298.1	1536.0	466.2	575.8	391.2	1392.2	38874.4	318.5	5537.6	1280.7	1810.8	1481.3	429.3	1471.6	657.8	5778.6	21619.4	422.5	2747.1	14980.5	829.7	5096.0	1511.4	7772.9	1729.0	19403.9	3327.2	2298.2	2780.7	1726.1	888.3	2831.8	5397.4	6920.5	1140.0	1206.0	1491.1	1635.2	3660.8	5810.2	1055.2	1646.5	893.2	9551.1	1672.2	3053.6	8949.0	3955.3	5576.8	511.7	858.7	7819.1	1450.5	28456.2	8281.9	895.5	2059.6	18869.5	10666.4	3809.9	20041.0	338.3	700.5	597.7	3016.1	197.0	788.4	1218.5	891.5	545.2	341.8	1753.9	13043.2	4242.7	1750.4	1146.8	1750.4	710.4	151.4	9594.0	1452.1	792.6	796.3	243.6	910.1	7175.9	25505.2	1576.0	8383.8	13404.6	636.0	2037.5	359.0	1844.4	20365.6	406.6	717.9	254.9	620.7	8071.7	14248.1	166090.2	3361.2	3238.0	121254.6	1314.1	27096.4	8689.0	2863.5	10680.5	604.4	1194.2	1001.0	284.2	27318.4	3490.7	5690.0	19178.2	1688.3	2217.9	858.2	530.7	656.5	1619.3	12143.3	31645.8	832.7	1464.8	487.3	396.1	1098.8	2038.5	5359.8	365.1	5579.5	19308.4	8654.9	371.8	261.9	6754.0	674.9	776.5	84197.8	345.3	24984.8	446.3	24298.9	860.1	205.4	354.5	4276.3	214.3	990.5	403.0	16251.4	240.8	1382.6	360.7	417.3	328.7	216.7	19932.8	68559.1	782.5	4282.3	22795.5	10035.3	30642.0	16977.3	252.6	1466.3	1953.8	63034.8	8384.7	251749.4	1505.3	405.8	7727.6	287.9	22711.9	7474.9	4893.4	179.4	12576.8	62304.7	913.3	6416	7847.3	2831.1	6694.3	7883.0	9226.8	1812.9	442.4	63355.5	277.6	492.8	34275.1	907.2	504.9	2703.6	202.1	214.9	402.2	27206.1	8114.9	231.6	668.9	9248.8	374.1	12484.8	23014.0	2287.7	557.1	230.2	60993.3	12186.5	11121.7	10160.3	168.4	18865.8	1252.3	30450.2	743.0	19977.1	3817.7	4761.0	2233.1	1397.1	805.6	211.6	3477.1	3199.4	380.2	148.1	4064.5	28269.8	5864.5	443.6	1985.4	384.3	269.1	7478.9	4802.2	1380.7	4012.7	366.5	424.5	1734.0	116.5	191.1	740.7	1742.1	3150.3	101.4	12477.5	588.1	4892.5	445.7	1948.7	1470.5	11732.3	13122.1	10417.7	127874.4	494.2	2182.4	1461.3	1306.6	294.0	18385.9	1651.6	15069.6	30073.8	4439.4	385.8	1910.1	10705.1	415.8	5970.1	1492.5	706.8	51945.8	755.6	668.1	1140.0	592.1	12069.6	624.5	715.6	681.2	312.1	739.8	112.8	10144.6	515.2	743.1	383.3	3913.1	3001.7	419.0	2795.2	660.5	606.7	295.4	440.9	8105.7	1803.5	4912.3	3478.7	3140.6	5871.8	10637.4	26374.9	161.1	4208.6	2471	1056.2	704.5	5160.0	799.9	912.6	551.2	45561.8	2127.3	736.4	5601.8	1440.5	2843.5	3713.5	1056.0	689.8	917.6	505.4	1010.8	672.7	2894.2	6250.9	2226.6	2682.8	147.3	682.6	275.1	458.4	4463.2	198.6	2617.5	371.6	3461.7	71107.2	17738.7	1421.1	522.9	719.3	5937.1	3002.9	22976.3	593.4	2823.8	1706.3	1060.1	105011.0	322.5	10727.9	820.1	562.6	5131.1	1938.9	1608.1	982.7	1510.3	780.0	9103.2	5531.6	3592.7	3490.2	87027.7	2984.2	5450.8	884.2	13235.8	237.6	5764.5	237.0	10719.1	4293.6	3760.6	341.4	8603.7	7362.9	3834.9	889.2	317.7	224.7	1189.0	79394.2	1758.1	736.3	23710.3	172	291.9	1469.8	4333.4	540.5	116972.1	749.2	10073.2	1082.8	822.6	1396.7	489.1	3466.1	54020	2120.1	512.2	29629.4	10168.6	1123.4	900.5	822.9	577.7	399.6	2191.8	5000.7	35316.5	1338.4	2368.4	961.0	3063.2	641.7	5980.0	189.0	453.4	974.6	1953.2	363.4	1531.7	1024.3	1861.0	900.6	180.7	400.7	4394.2	1322.5	16040.8	572.2	389.4	18570.1	1704.9	5058.3	924.5	1299.3	279.0	1588.2	5261.3	290.4	4101.6	8151.1	604.5	412.2	567.3	1171.0	300.0	429.6	349.8	5227.5	618.1	795.3	907.2	2263.5	1248.3	1048.8	21944.1	645.0	16456.0	852.0	1103.0	2419.3	1255.8	2369.4	3667.3	372.4	3890.4	10319.3	1300.3	20466.8	446.6	9121.5	284.4	757.0	1352.8	814.9	8321.8	181.8	3755.9	5745.9	414.8	428.8	1113.8	5083.5	462.0	27509.0	278.1	477.3	14272.9	573.1	2156.9	1165.8	2596.4	361	631.5	550.1	1835.4	44495.2	1043.4	12265.9	6825.2	31793.1	4384.5	3380.5	4122.4	914.9	1497.5	1260.7	26841.3	4391.2	2491.2	1837.6	1748.6	3453.1	634.7	930.7	14941.3	22715.1	33135.7	889.6	9870.6	4395.5	528.5	334398.4	3157.9	127148.1	202.7	14978.2	1053.9	3867.6	4097.2	1664.5	14611.1	3633.3	938.0	2209.0	1772.9	3386.7	713.2	3553.9	1069.0	730.6	1642.7	937.3	7045.0	982.0	22910.2	3695.1	761.1	2284.1	1982.7	4273.8	3759.6	7486.8	4083.2	7014.4	1238.4	9609.4	11961.7	5102.3	845.6	832.8	17793.9	1215.4	8224.1	2405.2	1313.5	6926.2	508.2	780.5	58638.3	2346.4	57372.2	999.3	71002.7	15157.0	500.8	523.4	57557.0	2085.5	322.5	25211.4	967.3	1431.4	3617.9	102012.3	12657.5	3206.2	903.6	1999.2	2754.9	1052.7	2043.2	752.7	797.9	381.3	3111.4	854.1	3034.1	567.8	8083.3	282.6	2150.6	980.8	372.3	470.6	236.9	4634.8	715.6	4747.5	722.7	181.6	188129.3	5750.6	97979.7	2291.6	15313.5	1343.0	688.8	11073.1	47034.9	556.0	1626.8	1889.4	1838.8	1907.8	1370.4	299.0	1453.5	9211.1	515.3	746.4	229.4	2312.5	1562.8	3295.4	1099.0	1826.3	5250.4	423.2	940.3	513.0	1500.0	3907.6	13183.5	39637.7	1589.9	18272.9	146051.5	329.3	804.6	210.0	15740.1	18865.7	327.2	437.5	392.8	1136.4	805.9	3555.8	1109.2	234.3	759.2	7830.5	689.9	2022.8	3570.5	1338.4	1766.3	854.1	4236.0	368.9	4778.9	1234.7	656.5	1042.1	1209.8	1272.9	157.8	428.0	2019.8	1649.4	2724.6	648.8	532.4	401.7	7170.7	789.2	1254.3	6504.0	8694.6	7546.4	747.6	2157.8	55489.3	3647.6	3005.5	3903.4	4412.9
PDAG965NUZ	2	76	78	4	Male	21	20	PD	UTSW	76.3	20	31	Male	Set.2	1591.7	1181.1	24859.2	1403.1	1662.2	2469.4	1371.1	3487.8	1320.0	390.8	466.4	25208.5	28676.8	788.3	71680.7	275.9	15660.6	677.1	2365.5	1399.2	290.9	1051.4	7693.5	633.9	4204.6	1424.0	499.4	1513.2	10491.9	4375.2	57221.5	35136.7	685.0	1957.9	2871.6	6520.2	534.1	476.0	3090.9	1362.5	1319.3	317.1	654.6	484.1	39947.5	22586.6	4984.5	1960.1	1364.7	1145.2	5653.7	1660.0	30873.7	4875.8	1248.4	762.6	2919.2	2967.8	3240.2	16120.1	5356.1	6382.4	75466.9	3241.9	191.7	634.3	1212.6	6599.0	1816.0	4219.2	2109.5	1904.9	1225.9	965.6	428.2	702.1	1024	15825.7	531.2	352.3	256.3	14755.6	1691.0	10803.4	2669.9	1686.9	11676.7	713.4	12413.4	699.6	1839.9	782.3	525.6	434.3	1665	1878.2	30519.8	1283.1	1022.2	3918.6	215.9	1559.1	1357.7	51358.3	70.1	565.6	172.2	401.3	1948.8	6518.7	8224.9	41634.0	1493.0	3268.4	948.1	11759.7	233.8	774.0	310.3	347.0	144.3	36729.8	16656.7	1362.3	742.9	66564.3	837.4	925.7	5129.0	21426.9	5480.5	14337.0	809.4	42455.7	1690.8	829.4	8437.7	19629.8	1750.8	11962.7	312.1	350.1	118.6	577.7	969.7	477.5	2448.6	552.3	1345.0	1665.9	2968.4	432.0	298.5	166.4	474.1	6558.1	438.4	354.7	2332.8	10805.6	27569.5	1165.8	506.0	3071.7	4470.6	1563.5	5618.9	14019.2	199.3	540.3	7366.2	28630.5	72880.2	910.7	24148.3	642.3	11144.0	1143.5	5846.6	9902.5	3937.4	62630.3	527.3	24934.8	1212.8	32018.5	6127.1	2173.9	714.3	2804.0	3094.9	1982.0	1020.9	285.5	87348.2	2541.9	1176	1338.4	37511.4	644.9	8302.8	3755.0	382.5	951.5	2067.8	2886.5	273.7	2998.1	185.1	389.6	684.2	183.9	1127.4	1386.7	225088.3	1517	938.1	3460.8	16618.3	308.5	3474.0	48185.8	72494.5	181021.8	305.9	269.9	5088.5	375.2	461.3	801.4	994.4	171.2	2807.1	712.1	185.3	326.4	643.8	844.9	43968.8	427.4	1510.5	249.0	453.5	1802.9	18221.6	1259.4	188805.7	12107.6	553.1	301.4	171.1	921.5	1608.8	1802.4	11110.8	1828.2	4142.2	1491.2	2840.0	7616.2	707.5	1070.4	296.6	2836.3	254.7	22978.7	9370.2	933.2	371.1	2800.1	1838.8	7815.7	3285.7	2742.0	3331.8	7055.5	536.5	40683.4	262.3	371.5	2377.9	307.9	414.6	1418.0	4796.1	49466.2	2350.9	535.2	508.6	3160.1	1309.3	329542.6	1839.4	773.6	5456.3	956.3	6410.6	597.2	20624.3	2312.6	192.9	2541.2	1799.4	258273.0	257445.1	510.7	2507.0	24718.2	983.0	773.9	1080.2	711.2	783.8	5342.9	1096.1	847.8	108637.8	868.8	991.5	1869.9	9745.2	881.5	1343.5	4230.8	913.6	9335.7	322.4	2017.7	2455.6	1983.0	518.0	4777.6	677.1	8659.9	1073.7	805.5	690.6	9998.6	1008.1	326.7	661.4	8603.1	6301.7	1677.0	19673.9	504.4	3378.3	3797.7	14123.2	28690.8	423.5	116.7	1756.4	1568.2	4309.6	53610.1	2464.0	46849.4	767.7	502.7	3514.4	5320.0	2360.6	2655.1	742.8	3495.3	1232.2	38113.5	5671.8	1526.0	1506.2	4310.4	37104.0	489.7	461.2	36787.4	218.4	490.0	5023.2	1363.1	82103.8	1950.6	466.4	19539.3	593.0	3418.7	898.6	779.4	9255.1	92707.9	1991.6	312.7	2088.0	440.7	489.5	791.9	1141.1	13840.5	6225.3	1604.0	366.8	1041.3	10592.2	3717.6	501.3	1311.1	43942.4	28063.0	859.4	9425.7	400.0	2766.4	1970.8	626.4	11630.2	1071.2	1554.2	348	2697.4	258	242.3	793.1	2219.2	16515.6	1390.9	1199.4	2169.0	4049.8	4464.6	1423.9	181.8	3937.3	1045.0	368.5	536.6	229.5	7304.3	3048.2	7308.5	3007.8	2059.8	765	4099.4	1812.1	8078.3	2659.4	7201.2	470.9	412.2	41984.0	2427.3	3619.0	652.5	4998.0	1884.6	705.6	2831.9	3498.0	1196.4	4537.1	669.7	822.9	12259.1	435.7	2475.3	1370.1	1328.0	282.7	1114.3	950.2	159.0	3669.4	7624.8	51411.6	294.1	5651.3	2217.2	2077.2	10543.6	2351.4	844.0	457.6	2197.6	1099.3	38792.3	13916.1	310.8	137.7	3670.1	133119.1	745.5	12011.6	2976.7	2079.4	5228.5	4716.7	318.7	1020.0	1275.8	2122.9	382.9	180.9	4092	16296.9	1281.0	8574.0	24249.6	4601.4	240.1	649.6	538.9	1220.7	4043.1	86224.1	1088.6	788.4	98553.7	937.2	2767.2	8696.6	188.7	845.5	12164.1	863.8	484.6	351.6	2302.3	190.1	26436.1	1578.6	1139.2	321	3656.9	19102.7	2228.7	17038	6246.4	2019.3	762.7	592.8	758.1	4015.8	137.9	4646.5	84330.0	5011.1	6217.2	2201.8	23735.4	555.2	800.9	9534.6	767.9	8130.0	42594.8	2292.9	354.7	19149.5	6756.4	7873.4	1957.5	2795.3	2126.2	13577.0	1918.6	578.9	243.3	6530.5	3353.7	457.5	3902.2	7626.2	5564.2	1706.8	186.6	2298.1	16356.7	219.9	196.0	1179.0	148.0	164.0	2137.8	17545.3	99	1843.1	1323.4	4900.3	4706.2	5107.3	14298.1	1536.0	466.2	575.8	391.2	1392.2	38874.4	318.5	5537.6	1280.7	1810.8	1481.3	429.3	1471.6	657.8	5778.6	21619.4	422.5	2747.1	14980.5	829.7	5096.0	1511.4	7772.9	1729.0	19403.9	3327.2	2298.2	2780.7	1726.1	888.3	2831.8	5397.4	6920.5	1140.0	1206.0	1491.1	1635.2	3660.8	5810.2	1055.2	1646.5	893.2	9551.1	1672.2	3053.6	8949.0	3955.3	5576.8	511.7	858.7	7819.1	1450.5	28456.2	8281.9	895.5	2059.6	18869.5	10666.4	3809.9	20041.0	338.3	700.5	597.7	3016.1	197.0	788.4	1218.5	891.5	545.2	341.8	1753.9	13043.2	4242.7	1750.4	1146.8	1750.4	710.4	151.4	9594.0	1452.1	792.6	796.3	243.6	910.1	7175.9	25505.2	1576.0	8383.8	13404.6	636.0	2037.5	359.0	1844.4	20365.6	406.6	717.9	254.9	620.7	8071.7	14248.1	166090.2	3361.2	3238.0	121254.6	1314.1	27096.4	8689.0	2863.5	10680.5	604.4	1194.2	1001.0	284.2	27318.4	3490.7	5690.0	19178.2	1688.3	2217.9	858.2	530.7	656.5	1619.3	12143.3	31645.8	832.7	1464.8	487.3	396.1	1098.8	2038.5	5359.8	365.1	5579.5	19308.4	8654.9	371.8	261.9	6754.0	674.9	776.5	84197.8	345.3	24984.8	446.3	24298.9	860.1	205.4	354.5	4276.3	214.3	990.5	403.0	16251.4	240.8	1382.6	360.7	417.3	328.7	216.7	19932.8	68559.1	782.5	4282.3	22795.5	10035.3	30642.0	16977.3	252.6	1466.3	1953.8	63034.8	8384.7	251749.4	1505.3	405.8	7727.6	287.9	22711.9	7474.9	4893.4	179.4	12576.8	62304.7	913.3	6416	7847.3	2831.1	6694.3	7883.0	9226.8	1812.9	442.4	63355.5	277.6	492.8	34275.1	907.2	504.9	2703.6	202.1	214.9	402.2	27206.1	8114.9	231.6	668.9	9248.8	374.1	12484.8	23014.0	2287.7	557.1	230.2	60993.3	12186.5	11121.7	10160.3	168.4	18865.8	1252.3	30450.2	743.0	19977.1	3817.7	4761.0	2233.1	1397.1	805.6	211.6	3477.1	3199.4	380.2	148.1	4064.5	28269.8	5864.5	443.6	1985.4	384.3	269.1	7478.9	4802.2	1380.7	4012.7	366.5	424.5	1734.0	116.5	191.1	740.7	1742.1	3150.3	101.4	12477.5	588.1	4892.5	445.7	1948.7	1470.5	11732.3	13122.1	10417.7	127874.4	494.2	2182.4	1461.3	1306.6	294.0	18385.9	1651.6	15069.6	30073.8	4439.4	385.8	1910.1	10705.1	415.8	5970.1	1492.5	706.8	51945.8	755.6	668.1	1140.0	592.1	12069.6	624.5	715.6	681.2	312.1	739.8	112.8	10144.6	515.2	743.1	383.3	3913.1	3001.7	419.0	2795.2	660.5	606.7	295.4	440.9	8105.7	1803.5	4912.3	3478.7	3140.6	5871.8	10637.4	26374.9	161.1	4208.6	2471	1056.2	704.5	5160.0	799.9	912.6	551.2	45561.8	2127.3	736.4	5601.8	1440.5	2843.5	3713.5	1056.0	689.8	917.6	505.4	1010.8	672.7	2894.2	6250.9	2226.6	2682.8	147.3	682.6	275.1	458.4	4463.2	198.6	2617.5	371.6	3461.7	71107.2	17738.7	1421.1	522.9	719.3	5937.1	3002.9	22976.3	593.4	2823.8	1706.3	1060.1	105011.0	322.5	10727.9	820.1	562.6	5131.1	1938.9	1608.1	982.7	1510.3	780.0	9103.2	5531.6	3592.7	3490.2	87027.7	2984.2	5450.8	884.2	13235.8	237.6	5764.5	237.0	10719.1	4293.6	3760.6	341.4	8603.7	7362.9	3834.9	889.2	317.7	224.7	1189.0	79394.2	1758.1	736.3	23710.3	172	291.9	1469.8	4333.4	540.5	116972.1	749.2	10073.2	1082.8	822.6	1396.7	489.1	3466.1	54020	2120.1	512.2	29629.4	10168.6	1123.4	900.5	822.9	577.7	399.6	2191.8	5000.7	35316.5	1338.4	2368.4	961.0	3063.2	641.7	5980.0	189.0	453.4	974.6	1953.2	363.4	1531.7	1024.3	1861.0	900.6	180.7	400.7	4394.2	1322.5	16040.8	572.2	389.4	18570.1	1704.9	5058.3	924.5	1299.3	279.0	1588.2	5261.3	290.4	4101.6	8151.1	604.5	412.2	567.3	1171.0	300.0	429.6	349.8	5227.5	618.1	795.3	907.2	2263.5	1248.3	1048.8	21944.1	645.0	16456.0	852.0	1103.0	2419.3	1255.8	2369.4	3667.3	372.4	3890.4	10319.3	1300.3	20466.8	446.6	9121.5	284.4	757.0	1352.8	814.9	8321.8	181.8	3755.9	5745.9	414.8	428.8	1113.8	5083.5	462.0	27509.0	278.1	477.3	14272.9	573.1	2156.9	1165.8	2596.4	361	631.5	550.1	1835.4	44495.2	1043.4	12265.9	6825.2	31793.1	4384.5	3380.5	4122.4	914.9	1497.5	1260.7	26841.3	4391.2	2491.2	1837.6	1748.6	3453.1	634.7	930.7	14941.3	22715.1	33135.7	889.6	9870.6	4395.5	528.5	334398.4	3157.9	127148.1	202.7	14978.2	1053.9	3867.6	4097.2	1664.5	14611.1	3633.3	938.0	2209.0	1772.9	3386.7	713.2	3553.9	1069.0	730.6	1642.7	937.3	7045.0	982.0	22910.2	3695.1	761.1	2284.1	1982.7	4273.8	3759.6	7486.8	4083.2	7014.4	1238.4	9609.4	11961.7	5102.3	845.6	832.8	17793.9	1215.4	8224.1	2405.2	1313.5	6926.2	508.2	780.5	58638.3	2346.4	57372.2	999.3	71002.7	15157.0	500.8	523.4	57557.0	2085.5	322.5	25211.4	967.3	1431.4	3617.9	102012.3	12657.5	3206.2	903.6	1999.2	2754.9	1052.7	2043.2	752.7	797.9	381.3	3111.4	854.1	3034.1	567.8	8083.3	282.6	2150.6	980.8	372.3	470.6	236.9	4634.8	715.6	4747.5	722.7	181.6	188129.3	5750.6	97979.7	2291.6	15313.5	1343.0	688.8	11073.1	47034.9	556.0	1626.8	1889.4	1838.8	1907.8	1370.4	299.0	1453.5	9211.1	515.3	746.4	229.4	2312.5	1562.8	3295.4	1099.0	1826.3	5250.4	423.2	940.3	513.0	1500.0	3907.6	13183.5	39637.7	1589.9	18272.9	146051.5	329.3	804.6	210.0	15740.1	18865.7	327.2	437.5	392.8	1136.4	805.9	3555.8	1109.2	234.3	759.2	7830.5	689.9	2022.8	3570.5	1338.4	1766.3	854.1	4236.0	368.9	4778.9	1234.7	656.5	1042.1	1209.8	1272.9	157.8	428.0	2019.8	1649.4	2724.6	648.8	532.4	401.7	7170.7	789.2	1254.3	6504.0	8694.6	7546.4	747.6	2157.8	55489.3	3647.6	3005.5	3903.4	4412.9
PDAL120HLU	0	65	65	13	Female	21	305	PD	UTSW	64.5	305	72	Female	Set.4	1942.8	774.1	47926.6	649.6	1108.5	2704.5	1255.0	7462.3	824.6	275.0	308.4	19176.7	21014.7	1655.5	2308.3	193.9	17054.5	561.6	1724.2	3085.3	616.9	1921.2	4169.4	480.3	3550.2	472.8	220.6	2104.0	10045.5	10098.0	68400.3	33851.5	505.7	1819.7	7667.6	1081.2	411.7	388.9	1901.4	1744.9	1540.5	656.2	557.7	613.7	19890.3	40190.5	4222.5	1859.1	1094.6	1187.8	5590.0	1847.7	36773.2	12704.1	2107.4	344.2	2018.0	3174.5	8902.6	25239.3	5798.1	6428.8	68375.3	3244.0	199.1	602.7	1011.3	6141.4	1339.9	10232.8	1942.7	1710.7	1066.1	795.8	340.1	488.3	962	15662.2	477.1	343.8	193.3	18952.9	1087.7	13333.1	2358.8	857.9	13971.7	608.7	11216.0	475.1	2156.5	848.8	343.5	558.2	2332	1741.3	25036.4	1001.3	1048.0	3788.8	279.1	1276.6	1067.7	61419.5	82.8	262.1	168.0	485.4	1222.1	4965.8	8723.6	27719.5	923.8	2567.4	615.2	15423.1	177.3	763.5	247.4	264.3	102.4	23189.2	18485.0	1520.3	428.3	54125.8	719.1	713.3	5828.4	23335.8	5641.1	12524.5	723.0	38419.6	2767.3	673.9	7343.9	15394.9	516.0	12040.6	349.9	285.6	188.6	479.1	916.8	352.0	2940.1	739.5	1398.1	1931.3	4187.4	326.3	311.7	132.4	301.1	7684.9	359.4	361.5	1615.5	9773.9	30930.9	1066.4	402.9	2480.5	3549.2	1785.6	5339.1	10676.0	239.4	399.0	5816.0	21563.9	87365.3	868.6	18163.0	688.0	12336.5	1342.5	7840.2	6913.3	4274.1	50640.6	394.2	23083.1	18830.0	28508.4	5879.6	2226.9	788.9	2831.2	2097.1	1770.8	747.4	151.8	38354.3	4206.5	745	1740.0	52671.3	711.0	8930.3	2234.8	305.8	637.6	1842.4	2734.0	383.2	4765.0	121.9	287.1	520.2	209.7	1049.3	1408.9	162635.9	1299	793.4	6062.3	15589.3	220.1	1552.4	36705.7	40847.8	127472.6	236.3	238.8	19381.4	293.7	383.2	781.0	858.1	118.2	2220.4	477.2	151.2	264.5	592.2	795.0	32874.4	1205.7	1461.9	180.3	420.8	1345.3	8270.0	991.5	165395.2	6369.2	438.2	214.3	136.7	732.2	2189.7	1855.5	15254.0	1532.2	3802.0	1844.0	3057.7	8110.7	524.0	1492.2	228.0	3608.6	356.9	15184.6	9200.8	677.7	211.4	2499.2	1599.0	7282.6	2356.6	4422.8	2421.0	6547.2	460.1	44954.8	137.9	219.3	2187.1	238.3	361.2	1226.2	6349.1	36154.1	2126.6	418.0	368.7	2306.9	1187.0	255289.9	1711.8	604.1	7166.3	674.9	5828.4	402.4	22975.0	2466.4	137.8	407.9	794.1	207096.3	208185.7	434.6	2774.5	17749.4	1340.5	523.8	1090.3	1191.6	603.1	5335.9	1349.2	3068.3	112106.9	1092.4	803.0	1064.2	11642.9	1181.5	1069.1	3471.0	492.9	9621.9	304.6	1660.7	2529.8	993.9	400.1	4105.9	529.6	2221.1	801.7	1043.0	556.9	12113.6	1081.4	211.5	829.1	10427.1	5821.9	1539.3	32285.7	482.5	3593.3	3277.0	237.8	35558.9	566.5	113.2	1999.6	2121.1	5043.3	62823.4	1941.9	37159.8	8872.9	364.5	408.7	4279.3	1481.6	2540.5	657.5	4641.6	1429.1	18304.7	7532.3	1254.9	914.4	7793.1	8422.4	459.2	305.1	29689.1	184.1	356.1	2981.7	3521.9	78801.0	1764.2	329.3	22245.4	302.2	1820.4	2015.5	479.6	10168.2	80718.6	3960.4	246.8	2491.5	332.0	234.8	698.2	690.1	10737.5	4013.9	1359.6	302.6	800.8	11888.7	4280.8	385.2	1159.4	38729.5	23827.1	26428.3	5809.7	296.9	3060.3	2025.0	490.8	6366.3	661.5	1325.8	516	3021.6	181	150.7	720.8	1109.3	11343.9	2104.3	1595.0	1902.1	4613.9	5417.8	943.1	127.7	3156.7	738.8	536.6	435.1	197.5	3097.3	6094.9	4244.7	2369.2	1071.5	1164	4973.7	1305.2	6731.6	3230.9	7282.0	513.7	302.1	29156.7	3621.3	3522.2	571.1	6257.9	2546.2	516.4	1465.7	2773.9	1208.6	3882.2	493.8	578.9	6219.8	473.2	3119.9	1387.9	2294.7	227.0	1193.5	1282.8	111.3	2621.6	5615.2	53137.1	198.1	7129.3	2051.4	3039.8	11053.6	3303.9	699.8	392.4	2065.8	635.2	48153.8	18423.4	677.1	105.5	3277.8	130745.3	578.8	12949.6	2080.3	1814.0	4289.4	7156.4	285.7	277.2	1032.5	1571.6	132.4	149.8	2909	13145.7	1132.6	6607.6	20635.8	6579.9	182.3	215.0	401.6	1016.1	3252.1	86840.9	851.7	511.6	89385.2	869.3	2099.4	7477.2	159.6	929.1	9721.2	682.9	314.0	259.1	4300.4	163.9	29396.1	1180.6	801.0	259	6342.2	16008.9	1638.7	15499	6366.2	2450.9	577.1	447.7	2010.9	11059.0	115.9	1786.7	48932.7	3347.6	8330.0	2477.0	20234.5	358.6	750.5	11113.4	691.7	7997.4	35585.0	2343.4	278.2	17652.7	6168.0	13091.0	1638.7	3894.5	1569.2	15443.3	1562.8	418.2	169.5	3880.2	2220.2	398.4	3940.8	11187.0	4519.7	2128.6	154.3	1964.1	5981.0	163.4	185.3	1361.4	113.8	122.3	1905.3	26281.7	134	2045.0	910.0	5344.6	4325.0	5343.3	11289.1	2572.2	636.0	763.4	295.6	315.4	32060.9	236.2	6905.5	891.1	2446.2	963.4	311.4	1319.6	417.1	5807.8	29717.2	344.4	1645.4	13999.2	508.3	4684.3	1351.8	5322.3	1104.4	15303.7	2311.4	3283.1	2381.2	3579.8	567.6	2049.0	4867.3	6057.6	1015.3	2454.2	1101.8	1561.5	2287.9	2259.2	815.2	1288.5	669.5	12635.9	1216.8	2162.4	8085.9	4799.7	4749.0	328.9	589.9	5453.7	933.5	29756.4	6417.1	729.4	1707.3	8755.4	11550.2	3225.8	16317.1	321.8	790.7	440.4	3507.5	173.3	666.5	1143.8	598.3	379.6	227.3	1844.2	1462.4	3485.3	1244.8	4583.3	1922.2	515.7	78.7	4891.7	1403.2	629.6	351.1	452.1	677.2	868.9	19203.0	592.2	4338.1	9481.9	414.2	1195.4	283.4	1697.6	15073.1	275.2	608.8	162.4	485.9	10239.8	7990.9	135346.2	4398.2	3084.9	100918.6	942.3	18633.5	6855.4	2039.5	16440.2	477.2	871.8	952.4	193.3	26260.4	1216.7	5750.2	16320.7	1467.4	1678.7	623.0	332.8	426.0	290.1	16750.6	23477.0	651.5	1289.4	314.5	275.6	919.7	4287.7	4167.6	404.9	4361.2	18181.8	5958.9	331.2	184.8	8142.5	520.0	297.6	72402.1	258.2	23402.8	346.3	6729.7	669.2	162.5	252.1	9445.3	210.4	254.2	313.5	16335.2	113.2	1486.6	280.5	316.0	205.8	155.3	15603.4	42072.1	529.6	3534.2	19922.2	6040.5	18702.7	18215.2	177.7	738.4	1774.7	63903.6	9298.7	247597.6	1006.7	286.9	6179.9	189.7	13938.4	5117.3	4797.1	169.2	11530.1	49088.3	862.1	2912	5597.9	2979.2	8923.4	5588.9	4682.7	1599.6	378.4	52398.7	197.2	502.5	33424.6	1090.1	598.4	2053.5	152.5	175.9	380.2	25362.4	6381.6	186.6	564.6	6048.0	304.1	8258.8	17177.5	3554.9	393.7	188.5	43906.5	8731.2	15610.5	6479.0	220.9	27152.4	1869.8	17334.6	2671.3	12421.5	3294.0	3212.6	1821.4	1468.7	584.0	204.6	2647.0	401.8	281.9	139.9	2707.9	30568.3	4715.9	341.4	1439.0	269.9	243.1	4704.0	6163.9	993.4	3618.2	332.9	327.6	1414.3	95.7	152.3	1057.2	2587.8	2397.5	109.8	15232.2	466.0	4533.4	186.7	1815.5	1138.4	11048.7	7311.0	5849.2	105731.0	581.6	2065.8	1191.4	1440.6	248.5	21378.8	1552.0	13905.4	15380.7	2554.1	307.1	1710.2	15144.0	322.5	7226.2	1124.7	388.3	27141.3	499.6	757.9	888.3	636.3	4969.8	488.7	579.0	597.4	326.3	645.9	94.0	5753.0	474.3	766.9	316.5	4076.1	2441.6	274.5	11775.7	373.9	423.8	303.6	365.0	5250.0	1350.2	3581.7	1160.8	2625.3	4125.0	13458.1	40857.5	149.0	2245.7	2933	1020.1	496.2	4436.7	649.7	1150.6	784.1	33585.6	2245.7	653.4	5250.2	1002.3	4000.5	1257.1	724.5	532.3	752.1	386.0	1182.8	472.6	4238.7	10250.8	5210.1	3309.6	141.1	950.5	173.4	357.1	6561.4	192.1	1863.0	307.2	3018.4	68072.0	12790.0	1861.7	439.3	998.9	6156.6	2799.2	16736.3	2898.3	348.6	3865.2	960.4	100120.3	296.1	9447.3	586.1	582.0	6099.0	2359.7	1730.3	825.7	1300.3	666.9	7006.7	13503.9	3420.6	2451.9	106187.1	1626.2	4381.5	1406.8	6377.8	161.0	4290.9	161.9	14539.5	3288.2	5355.1	249.9	5935.6	6172.0	2726.9	625.3	268.9	299.3	608.9	60807.8	1238.5	620.7	21727.7	164	182.0	1285.6	5587.8	415.8	114517.4	960.7	7390.0	735.4	676.7	1008.1	459.6	2933.5	37558	2283.0	470.8	17469.2	7215.7	1215.4	677.6	534.9	413.8	353.5	1516.4	4442.5	36039.1	1982.6	1102.6	545.4	4423.0	953.5	6408.6	122.3	404.9	778.6	2348.1	303.9	1482.1	903.2	1586.6	743.1	141.8	241.3	5091.1	583.7	17557.2	555.4	254.5	21874.5	1598.1	6092.3	750.3	888.0	241.2	2666.5	2512.8	300.2	4249.6	11202.1	628.1	213.6	374.8	1123.4	229.7	299.0	287.4	6367.8	304.5	541.2	906.3	3453.0	1321.2	672.0	22681.1	704.9	15649.3	680.8	1029.9	2445.2	909.6	2655.8	3101.9	302.0	5629.3	12834.8	1163.8	23614.8	354.0	9450.3	243.8	878.3	1093.1	681.5	10749.4	136.5	3853.2	5763.3	329.8	260.3	912.6	3946.9	368.9	33093.8	183.5	392.4	9911.0	573.5	1575.8	920.2	2295.7	265	607.3	397.1	1693.7	70699.1	1198.9	10261.5	5288.0	28416.1	3735.3	2258.4	2746.0	625.4	1388.1	1085.3	28428.1	3454.4	2270.8	1482.6	1343.4	1809.7	364.9	2309.8	11646.3	23347.6	28257.9	636.2	14039.7	7082.2	269.6	265712.9	3123.1	146883.0	193.0	10186.9	996.2	3313.2	3483.3	1825.5	12022.8	4813.5	309.6	1855.4	1590.2	3100.1	459.6	5274.7	740.1	399.8	1175.8	668.1	15392.6	594.6	22265.5	2911.1	635.8	2117.8	1548.1	1752.3	2052.3	8751.6	3772.8	7456.2	1193.7	12674.3	35717.4	4348.2	468.6	1015.0	16774.8	1287.8	5812.9	3009.4	1341.4	5766.1	191.2	748.5	70387.6	2060.2	47959.1	811.3	61389.5	10750.5	401.3	439.1	42496.4	1169.8	222.3	15033.8	542.8	1164.9	37919.1	93439.6	8319.1	3325.1	563.1	1201.7	2699.9	610.6	1122.5	646.1	797.3	278.1	3152.9	596.4	1848.9	428.6	6102.4	184.1	411.7	903.5	339.6	522.0	185.9	3904.9	613.9	2793.1	1100.2	129.5	164162.3	4589.3	81351.5	935.8	10950.4	1161.4	617.2	19176.2	46386.3	255.6	1518.7	1566.9	677.7	253.0	1246.2	179.8	869.1	13060.6	385.8	789.3	240.2	2530.8	1231.7	2202.1	735.5	1160.9	5096.5	477.3	757.3	491.3	1151.9	3473.0	8744.1	27201.5	1961.1	11932.4	97435.5	192.9	1267.7	204.8	9657.3	16653.9	266.6	849.9	296.3	1077.4	800.6	406.0	1012.6	108.8	684.1	12383.9	548.9	2135.1	11116.1	380.8	984.9	948.3	3463.9	271.5	4425.8	1327.6	426.1	979.2	970.8	1594.3	162.6	392.7	3068.9	2262.0	3092.3	833.7	453.4	365.9	11557.3	614.8	1261.6	4799.3	5252.0	5389.9	629.5	1338.5	56533.7	1992.0	5103.9	12593.1	4576.5
PDAL120HLU	1	65	66	14	Female	25	305	PD	UTSW	64.5	305	72	Female	Set.4	1942.8	774.1	47926.6	649.6	1108.5	2704.5	1255.0	7462.3	824.6	275.0	308.4	19176.7	21014.7	1655.5	2308.3	193.9	17054.5	561.6	1724.2	3085.3	616.9	1921.2	4169.4	480.3	3550.2	472.8	220.6	2104.0	10045.5	10098.0	68400.3	33851.5	505.7	1819.7	7667.6	1081.2	411.7	388.9	1901.4	1744.9	1540.5	656.2	557.7	613.7	19890.3	40190.5	4222.5	1859.1	1094.6	1187.8	5590.0	1847.7	36773.2	12704.1	2107.4	344.2	2018.0	3174.5	8902.6	25239.3	5798.1	6428.8	68375.3	3244.0	199.1	602.7	1011.3	6141.4	1339.9	10232.8	1942.7	1710.7	1066.1	795.8	340.1	488.3	962	15662.2	477.1	343.8	193.3	18952.9	1087.7	13333.1	2358.8	857.9	13971.7	608.7	11216.0	475.1	2156.5	848.8	343.5	558.2	2332	1741.3	25036.4	1001.3	1048.0	3788.8	279.1	1276.6	1067.7	61419.5	82.8	262.1	168.0	485.4	1222.1	4965.8	8723.6	27719.5	923.8	2567.4	615.2	15423.1	177.3	763.5	247.4	264.3	102.4	23189.2	18485.0	1520.3	428.3	54125.8	719.1	713.3	5828.4	23335.8	5641.1	12524.5	723.0	38419.6	2767.3	673.9	7343.9	15394.9	516.0	12040.6	349.9	285.6	188.6	479.1	916.8	352.0	2940.1	739.5	1398.1	1931.3	4187.4	326.3	311.7	132.4	301.1	7684.9	359.4	361.5	1615.5	9773.9	30930.9	1066.4	402.9	2480.5	3549.2	1785.6	5339.1	10676.0	239.4	399.0	5816.0	21563.9	87365.3	868.6	18163.0	688.0	12336.5	1342.5	7840.2	6913.3	4274.1	50640.6	394.2	23083.1	18830.0	28508.4	5879.6	2226.9	788.9	2831.2	2097.1	1770.8	747.4	151.8	38354.3	4206.5	745	1740.0	52671.3	711.0	8930.3	2234.8	305.8	637.6	1842.4	2734.0	383.2	4765.0	121.9	287.1	520.2	209.7	1049.3	1408.9	162635.9	1299	793.4	6062.3	15589.3	220.1	1552.4	36705.7	40847.8	127472.6	236.3	238.8	19381.4	293.7	383.2	781.0	858.1	118.2	2220.4	477.2	151.2	264.5	592.2	795.0	32874.4	1205.7	1461.9	180.3	420.8	1345.3	8270.0	991.5	165395.2	6369.2	438.2	214.3	136.7	732.2	2189.7	1855.5	15254.0	1532.2	3802.0	1844.0	3057.7	8110.7	524.0	1492.2	228.0	3608.6	356.9	15184.6	9200.8	677.7	211.4	2499.2	1599.0	7282.6	2356.6	4422.8	2421.0	6547.2	460.1	44954.8	137.9	219.3	2187.1	238.3	361.2	1226.2	6349.1	36154.1	2126.6	418.0	368.7	2306.9	1187.0	255289.9	1711.8	604.1	7166.3	674.9	5828.4	402.4	22975.0	2466.4	137.8	407.9	794.1	207096.3	208185.7	434.6	2774.5	17749.4	1340.5	523.8	1090.3	1191.6	603.1	5335.9	1349.2	3068.3	112106.9	1092.4	803.0	1064.2	11642.9	1181.5	1069.1	3471.0	492.9	9621.9	304.6	1660.7	2529.8	993.9	400.1	4105.9	529.6	2221.1	801.7	1043.0	556.9	12113.6	1081.4	211.5	829.1	10427.1	5821.9	1539.3	32285.7	482.5	3593.3	3277.0	237.8	35558.9	566.5	113.2	1999.6	2121.1	5043.3	62823.4	1941.9	37159.8	8872.9	364.5	408.7	4279.3	1481.6	2540.5	657.5	4641.6	1429.1	18304.7	7532.3	1254.9	914.4	7793.1	8422.4	459.2	305.1	29689.1	184.1	356.1	2981.7	3521.9	78801.0	1764.2	329.3	22245.4	302.2	1820.4	2015.5	479.6	10168.2	80718.6	3960.4	246.8	2491.5	332.0	234.8	698.2	690.1	10737.5	4013.9	1359.6	302.6	800.8	11888.7	4280.8	385.2	1159.4	38729.5	23827.1	26428.3	5809.7	296.9	3060.3	2025.0	490.8	6366.3	661.5	1325.8	516	3021.6	181	150.7	720.8	1109.3	11343.9	2104.3	1595.0	1902.1	4613.9	5417.8	943.1	127.7	3156.7	738.8	536.6	435.1	197.5	3097.3	6094.9	4244.7	2369.2	1071.5	1164	4973.7	1305.2	6731.6	3230.9	7282.0	513.7	302.1	29156.7	3621.3	3522.2	571.1	6257.9	2546.2	516.4	1465.7	2773.9	1208.6	3882.2	493.8	578.9	6219.8	473.2	3119.9	1387.9	2294.7	227.0	1193.5	1282.8	111.3	2621.6	5615.2	53137.1	198.1	7129.3	2051.4	3039.8	11053.6	3303.9	699.8	392.4	2065.8	635.2	48153.8	18423.4	677.1	105.5	3277.8	130745.3	578.8	12949.6	2080.3	1814.0	4289.4	7156.4	285.7	277.2	1032.5	1571.6	132.4	149.8	2909	13145.7	1132.6	6607.6	20635.8	6579.9	182.3	215.0	401.6	1016.1	3252.1	86840.9	851.7	511.6	89385.2	869.3	2099.4	7477.2	159.6	929.1	9721.2	682.9	314.0	259.1	4300.4	163.9	29396.1	1180.6	801.0	259	6342.2	16008.9	1638.7	15499	6366.2	2450.9	577.1	447.7	2010.9	11059.0	115.9	1786.7	48932.7	3347.6	8330.0	2477.0	20234.5	358.6	750.5	11113.4	691.7	7997.4	35585.0	2343.4	278.2	17652.7	6168.0	13091.0	1638.7	3894.5	1569.2	15443.3	1562.8	418.2	169.5	3880.2	2220.2	398.4	3940.8	11187.0	4519.7	2128.6	154.3	1964.1	5981.0	163.4	185.3	1361.4	113.8	122.3	1905.3	26281.7	134	2045.0	910.0	5344.6	4325.0	5343.3	11289.1	2572.2	636.0	763.4	295.6	315.4	32060.9	236.2	6905.5	891.1	2446.2	963.4	311.4	1319.6	417.1	5807.8	29717.2	344.4	1645.4	13999.2	508.3	4684.3	1351.8	5322.3	1104.4	15303.7	2311.4	3283.1	2381.2	3579.8	567.6	2049.0	4867.3	6057.6	1015.3	2454.2	1101.8	1561.5	2287.9	2259.2	815.2	1288.5	669.5	12635.9	1216.8	2162.4	8085.9	4799.7	4749.0	328.9	589.9	5453.7	933.5	29756.4	6417.1	729.4	1707.3	8755.4	11550.2	3225.8	16317.1	321.8	790.7	440.4	3507.5	173.3	666.5	1143.8	598.3	379.6	227.3	1844.2	1462.4	3485.3	1244.8	4583.3	1922.2	515.7	78.7	4891.7	1403.2	629.6	351.1	452.1	677.2	868.9	19203.0	592.2	4338.1	9481.9	414.2	1195.4	283.4	1697.6	15073.1	275.2	608.8	162.4	485.9	10239.8	7990.9	135346.2	4398.2	3084.9	100918.6	942.3	18633.5	6855.4	2039.5	16440.2	477.2	871.8	952.4	193.3	26260.4	1216.7	5750.2	16320.7	1467.4	1678.7	623.0	332.8	426.0	290.1	16750.6	23477.0	651.5	1289.4	314.5	275.6	919.7	4287.7	4167.6	404.9	4361.2	18181.8	5958.9	331.2	184.8	8142.5	520.0	297.6	72402.1	258.2	23402.8	346.3	6729.7	669.2	162.5	252.1	9445.3	210.4	254.2	313.5	16335.2	113.2	1486.6	280.5	316.0	205.8	155.3	15603.4	42072.1	529.6	3534.2	19922.2	6040.5	18702.7	18215.2	177.7	738.4	1774.7	63903.6	9298.7	247597.6	1006.7	286.9	6179.9	189.7	13938.4	5117.3	4797.1	169.2	11530.1	49088.3	862.1	2912	5597.9	2979.2	8923.4	5588.9	4682.7	1599.6	378.4	52398.7	197.2	502.5	33424.6	1090.1	598.4	2053.5	152.5	175.9	380.2	25362.4	6381.6	186.6	564.6	6048.0	304.1	8258.8	17177.5	3554.9	393.7	188.5	43906.5	8731.2	15610.5	6479.0	220.9	27152.4	1869.8	17334.6	2671.3	12421.5	3294.0	3212.6	1821.4	1468.7	584.0	204.6	2647.0	401.8	281.9	139.9	2707.9	30568.3	4715.9	341.4	1439.0	269.9	243.1	4704.0	6163.9	993.4	3618.2	332.9	327.6	1414.3	95.7	152.3	1057.2	2587.8	2397.5	109.8	15232.2	466.0	4533.4	186.7	1815.5	1138.4	11048.7	7311.0	5849.2	105731.0	581.6	2065.8	1191.4	1440.6	248.5	21378.8	1552.0	13905.4	15380.7	2554.1	307.1	1710.2	15144.0	322.5	7226.2	1124.7	388.3	27141.3	499.6	757.9	888.3	636.3	4969.8	488.7	579.0	597.4	326.3	645.9	94.0	5753.0	474.3	766.9	316.5	4076.1	2441.6	274.5	11775.7	373.9	423.8	303.6	365.0	5250.0	1350.2	3581.7	1160.8	2625.3	4125.0	13458.1	40857.5	149.0	2245.7	2933	1020.1	496.2	4436.7	649.7	1150.6	784.1	33585.6	2245.7	653.4	5250.2	1002.3	4000.5	1257.1	724.5	532.3	752.1	386.0	1182.8	472.6	4238.7	10250.8	5210.1	3309.6	141.1	950.5	173.4	357.1	6561.4	192.1	1863.0	307.2	3018.4	68072.0	12790.0	1861.7	439.3	998.9	6156.6	2799.2	16736.3	2898.3	348.6	3865.2	960.4	100120.3	296.1	9447.3	586.1	582.0	6099.0	2359.7	1730.3	825.7	1300.3	666.9	7006.7	13503.9	3420.6	2451.9	106187.1	1626.2	4381.5	1406.8	6377.8	161.0	4290.9	161.9	14539.5	3288.2	5355.1	249.9	5935.6	6172.0	2726.9	625.3	268.9	299.3	608.9	60807.8	1238.5	620.7	21727.7	164	182.0	1285.6	5587.8	415.8	114517.4	960.7	7390.0	735.4	676.7	1008.1	459.6	2933.5	37558	2283.0	470.8	17469.2	7215.7	1215.4	677.6	534.9	413.8	353.5	1516.4	4442.5	36039.1	1982.6	1102.6	545.4	4423.0	953.5	6408.6	122.3	404.9	778.6	2348.1	303.9	1482.1	903.2	1586.6	743.1	141.8	241.3	5091.1	583.7	17557.2	555.4	254.5	21874.5	1598.1	6092.3	750.3	888.0	241.2	2666.5	2512.8	300.2	4249.6	11202.1	628.1	213.6	374.8	1123.4	229.7	299.0	287.4	6367.8	304.5	541.2	906.3	3453.0	1321.2	672.0	22681.1	704.9	15649.3	680.8	1029.9	2445.2	909.6	2655.8	3101.9	302.0	5629.3	12834.8	1163.8	23614.8	354.0	9450.3	243.8	878.3	1093.1	681.5	10749.4	136.5	3853.2	5763.3	329.8	260.3	912.6	3946.9	368.9	33093.8	183.5	392.4	9911.0	573.5	1575.8	920.2	2295.7	265	607.3	397.1	1693.7	70699.1	1198.9	10261.5	5288.0	28416.1	3735.3	2258.4	2746.0	625.4	1388.1	1085.3	28428.1	3454.4	2270.8	1482.6	1343.4	1809.7	364.9	2309.8	11646.3	23347.6	28257.9	636.2	14039.7	7082.2	269.6	265712.9	3123.1	146883.0	193.0	10186.9	996.2	3313.2	3483.3	1825.5	12022.8	4813.5	309.6	1855.4	1590.2	3100.1	459.6	5274.7	740.1	399.8	1175.8	668.1	15392.6	594.6	22265.5	2911.1	635.8	2117.8	1548.1	1752.3	2052.3	8751.6	3772.8	7456.2	1193.7	12674.3	35717.4	4348.2	468.6	1015.0	16774.8	1287.8	5812.9	3009.4	1341.4	5766.1	191.2	748.5	70387.6	2060.2	47959.1	811.3	61389.5	10750.5	401.3	439.1	42496.4	1169.8	222.3	15033.8	542.8	1164.9	37919.1	93439.6	8319.1	3325.1	563.1	1201.7	2699.9	610.6	1122.5	646.1	797.3	278.1	3152.9	596.4	1848.9	428.6	6102.4	184.1	411.7	903.5	339.6	522.0	185.9	3904.9	613.9	2793.1	1100.2	129.5	164162.3	4589.3	81351.5	935.8	10950.4	1161.4	617.2	19176.2	46386.3	255.6	1518.7	1566.9	677.7	253.0	1246.2	179.8	869.1	13060.6	385.8	789.3	240.2	2530.8	1231.7	2202.1	735.5	1160.9	5096.5	477.3	757.3	491.3	1151.9	3473.0	8744.1	27201.5	1961.1	11932.4	97435.5	192.9	1267.7	204.8	9657.3	16653.9	266.6	849.9	296.3	1077.4	800.6	406.0	1012.6	108.8	684.1	12383.9	548.9	2135.1	11116.1	380.8	984.9	948.3	3463.9	271.5	4425.8	1327.6	426.1	979.2	970.8	1594.3	162.6	392.7	3068.9	2262.0	3092.3	833.7	453.4	365.9	11557.3	614.8	1261.6	4799.3	5252.0	5389.9	629.5	1338.5	56533.7	1992.0	5103.9	12593.1	4576.5

UTSW.UPDRS.merge$NCAM.120.Tertile <- with(Longitudinal, factor(
                            findInterval( NCAM.120, c(-Inf,
                               quantile(NCAM.120, probs=c(0.33,0.66)), Inf)), 
                            labels=c("First Tertile","Second Tertile","Third Tertile")))

# Train LME model to see how fasat and slow progressors differ
UPDRS = lmer(UPDRS3 ~ NCAM.120.Tertile*YearstoVisit + AgeAtTest + Sex + as.numeric(DiseaseDuration)+ (1 | GUID), data=UTSW.UPDRS.merge, REML=F)

data(efc)
theme_set(theme_sjplot())

p5 = plot_model(UPDRS, type = "pred", terms = c("YearstoVisit", "NCAM.120.Tertile"),
           title = " Cognitive Change \n (UTSW + Penn State Cohort)",
           axis.title = c("YearstoVisit","Cognition(MoCA)"),
           axis.labels = NULL, legend.title = "NCAM.120 Tertile",
           wrap.title = 50, wrap.labels = 25, axis.lim = NULL, grid.breaks = NULL,
           ci.lvl = 0.9, se = NULL, colors = "Set2", order.terms = c(3,1,2)) + scale_y_continuous(limits = c(0, 30), breaks = c(0,10,20,30,40)) + theme_classic() +
  theme(legend.position = c(0.25, 0.2), legend.title = element_text(face = "bold", size = 16), legend.text = element_text(size = 20),
        title = element_text(size = 23),
        axis.title.x = element_text(size = 25, margin = margin(t = 10, r = 0, b = 0, l = 0)),
        axis.title.y = element_text(size = 25, margin = margin(t = 0, r = 12, b = 0, l = 0)),
        axis.text = element_text(size = 25, color = "black"), axis.line = element_line(size = 1), axis.ticks = element_line(size = 1))

p5

BMIN503 Final Project

Junchao Shen

12/10/2021